Wegovy (generic name: semaglutide) is a glucagon-like peptide 1 (GLP-1) receptor agonist. Wegovy is prescribed together with a moderate program of dieting and exercise for people who have been classified as overweight or obese. The primary effect of semaglutide in this treatment is as an appetite suppressant.

GLP-1 is a hormone produced in the gut after a meal. It prompts the release of insulin as well as slowing down the passage of food through the stomach. This induces a feeling of satiety, which has the effect of postponing the desire for another meal. GLP-1 also targets receptors in the brain that control appetite, resulting in less craving for food. Eating less food can reduce body weight.

Dosage

The dosage regime is set by the prescribing doctor. Wegovy is self-administered by a weekly injection. The usual process for a new regime is to administer steadily increasing strengths until the full dosage is reached. For example begining with 0.25 mg per week in the first 4 weeks, then increasing to 0.5 mg in weeks 5 through 8,  1 mg in the weeks 9 through 12, and 1.7 mg from week 13. Where the full dosage is 2.4 mg, this will start from week 17. Once the full dose has been reached, the same dosage continues for as long as the prescribing healthcare professional allows.

It may be possible to get the prescribing doctor to substitute Ozempic for Wegovy in the initial phases. Ozempic is identical to Wegovy, but has a maximum strength of 1 mg. This makes it a cheaper alternative to Wegovy for the first 3 months.

It is important to read the Patient Information leaflet carefully before starting using this medicine. It contains specific guidelines on how Wegovy should be administered.

Storage

After purchase, Wegovy must be stored in the refrigerator at temperatures between 2°C to 8°C (36 to 47°F). It must not be frozen or allowed to come into contact with the cooling element in the refrigerator.  Do not use Wegovy if it has been frozen!

A pen can be kept for maximum of six weeks at temperatures below 30°C/86°F if it is going to be administered within six weeks. If the solution is not clear and colourless, the pen should be disposed of. As well, keep Wegovy out of reach of babies and children. Please read our  tips on handling medicine safely

Frequently asked questions

What are the differences between Wegovy and Ozempic?

Although both Wegovy and Ozempic share the same active ingredient they serve different purposes. Wegovy is promoted for weight management and heart disease prevention whereas Ozempic is primarily used to manage type 2 diabetes. Ozempic has FDA approval for treating adults with type 2 diabetes and lowering the risk of diseases in this population.

Can Wegovy be used for losing weight?

Wegovy is an injectable medication designed for adults who are obese (with a BMI of ≥30) or overweight (with a BMI of ≥27) and have weight related health issues. Its purpose is to aid in weight loss efforts while following a reduced calorie diet plan and increasing activity levels.

How much weight can you shed in three months with Wegovy?

When it comes to shedding pounds, using medications like Wegovy that target GLP 1 receptors can lead to rapid weight loss. In three months most individuals can anticipate losing, over 5% of their current body weight.