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For visual reference only; actual product may vary

  • US Name:

    Xeljanz

  • Alternative Names:

    Xeljanz

  • Active Ingredients:

    Tofacitinib citrate

  • Brand Manufacturer:

    Pfizer

  • Manufacturer Location:

    Turkey

  • Click here to view Product Insert

  • Click here to view Product Insert

Xeljanz

For visual reference only; actual product may vary

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Xeljanz (tofacitinib) is a targeted oral therapy for adults with autoimmune conditions. It effectively reduces joint pain and inflammation from rheumatoid or psoriatic arthritis. It also treats ulcerative colitis and other inflammatory diseases. Xeljanz helps manage symptoms when other treatments have failed, including off-label use for alopecia.

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Xeljanz XR
Brand
11mg
28 Tablets
$479.00 Add to Cart
Xeljanz
Brand
5mg
56 Tablets
$512.00 Add to Cart

What is Xeljanz?

Xeljanz is a prescription medication used to treat several chronic autoimmune diseases in adults. Its generic name is tofacitinib. It belongs to a class of drugs known as Janus kinase (JAK) inhibitors. Xeljanz is primarily approved for moderately to severely active rheumatoid arthritis and psoriatic arthritis. It is also used for ulcerative colitis and ankylosing spondylitis. Doctors often prescribe it when older treatments, like TNF blockers, were not effective. Additionally, Xeljanz is used off-label to treat hair loss from alopecia areata.

How does Xeljanz work?

Xeljanz works by inhibiting the activity of Janus kinase (JAK) enzymes inside your cells. These enzymes play a key role in the inflammation that causes symptoms in autoimmune disorders. By blocking these specific pathways, Xeljanz interrupts the signaling process that leads to an overactive immune response. This action helps to calm the immune system. It reduces inflammation, leading to less pain, swelling, and stiffness in the joints. For ulcerative colitis, it helps decrease inflammation and damage in the colon lining.

Who is Xeljanz for?

Xeljanz is intended for adults with specific autoimmune diseases who need a targeted treatment. It is suitable for patients with rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, or ankylosing spondylitis. It is often a next step for those who did not respond well to or could not tolerate TNF blocker medications. Xeljanz can also be an option for people with severe alopecia areata. This medication is not for everyone. It should not be used by people with active serious infections, severe liver problems, or very low blood counts. Pregnant or breastfeeding women should also avoid it.

Dosage and administration

Xeljanz should be taken exactly as prescribed by a healthcare provider. It comes as an oral tablet that you can take with or without food. Your specific dose and whether you take it once or twice daily depends on your condition and the formulation prescribed (immediate-release or extended-release). Do not crush, split, or chew extended-release tablets. Always follow the instructions on your prescription label. Store the medication at room temperature, away from moisture and heat. Keep it safely out of the reach of children.

Side effects

Xeljanz may cause some side effects, though not everyone experiences them. The most common side effects include upper respiratory tract infections, headaches, and diarrhea. While usually mild, you should tell your doctor if these persist. Xeljanz also has a risk of more serious side effects due to its effect on the immune system. These include serious infections like tuberculosis and shingles, an increased risk of blood clots, and certain types of cancer. Your doctor will monitor you closely with regular blood tests to check for changes in your blood cells and cholesterol levels.

Why buy from IsraelPharm?

IsraelPharm offers a reliable and convenient way to get your prescription medications. We source our products from a highly regulated and secure supply chain, ensuring you receive authentic Xeljanz at a competitive price. Our platform makes it easy to order online with a valid prescription from your doctor. With discreet packaging and international shipping, we bring your medication right to your door. Our customer service team is available to assist you with any questions, providing a seamless and trustworthy experience for all your pharmacy needs.

Xeljanz can cause side effects, which range from mild to serious. It is important to be aware of potential reactions while taking this medication.

Common Side Effects:

These effects are generally mild and may decrease over time. Contact your doctor if they persist.

  • Upper respiratory tract infections (common cold, sinus infections)
  • Headache
  • Diarrhea
  • Nasal congestion or sore throat

Serious Side Effects:

Xeljanz includes warnings about serious risks. Seek immediate medical attention if you experience any of the following:

  • Serious Infections: Symptoms may include fever, chills, cough, fatigue, or painful skin rash (shingles). There is an increased risk of tuberculosis and fungal infections.
  • Blood Clots: Signs include sudden chest pain, shortness of breath, or pain and swelling in a leg.
  • Cancer and Lymphoma: Xeljanz may increase the risk of developing certain cancers.
  • Low Blood Counts: Your doctor will monitor your blood cell levels.
  • Gastrointestinal Perforations: Tears in the stomach or intestines.

Xeljanz is approved to treat adults with several chronic inflammatory and autoimmune conditions, particularly when other treatments like TNF blockers have not been effective.

Approved Indications:

  • Rheumatoid Arthritis: For moderately to severely active cases, reducing joint pain and swelling.
  • Psoriatic Arthritis: For active cases, helping with joint inflammation and skin plaques.
  • Ulcerative Colitis: For moderately to severely active cases, managing inflammation in the large intestine.
  • Ankylosing Spondylitis: For active cases, targeting inflammation in the spine.

Common Off-Label Uses:

  • Alopecia Areata: To promote hair regrowth by calming the immune attack on hair follicles.
  • Other Rheumatic Diseases: Including dermatomyositis and systemic lupus erythematosus.

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