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Struggling to lose weight?

You’re not alone. We offer a range of brand-name prescription weight loss medications, including Ozempic, Wegovy, and Mounjaro, as well as compounded tirzepatide and compounded semaglutide.

What kind of weight loss can you expect with GLP-1 weight loss medications?


-5 lbs

Month 2

Ramp up


Month 4



Month 6
-5 lbs -19 lbs -30 lbs
Dose = 0.25-0.5 mg Dose = 1 mg Dose = 1.25 mg
Month 2 Month 4 Month 6

GLP-1 injections help with weight loss by reducing appetite and increasing satiety (feeling full), leading to lower calorie intake. Additionally, GPL-1 medications slow digestion, allowing you to feel fuller for longer.  Individual weight loss progress depends on many different things: sticking to the treatment, diet, exercise, and overall health. 

While most people start seeing results after 2-3 months, the real weight loss is most commonly seen after six months of treatment.

Here’s an example of a common weight loss result, six months after beginning a GPL-1 medication. 

(This is a hypothetical guide, based on a person who began treatment at 200 lbs) 

Average weight loss:

Studies have shown that GLP-1 drugs can lead to an average weight loss of 10.5 to 15.8 pounds (4.8 to 7.2 kg). Source

Higher potential:

Some medications, like tirzepatide, have shown potential for even greater weight loss, with studies showing an average of 20% body weight loss at the highest dose. Source

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Beyond Willpower: GLP-1's Powerful Role in Curbing Hunger

The data is in. Long-term, sustainable weight loss isn’t about willpower. It’s about biology. Research shows that GLP-1s with healthy lifestyle tweaks are the safest and most effective long-term option for weight loss. 

Exciting developments in new prescription weight loss medications offer more effective options for managing obesity and overweight conditions. These GLP-1 receptor agonists mimic natural hormones to regulate appetite, leading to significant and sustainable long-term weight loss.

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Get Semaglutide Prescription Online

Our telehealth consultations allow you to connect with a healthcare provider remotely. They can assess your eligibility for prescription weight loss medication and guide you on the right medication.

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If you qualify, the appropriate medication will be prescribed.

Why choose IsraelPharm to get your weight loss medications online?

Brand-name medications

IsraelPharm has been delivering low-cost prescription medications for over 15 years worldwide. Purchases are secure and trackable.

Secure online purchase

Our secure online platform lets you purchase brand-name medications at competitive prices from the comfort of your home.

Affordable pricing

Unlike the United States, where prescription drug prices can be staggering, Israel sets a maximum price cap. Enjoy lower prices regardless of your location.

Telehealth solutions

Connect with licensed healthcare professionals who will assess your needs and prescribe appropriate medication.

Buy brand-name GLP-1 weight loss medications for less.

We understand the importance of cost-effective weight loss medications.
That’s why we offer a convenient and affordable way to buy brand-name GLP-1 weight loss medications for less.

Initially developed for treating type 2 diabetes, semaglutide has become popular for its ability to promote weight loss. Several medications are based on semaglutide, such as Ozempic, Rybelsus, and Wegovy. How can you determine which weight loss medication is most suitable for you? What sets semaglutide apart from tirzepatide? Is compounded tirzepatide or compounded semaglutide the better option for you? Or should you opt for the branded versions? Our telehealth service can assist you in comparing weight loss medications and help you find the most suitable choice for your needs.

Our telehealth service will help you explore the key differences in weight loss medications and help you understand what’s right for you.

Weight Loss FAQs

What are the new self-administered weekly injectable weight loss medications called?

Wegovy comes from Novo Nordisk, the company that introduced Ozempic. Both are based on a drug called semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist. Zepbound comes from Eli Lilly and Company, the company that introduced Mounjaro. Both are based on tirzepatide, which combines GLP-1 with a glucose-dependent insulinotropic polypeptide (GIP).

How does semaglutide work?

Wegovy injections include semaglutide, a compound that functions as a unique messenger within the body. Semaglutide assists in weight management through two different mechanisms.

  1. Imagine that your stomach is a balloon. Semaglutide allows the balloon to blow up slower, which makes you feel full for longer, so you don’t want to eat as much.
  2. There is a part of our brains that controls how hungry we feel. Semaglutide sends a signal to that part of the brain that says, “We’re good on food for now!” This signal helps people reduce their “inner chatter” about food and eat less.

Semaglutide is a medication, and it’s important to take it with healthy eating and exercise for the best results. It’s not a magic bullet, but it can be a very helpful tool.

Normally, our gut releases GLP-1 hormones that tell our brains that we’re full and slow down digestion. Semaglutide is like a super-powered version of GLP-1.

Here’s how it works: GLP-1 is a hormone produced when you eat. It plays several important roles in glucose metabolism and slows down food movement from your stomach. This keeps you feeling full for longer, naturally reducing your hunger pangs. Semaglutide mimics the effects of GLP-1. It works like hitting the pause button on your stomach so you don’t feel the urge to eat constantly. This can help people feel satisfied with less food, making weight management easier.

How does tirzepatide work?

Zepbound’s weekly injections have tirzepatide, which works like a double agent in the body’s ability to manage weight loss. It works differently than some other weight loss medications. Here’s the deal:

Normally, our guts release two hormones, GLP-1 and GIP, to tell our brains that we’re full and to regulate blood sugar. Tirzepatide acts like a master switch for both of these hormones. It activates the receptors for GLP-1 and GIP, which basically means it strengthens their messages.

This double action is what makes tirzepatide effective. Boosting both GLP-1 and GIP makes the body release more insulin, which helps control blood sugar. But more importantly, it makes people feel fuller for longer and reduces hunger. It’s like giving the body a one-two punch to manage weight – feeling satisfied and keeping blood sugar in check.

So, while the scientific terms might sound fancy, the key takeaway is that tirzepatide helps people feel fuller for longer and keeps blood sugar balanced, making weight management more achievable.

Who can benefit from these weight loss drugs?

Doctors generally recommend Mounjaro or Zepbound to people considered overweight, with additional weight problems such as diabetes, hypertension or hypercholesterolemia, or to people considered obese.

  • Generally: Wegovy is prescribed for adults with a Body Mass Index (BMI) of 30 or higher. This falls under the classification of obesity. BMI is a way to measure weight relative to height).
  • Weight-related health condition: If you have a BMI of 27 or more and a weight-related health condition, you might be prescribed Wegovy. Such conditions include high blood pressure, high cholesterol, or cardiovascular disease.

It’s important to talk to your doctor to see if these medications are right for you, considering your weight, health history, and other medications you might be takin

What are the differences between Ozempic/Wegovy (semaglutide) and Mounjaro/Zepbound (tirzepatide)?

Ozempic/Wegovy (semaglutide) and Mounjaro/Zepbound (tirzepatide) are both medications for blood sugar control and weight management, but they work slightly differently:

  • Ozempic/Wegovy targets one pathway (GLP-1) to help you feel full.
  • Mounjaro/Zepbound targets two pathways (GLP-1 and GIP) to increase fullness.

Ozempic and Wegovy are both based on semaglutide, the difference being in the maximum strength of a dose. Ozempic is prescribed for type 2 diabetes and delivers a maximum of 1 mg semaglutide each week in a single dose. Wegovy is prescribed for weight loss and can deliver up to 2.4 mg in a single weekly dose.

Mounjaro and Zepbound are both based on tirzepatide. Mounjaro is prescribed for type 2 diabetes and delivers a maximum dose of 7.5 mg tirzepatide, while Zepbound is prescribed for weight loss and delivers a maximum dose of 15 mg.
Each pen is calibrated to deliver the exact required dose.

How much weight can you lose with these medications?

Each person will respond differently to these medications, with many factors coming into play, such as the starting weight, how well you adhere to the exercise programs, and what you eat. Multiple studies (STEP for semaglutide and SURMOUNT for tirzepatide) came out with some averages. Over the 5+ years of the tirzepatide trial, 98.5% lost at least 5% of their starting body weight, 94% lost at least 10%, 87.1% lost at least 15%, and 72.6% achieved a 20% or higher weight loss.

This table shows the results of the studies:

What are the most common side effects of the weight loss meds?

Weight loss medications can come with some temporary side effects, like:

  • Stomach issues: This might include nausea, bloating, constipation, or diarrhea. These can be bothersome, but they usually get better over time as your body adjusts to the medication.
  • Less common side effects: Some people might experience headaches, fatigue, or dizziness—also, injection site reactions.

Side effects can vary between weight loss medications that are based on semaglutide or tirzepatide.

Most people who use weight loss medications do not experience any negative side effects. Doctors prescribe them because they assess the benefits of such treatment outweigh any likely unwanted effects.

Do you need to diet and exercise while taking these medications?

Yes. While these medications can be very helpful, they’re not magic pills.
Here’s the breakdown:

  • Diet and exercise are still super important. Think of it like this: the medications can help you feel fuller and reduce cravings, but they won’t magically make you eat healthy or crave vegetables. A balanced diet with healthy choices is key.
  • Exercise helps you build muscle. When you lose weight, you will also be losing some muscle. Exercise, especially strength training, helps you keep that muscle, which keeps your metabolism strong and helps you burn more calories.

So, even though medications like Wegovy and Tirzepatide can give you a boost, healthy eating, and exercise are your best friends for long-term weight management and overall health.

How long can you take these medications?

These medications are still pretty new. Ozempic only came out in 2017, so there haven’t been any long-term studies (yet!). The good news is, so far, there isn’t anything to suggest that either Wegovy or Zepbound cannot be taken for a long time as long as they’re working well and the person taking them isn’t having any problems.

Of course, the treating doctor will monitor the situation and adjust the plan as needed. Depending on your situation, they might recommend breaks or switching medications.

Some have reported that people who stop taking Wegovy or Zepbound will regain some of the lost weight. This is called the “rebound effect”. However, it is no different from what happens if a person loses weight while on a strict diet and then suddenly returns to eating normally. In such a case, weight regain is also seen.

So far, if there is a need to stop using the medications, the best way to maintain weight loss is to reduce the doses slowly and stick to the diet and exercise regimes that were adhered to during the treatment. In such cases, people who have come off these medications have been able to keep the weight off.

What is weight loss rebound after losing weight?

Weight loss rebound is a term used to describe how people can regain some or all of their lost weight. It is not unique to treatment with weekly injectable weight loss medications; rather, it applies to what can happen when a person has lost a lot of weight on a program and then stops the program.

How much do weight loss medications cost?

IsraelPharm brings you these medications at steeply discounted prices, in line with our policy of providing brand and generic prescription medication at prices you can afford. The current price for a single month’s use is:

Medication Strength Price
Ozempic 0.5 mg / 1.0 mg $485
Wegovy 1.7 mg $575
Wegovy 2.4 mg $625
Mounjaro 2.5 mg / 5 mg / 7.5 mg / 10 mg $750


Can I switch from Ozempic to Wegovy?

You might be able to switch from Ozempic to Wegovy, but only with your doctor’s approval. Here’s why:

  • Both have semaglutide: Wegovy and Ozempic actually contain the same medication, semaglutide. However, Wegovy comes in higher doses specifically for weight management.
  • Dosage matters: Because Wegovy has higher doses, your doctor will need to consider the Ozempic dose you were on and determine the best starting point for Wegovy.
  • They have different purposes: Ozempic is approved for type 2 diabetes, while Wegovy is for weight management. Your doctor will consider your individual needs.

So, while switching is possible, it’s not a simple yes or no answer. Talk to your doctor to see if Wegovy is the right fit for you and discuss the best way to transition.

Can I start on Ozempic and then move to Wegovy for stronger doses?

Ozempic is indicated for type 2 diabetes.
Wegovy is indicated for weight loss with a BMI over 28

Treatment with Wegovy and Ozempic starts at 0.25 mg per week for the first month, up to 0.5 mg in month two, and 1 mg in month three. Depending on progress and the doctor’s recommendation, one might stay at 1 mg for several months. The next dosage jump is 1.7 mg and can plateau there or take one more step up to the maximum dose of 2.4 mg.

Ozempic is available in doses of 0.25 mg, 0.5 mg, and 1 mg.

What is the difference between compounded and brand medication?

Due to worldwide shortages of weight loss medications caused by a surge in demand, pharmacies across the US have stepped up to ensure their customers can still access the necessary medications. One way they achieve this is through a process called compounding.

In a controlled environment, qualified pharmacists can combine ingredients to create the prescribed medicine using components available on their shelves. Semaglutide and tirzepatide can be formulated to match the strength of brand-name medications prescribed by doctors. Brand medications like Ozempic, Wegovy, and Mounjaro are produced by large corporations that initially developed these drugs and hold FDA approval for exclusive marketing under their brand names.

While active ingredients, such as semaglutide and tirzepatide, are not branded or patent-protected, the pharmacist must be properly qualified and trained to combine these ingredients to accurately meet the customer’s needs. You can have high confidence that you are getting the right medicine at the correct strength when you buy from a registered US pharmacist, that IsraelPharm works with.

How long does it take to start losing weight on Wegovy and Zepbound?

Here’s the deal on weight loss with Wegovy and Zepbound:

  • It takes some time: You might not see the scale budge right away. It can take a few weeks to feel a difference in your appetite due to the medication.
  • Slow and steady wins the race: For most people, weight loss becomes noticeable within a couple of months.
  • Patience is key: Studies show that on average, people taking these medications lose around 5% of their body weight after three months. It can take a year or more to reach your weight loss goals.

Remember, these medications work best alongside healthy eating and exercise. They can help you feel full for longer and reduce cravings, but they won’t replace healthy choices.

So, be patient and focus on making healthy changes for the long term. Talk to your doctor about your weight loss goals and what you can realistically expect.

Are weight-loss medications covered by insurance?

Currently, most insurance companies do not include coverage for Wegovy or Zepbound, but they do cover Ozempic and Mounjaro when used to treat diabetes. Medicare is not allowed to cover weight loss medications at this time. Some employer insurance plans are beginning to consider adding coverage for weight loss treatments due to the impact of weight-related illnesses on the workforce. To know for sure, it is best to check with your insurer.

Is body mass index the only way to judge whether I am a candidate for weight loss medication?

Body Mass Index (BMI) is the most common way of objectively measuring the degree of obesity in adults. It is a simple calculation based on weight (mass) and height. The formula for BMI is weight in kilograms (kg) divided by height in meters (m) squared. Adults with a BMI above 25 but below 30 are classified as overweight, and those with a BMI of 30 or higher are classified as obese.

Doctors use BMI because it is a simple and universally accepted measure. However, doctors have complete discretion in deciding whether a patient is or isn’t overweight. Some doctors prefer to use the waist/hips ratio as a better predictor of chronic health problems.

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