Vagifem – vaginal tablets (suppositories) are used to treat symptoms of menopause.
Vagifem® (estradiol) is a natural form of the female sex hormone estrogen. This medication can be used to treat menopause symptoms, but also for the reduction in urgency or irritation during urination.
Get emergency medical help if you have any of these signs of an allergic reaction: hives, difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects: chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; sudden numbness or weakness, especially on one side of the body, sudden headache, confusion, problems with vision, speech, or balance, pain, swelling, warmth, or redness in one or both legs, abnormal vaginal bleeding, pain, swelling, or tenderness in your stomach, jaundice (yellowing of the skin or eyes), or a lump in your breast.
Less serious side effects may include: Nausea, vomiting, loss of appetite, swollen breasts, acne or skin color changes, decreased sex drive, impotence, or difficulty having an orgasm, migraine headaches or dizziness, vaginal pain, dryness, or discomfort, swelling of your ankles or feet, depression, changes in your menstrual periods, break-through bleeding.
Treatment of Atrophic Vaginitis due to Menopause, Treatment of vaginal atrophy due to oestrogen deficiency in postmenopausal women
The experience treating women older than 65 years is limited.
Vagifem® is administered intravaginally as a local oestrogen therapy by use of an applicator.
Initial dose: One vaginal tablet daily for two weeks.
Maintenance dose: One vaginal tablet twice a week.
Treatment may be started on any convenient day.
If a dose is forgotten, it should be taken as soon as the patient remembers. A double dose should be avoided.
For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration should be used.
Vagifem® is a local vaginal therapy and in women with an intact uterus, progestagen treatment is not necessary
Special warnings and precautions for use – Endometrial hyperplasia and carcinoma.
Vagifem® may be used in women with or without an intact uterus.
Vaginal infections should be treated before the start of the Vagifem® therapy.
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