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For visual reference only; actual product may vary
For visual reference only; actual product may vary
Contrave is a prescription weight-loss medication combining Naltrexone and Bupropion. It helps adults who are obese, or overweight with related health issues, manage their weight by reducing appetite and cravings. This FDA-approved treatment is used alongside a diet and exercise plan for best results.
| Mysimba Brand | 90/8mg 112 Tablets |
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Our price: $233.00 |
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| Contrave Brand | 90/8mg 120 Tablets |
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Our price: $429.00 |
Contrave is a prescription medication approved by the FDA to help adults with obesity, or who are overweight with weight-related medical problems, to lose weight and keep it off. It is a combination of two active ingredients, naltrexone and bupropion, in an extended-release tablet. Contrave is designed as part of a comprehensive weight management program that includes a reduced-calorie diet and increased physical activity. It is not intended for cosmetic weight loss or to treat depression, though one of its components is an antidepressant.
Contrave works by combining two medications, naltrexone and bupropion, which target parts of the brain involved in regulating appetite, cravings, and reward pathways. Bupropion acts on the hypothalamus, an area of the brain that helps control hunger, to decrease your appetite. Naltrexone works on the mesolimbic dopamine pathway, which is your brain’s reward system. By doing so, it helps control the cravings and the pleasurable feelings you get from eating certain foods. This dual action helps you feel less hungry and reduces food cravings, making it easier to stick to your diet and lose weight.
Contrave is intended for adults aged 18 and over who have a body mass index (BMI) of 30 or greater (obesity), or a BMI of 27 or greater (overweight) along with at least one weight-related health condition like high blood pressure, type 2 diabetes, or high cholesterol. This medication is not suitable for everyone. It should not be used by individuals with uncontrolled hypertension, a seizure disorder, or an eating disorder like anorexia or bulimia. It is also contraindicated for patients taking opioids or who are pregnant.
Contrave treatment begins with a gradual dose increase over four weeks to reach the full maintenance dose, which helps minimize potential side effects. Your doctor will instruct you to start with one tablet each morning for the first week, then increase the dose weekly until you reach the full maintenance dose of two tablets twice a day by week four. The tablets must be swallowed whole and should not be cut, chewed, or crushed. Importantly, you should not take Contrave with high-fat meals, as this can increase your risk of seizures. If you miss a dose, skip it and wait for your next scheduled dose.
The most common side effects of Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, and dry mouth. These effects are often mild and may decrease as your body adjusts to the medication. However, Contrave also carries warnings about more serious risks due to its active ingredients. Bupropion has been linked to an increased risk of suicidal thoughts. Both ingredients can increase the risk of seizures, especially if taken with a high-fat meal or if you have certain predispositions. It can also increase blood pressure and heart rate. You must not take opioids while using Contrave due to the risk of overdose or withdrawal.
IsraelPharm offers a reliable and convenient way to purchase Contrave at competitive prices, backed by a team of experienced pharmacists and a commitment to global health standards. We provide access to authentic, brand-name medications sourced from regulated suppliers, ensuring you receive the same Contrave prescribed by your doctor. Our streamlined online ordering process, dedicated customer support, and discreet shipping to your door make managing your prescription simple and stress-free. Trust IsraelPharm for affordable healthcare delivered with expertise and care.
Most people taking Contrave experience minimal side effects, but some may occur. The most common ones often lessen over time. Always consult your doctor for medical advice about side effects.
Common side effects may include:
Serious side effects are rare but require immediate medical attention. These include:
This is not a complete list. Discuss all potential risks with your healthcare provider.
Contrave is a prescription medication used for chronic weight management in adults, in combination with a reduced-calorie diet and increased physical activity. It is specifically indicated for individuals who are:
You may start to notice a decrease in your appetite within the first few weeks of taking Contrave. However, the full impact on your weight can take longer to become apparent. Your doctor will typically evaluate your progress after 12 to 16 weeks on the full dose to determine if the medication is effective for you.
You should avoid or strictly limit consuming alcohol while taking Contrave. Combining alcohol with Contrave can increase your risk of having a seizure, which is a rare but serious side effect associated with the bupropion component. It is very important to discuss your alcohol use with your doctor before you start this medication.
If you miss a dose of Contrave, you should skip the missed dose entirely and take your next dose at the regular scheduled time. You should not take an extra or double dose to make up for the one you missed. Taking more Contrave than prescribed can increase your risk of serious side effects, including seizures.
You should avoid taking Contrave with high-fat meals. A high-fat meal can significantly increase the drug levels in your blood, which raises your risk of seizures. You can take the tablets with other food or on an empty stomach, but always swallow them whole. Do not cut, crush, or chew the tablets.
Contrave contains bupropion, an antidepressant that carries a warning for an increased risk of suicidal thoughts and behaviors, particularly in children, teenagers, and young adults. All patients should be monitored for any unusual changes in mood, behavior, or thinking. Report any concerning changes to your doctor immediately.
No, you must not take Contrave if you are taking opioid medications or other drugs containing bupropion. Contrave contains naltrexone, which completely blocks the effects of opioids and can cause sudden withdrawal symptoms. It also increases the risk of an opioid overdose if you stop Contrave and resume opioid use.
The amount of weight you lose on Contrave can vary. In clinical studies, patients taking Contrave along with diet and exercise lost more weight than those using lifestyle changes alone. Your success depends on your consistent use of the medication combined with your commitment to a healthy diet and regular physical activity.
Contrave is not a stimulant and is not classified as a controlled substance. Unlike some other weight-loss medications that act as stimulants, Contrave works on the brain's appetite and reward centers. This means it has a lower potential for abuse or dependence compared to scheduled or controlled weight-loss drugs like phentermine.
Yes, Contrave is prescribed as part of a complete weight management plan that includes a reduced-calorie diet and regular exercise. The medication helps manage your appetite and food cravings, making it easier to adhere to these lifestyle changes. For the best results, these healthy habits are essential for long-term success.
The Contrave titration, or dose-escalation, is a four-week schedule. You begin with one pill daily and gradually add pills each week until you reach the full maintenance dose of two pills twice a day. This slow increase allows your body to get used to the medication and helps to minimize potential side effects like nausea.
You should store your Contrave tablets at room temperature, away from sources of high heat and moisture. Do not keep the medication in the bathroom, as the humidity can damage the pills. As with all prescription drugs, it is critical to keep Contrave in a secure location that is out of reach of children and pets.
Yes, Contrave can cause an increase in blood pressure and heart rate, which is why it should not be used by people with uncontrolled hypertension. Your doctor will check your blood pressure and pulse before you start and will monitor them periodically during your treatment to ensure they remain in a safe range for you.
When you stop taking Contrave, its effects on appetite control will cease. To maintain your weight loss, it is vital to continue the healthy diet and exercise habits you developed. Your doctor may advise you on how to stop the medication, but there is no specific tapering schedule required unless advised otherwise.
No, you must swallow Contrave tablets whole. You should never cut, chew, or crush them. Contrave is an extended-release tablet, and altering it can cause the medication to be released into your body too quickly. This is dangerous as it dramatically increases your risk of serious side effects, most notably seizures.
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