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Ozempic

Ozempic (semaglutide) will help control blood sugar levels in adults with type 2 diabetes. It has been approved for overweight adults to help them lose weight. Ozempic comes in a pen injector prefilled with four doses of the prescribed strength, to be used once each week.

Ozempic can only be shipped to the United States.

Maximum 1 pen per order.

Compounded Semaglutide is also available. Click here for more details. If your dose is higher than 1mg per week or you are looking for a more cost effective alternative, this is a great option.

Ozempic
Brand
1mg
1 Pen
$550.00
Ozempic
Brand
0.5mg
1 Pen
$550.00
Ozempic
Brand
0.25mg
1 Pen
$550.00

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Ozempic (generic name: semaglutide) is a medication designed to help control blood sugar levels (hyperglycemia) and also reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes. 

Ozempic is a glucagon-like peptide 1 (GLP-1) receptor agonist. GLP-1 is a hormone produced in the gut. It is released in response to food, prompting the release of insulin as well as a reduction in appetite. 

In the case of people with type 2 diabetes, it acts to slow digestion and, in this way, stimulates increased production of natural insulin. In this sense, Ozempic does not work like other treatments of diabetes, which provide the required insulin from external sources (injection or oral insulin). Some doctors do treat type 1 diabetes with Ozempic, but this is an off-label use and does not have FDA approval. Read more about off-label prescribing here.

For people who have been classified as overweight or obese, Ozempic may be prescribed as a weight-loss treatment along with appropriate diet controls and exercise. The primary effect of Ozempic in this treatment is as an appetite suppressant.

Special benefits provided by Ozempic

As well as its effectiveness in controlling blood-sugar levels without insulin, Ozempic acts to lower the levels of A1C. The hemoglobin A1C or HbA1c test measures average blood sugar levels over a period of 3 months. It is an effective test for diagnosis of prediabetes and tracking development of diabetes.

In a study of over 1200 adults treated with once-weekly Ozempic, patients that started with an average A1C of 8.1 reached an A1C less than 7 (the target for healthy blood sugar level) after twelve months.

Ozemic also lowers the risk of major events such as heart attack, stroke, or death in people with preconditions of cardiovascular disease.

Ozemic works to reduce appetite and feelings of hunger, which can, along with good diet and exercise programs, induce weight loss and to sustain weight reduction. GLP-1, the key hormone in Ozempic, reduces gastric emptying (the speed at which the stomach empties of food) and blocks production of glucagon, the hormone that instructs the liver to release stored glucose. Both of these will cause a reduction in the need for food intake.

Dosage and Administration

Usually, the dosage starts at 0.25 mg once weekly. After four doses, it will be increased to 0.5 mg each week. Possible further increases may be prescribed by your doctor at the end of each four weeks if the results indicate that higher doses are needed.

Ozempic is self-administered from the supplied kit containing a pre-filled pen with one month’s supply (four doses plus needles). The kit should be kept refrigerated.

It is advisable when you take the first dose to be under supervision, since there have been reports of a very small number of people suffering anaphylactic shock with the first administration of Ozempic. Your doctor or nurse should show you how to self-administer.

Ozempic should be administered once weekly on the same day and at the same time of day, with or without meals. If a dose is missed, administer one within five days of the skipped one, but do not double-dose! Ozempic should be injected just under the skin into the upper thigh, abdomen, or upper arm. Swap injection sites on a four-week cycle so that you are not injecting into the same area each week. At the very least, do not inject closer than 15 centimeters (6 inches) from the previous week’s site.

The FDA has also approved it for prescription to obese adults to help them lose weight. The administration is exactly the same as for diabetic patients. It is not used for the control of type 1 diabetes.

Before injecting, check that the Ozempic pen is clear and doesn’t contain any particles or discoloration. If it does, immediately replace that pen.

Do not share your Ozempic pen with other people, even if the needle has been replaced. The dosage in the pen has been calibrated for your personal requirements. You could also cause or receive a serious infection.

Always take the time to read the manufacturer’s Product Insert that comes with the medication. Not all side effects are listed here. Consult a healthcare provider if you experience any of these or other unexpected effects.

The reported side effects associated with all GLP-1 treatments are:

  • Risk of pancreatitis
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Constipation

Generally, these are mild and should clear within a few weeks of the commencement of treatment. However, if they persist, or worsen, consult with the prescribing physician immediately. You can read more about the possible side effects here

While it is not known that Ozempic will cause thyroid tumors, consult with the prescribing physician if you have trouble swallowing, hoarseness, shortness of breath, or notice a lump or swelling in your neck. These could be symptoms of thyroid cancer.

The benefits from usage of Ozempic are:

  • Improved glycemic control in adults with type 2 diabetes
  • Reduced risk of adverse cardiovascular events in adults with type 2 diabetes who have pre-existing cardiovascular disease
  • Weight reduction.

Dosage and Administration

Usually, the dosage starts at 0.25 mg once weekly. After four doses, it will be increased to 0.5 mg each week. Possible further increases may be prescribed by your doctor at the end of each four weeks if the results indicate that higher doses are needed.

Ozempic is self-administered from the supplied kit containing a pre-filled pen with one month’s supply (four doses plus needles). The kit should be kept refrigerated.

It is advisable when you take the first dose to be under supervision, since there have been reports of a very small number of people suffering anaphylactic shock with the first administration of Ozempic. Your doctor or nurse should show you how to self-administer.

Ozempic should be administered once weekly on the same day and at the same time of day, with or without meals. If a dose is missed, administer one within five days of the skipped one, but do not double-dose! Ozempic should be injected just under the skin into the upper thigh, abdomen, or upper arm. Swap injection sites on a four-week cycle so that you are not injecting into the same area each week. At the very least, do not inject closer than 15 centimeters (6 inches) from the previous week’s site.

The FDA has also approved it for prescription to obese adults to help them lose weight. The administration is exactly the same as for diabetic patients. It is not used for the control of type 1 diabetes.

Before injecting, check that the Ozempic pen is clear and doesn’t contain any particles or discoloration. If it does, immediately replace that pen.

Do not share your Ozempic pen with other people, even if the needle has been replaced. The dosage in the pen has been calibrated for your personal requirements. You could also cause or receive a serious infection.

  • How do I use Ozempic?

    Ozempic comes in a pre-loaded pen with four doses. Take care to read the instruction leaflet that comes with each pen. Twist the loader at the back of the pen clockwise as far as it will go, and inject just under the skin in either the abdomen or thigh. Try to rotate the injection site each week (for example, left abdomen, left thigh, right abdomen, right thigh), so that you do not inject at the same place twice in a row. Ozempic is taken once each week. It is best to take it on the same day of the week and at about the same time.
  • How does Ozempic work for diabetes?

    Ozempic is designed to control blood sugar levels for people with type 2 diabetes who are not producing sufficient insulin or who are not processing insulin correctly (hyperglycemia). Ozempic has the effect of increasing insulin sensitivity while inhibiting glucose production in the liver. Ozempic is different from other treatments of diabetes, which provide insulin from external sources (injection or oral insulin).
  • Does Ozempic come in pill form?

    The generic component in Ozempic is semaglutide. It is also available as an oral medication known as Rybelsus. The prescribing doctor will decide which drug best suits each person’s specific needs.
  • How much will a one-month supply of Ozempic cost?

    Buying a one-month supply of Ozempic from IsraelPharm currently costs $550, regardless of the strength
  • How many doses of Ozempic are in one pen?

    Each Ozempic pen has exactly four doses calibrated to match your doctor's prescription strength.
  • What are the alternatives to Ozempic?

    Ozempic contains the GLP-1 receptor agonist known as semaglutide. It increases insulin secretion and lowers blood sugar levels by improving glycemic control. There may be other options or alternatives, which can be discussed with the prescribing healthcare practitioner.
  • What is the difference between Ozempic and semaglutide?

    Semaglutide is the generic name of the drug that is contained in Ozempic. Ozempic is a brand name.
  • Can Ozempic expire?

    Like all drugs, Ozempic has an expiry date printed on the package. It should not be used beyond that date. Ozempic should be stored in temperature-controlled conditions, preferably in a refrigerator, before the pen is used.
  • How long do you take Ozempic for diabetes?

    Type 2 diabetes is not curable. Everyone who has been diagnosed with diabetes should be under regular supervision by a healthcare professional and should continue the prescribed medications as long as they are needed. Treatments aim to either reduce sugar levels in the blood with diet or boost insulin levels directly with oral or injected insulin or, like Ozempic, to stimulate the natural secretion of insulin.
  • What type of diabetes does Ozempic treat?

    Ozempic treats type 2 diabetes - sometimes called diabetes mellitus. The main differences between type 1 and type 2 diabetes are the typical age of onset, and the cause. Type 1 diabetes often starts in very young patients, and has a very strong hereditary pattern. Only 8-10% of all cases are type 1. Type 2 diabetes develops over many years, and although there are some genetic tendencies, it is mostly brought on through lifestyle and diet. Some doctors do treat type 1 diabetes with Ozempic, but this is an off-label use and does not have FDA approval.
  • How long does it take for Ozempic to start working?

    Some results of using Ozempic can usually be seen within two weeks of starting the medication. However, this may be different for some people depending on how the body responds to it. The full benefits of Ozempic should show for most people after twelve weeks.
  • What happens after you stop taking Ozempic?

    It would be best if to not stop or change treatment for type 2 diabetes without discussing this with a healthcare provider. Diabetes is not curable, and as soon as medication for this conditionis stopped or there is a change off a sugar-controlled diet, there can be a rapid return of hypoglycemia. With proper supervision, it may be possible to reduce dosages of Ozempic, but this must be done only under the supervision of a doctor.
  • Does Ozempic work for the first time?

    Most doctors follow the recommended path: start dosages of Ozempic at the lowest level (0.25 mg each week) for the first month, then gradually step up each month until the total dose of 1 mg is reached. There may only be a slight improvement in sugar levels over this period, so it is essential to closely monitor blood sugar levels and consult regularly with a doctor.
  • What should I do if I miss a dose of Ozempic?

    Doctors recommend that if a scheduled dose of Ozempic is missed, it should be made up as soon as possible, but at most five days late. If more than five days have passed, it is better to skip the missed dose. In either case, stick to the original weekly schedule.
  • Can anyone get Ozempic for weight loss?

    Ozempic is not yet approved by the FDA for weight loss, and is mostly used to treat people with diabetes. Many doctors are now prescribing Ozempic for patients who are seriously overweight or obese. The criteria are for the patient to have a bods mass index (BMI) of 30 or higher, or BMI of 27 if there are associated conditions (such as diabetes, high blood pressure or sleep apnea.)
  • Is it legal for doctors to prescribe Ozempic off-label for overweight patient?

    Doctors are the only ones who can decide the proper treatment for a patient. They are best placed to choose the appropriate treatment. Off-label prescribing is entirely legal and is very common in medical practice. About one-fifth of all prescriptions in the US are for off-label use. Doctors can prescribe Ozempic for patients who are overweight or obese.
  • What are Ozempic’s side effects?

    The reported side effects associated with Ozempic are gastric upsets like nausea, vomiting, diarrhea, abdominal pain, flatulence or constipation. Generally, these are mild and should clear within a few weeks of the commencement of treatment. However, if they persist, or worsen, consult with the prescribing physician immediately. While it is not known that Ozempic will cause thyroid tumors, consult with the prescribing physician if you have trouble swallowing, hoarseness, shortness of breath, or notice a lump or swelling in your neck. These could be symptoms of thyroid cancer.
  • How long will I have to stay on Ozempic?

    When Ozempic is used to treat long-term type 2 diabetes, it may be prescribed by a healthcare practitioner for continuous use, since diabetes is not curable. When it is prescribed for weight loss, other factors can influence the strength and length of treatment, and the prescribing doctor will adjust the administration based on response to the medication, any changes in health, or if new medications are being prescribed. A person’s condition should be closely monitored throughout treatment, and a doctor can stop treatment or adjust the dosage as needed.
  • Can I drink alcohol when taking Ozempic?

    Although there haven’t so far been any specific studies on whether alcohol has any adverse effects when a person is taking Ozempic, it is known that people with type 2 diabetes should not drink alcohol other than very moderately and infrequently. This subject needs to be discussed with the prescribing healthcare provider.
  • Does Ozempic interact with other food or drugs?

    Ozempic can interact with other medications. Make sure that the prescribing doctor is fully aware of all medications being taken, including supplements and herbal preparations. Ozempic doesn’t have any known interactions with food.
  • Are there warnings about using Ozempic?

    Healthcare practitioners are aware of the possible dangers of drugs they prescribe, and would only issue a prescription if they judge that the benefits of the medication outweigh the risks. If you have any questions, be sure to discuss this with the prescribing doctor before starting treatment.
  • Who should not take Ozempic?

    Doctors would typically not prescribe Ozempic for a patient with a history of thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2. People with medical conditions like liver or kidney problems, heart disease, diabetes, or epilepsy should ensure that the prescribing doctor is fully informed of all of these.
  • What can happen if you take too much Ozempic?

    Overdosing on Ozempic can cause hypoglycemia (low blood sugar levels) and some other serious side effects, such as allergic and injection site reactions. There are also some infrequent risks of thyroid tumors or pancreatitis. Following the prescribing doctor’s instructions about frequency and dosage is essential.

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Understanding off-label prescribing

Off-label prescribing is the term that applies when a medical practitioner prescribes medication for a purpose or condition other than what it has been  approved for by the US Food and Drug Administration (FDA). Off-label

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