Frequently Asked Questions about Motilium
The internet is full of frequently asked questions about Motilium. It is a popular drug for the treatment of common gastric problems that’s no longer available in the US. In this post, we’ll try to answer as many questions as we can. And, let you know that Motilium is in fact still available from us for quick delivery.
What’s Motilium used for?
Motilium (generic name: domperidone) is used to treat nausea and vomiting and certain gastrointestinal problems like gastroparesis. The drug increases the motility in the digestive system. As a result, food that passes through the stomach is quickly moved towards the intestines, thus preventing its return and vomiting.
Originally, Motilium was also prescribed as a lactose-boosting medication for breast-feeding mothers. However, when negative side effects were reported, its FDA approval was withdrawn. This only affected availability in the USA, and the drug is still widely approved and available in other countries.
It can be prescribed to treat nausea and vomiting in adults and adolescents over twelve years of age and weighing 35 kilos (80 pounds) or more. Normal dosage is for a maximum of 4-7 days, at the discretion of the prescribing doctor.
Motilium can be used to relieve nausea and gastrointestinal symptoms in Parkinson’s disease, especially for patients who cannot tolerate some of the side effects of the regular medications. Nausea and vomiting is a major problem for people with Parkinson’s. That’s because most medications used to treat it, such as Stalevo and Sinemet, are taken orally and can cause nausea as a side effect. Other anti-nausea drugs, such as Pramin, may worsen the extrapyramidal symptoms of Parkinson’s disease. That’s because they do cross the blood–brain barrier in normal doses, so they have no effect on these symptoms.
What is in the drug?
Motilium’s main active component is domperidone, which is a dopamine antagonist medication. A dopamine antagonist is a type of medication that works by blocking the action of dopamine. Dopamine is a neurotransmitter (a chemical messenger in the brain) that plays a role in regulating mood, movement, and other functions in the body.
Dopamine antagonists are often prescribed as an off-label option to treat psychiatric conditions such as schizophrenia and bipolar disorder. It’s also prescribed to alleviate nausea and vomiting in conditions such as chemotherapy-induced nausea, morning sickness, and motion sickness. They may also be used to treat other conditions such as migraine headaches, hiccups, and certain movement disorders.
By blocking dopamine receptors in the brain and gut, dopamine antagonists such as domperidone can help reduce nausea and vomiting. As well, it can improve gastric emptying and relieve symptoms of bloating and discomfort. However, because dopamine is also involved in other functions in the body, such as regulating heart rate and blood pressure, dopamine antagonists can also have other effects such as changes in heart rhythm and blood pressure, as well as movement disorders and other neurological symptoms.
How is the medicine supplied?
Motilium is available in 10 mg strength tablet form.
There are three packages of 10 mg tablets, supplied by us as follows:
|Generic – Apo||500 Tablets||$258.00|
|Generic – Teva||100 Tablets||$55.00|
|Brand – Janssen Cilag||21 Tablets||$14.00|
Why was Motilium taken off the market?
In 2004, the FDA ordered US pharmacies to pull Motilium off their shelves. It was because of some concerns regarding potential serious health risks coming with the use of domperidone by lactating women to enhance their breast milk production. Some of the reported side effects were cardiac arrhythmias, cardiac arrest, and even mortality.
These reported risks have only been associated with use of Motilium as a boost for lactation in breastfeeding mothers. There have been no major side effects when Motilium is being used for treatment of gastrointestinal disorders.
Motilium is still available under prescription in many other countries, including from us in Israel.
Is Motilium available overseas?
Yes, Motilium is available in many countries overseas like Israel, and is commonly prescribed for the treatment of nausea, vomiting, and other gastrointestinal conditions.
Is Motilium good for anxiety?
While Motilium is primarily used to treat nausea and vomiting, there is some evidence to suggest that domperidone may have anxiolytic (anti-anxiety) effects as well. However, this use is off-label and not officially approved by regulatory authorities, including the FDA in the United States.
There have been a few small studies that have explored the potential anxiolytic effects of domperidone. For example, a study published in the Indian Journal of Psychiatry in 2016 found that domperidone, when used in combination with a benzodiazepine, was more effective in reducing anxiety symptoms in patients with generalized anxiety disorder than the benzodiazepine alone. Another study published in the Journal of Psychopharmacology in 2014 found that domperidone was effective in reducing anxiety-like behavior in rats.
However, it’s important to note that these studies are small and have limitations, and further research is needed to fully understand the potential anti-anxiety effects of domperidone. Additionally, domperidone is not typically used as a first-line treatment for anxiety and should only be prescribed for this purpose after careful consideration of the risks and benefits, as well as other available treatment options.
Does Motilium work for stomach bugs?
Motilium may help alleviate symptoms of a stomach bug, such as nausea and vomiting, but it is not specifically approved for this purpose.
Does Motilium help with acid reflux?
Motilium may help relieve symptoms of acid reflux by speeding up stomach emptying, but it is not specifically approved for the treatment of acid reflux.
What are the dangers of Motilium?
The main but very rare dangers of Motilium include potential cardiac side effects, such as QT prolongation and arrhythmias, which can increase the risk of serious and sometimes fatal heart rhythm problems. Incidences of these are extremely rare.
Why is Motilium not FDA approved?
Motilium is not FDA approved for use in the United States due to concerns about its side effects on breast-feeding mothers. There have been no major side effects on other users, and it’s still widely available in other first-world countries, like the UK, EU, Australia and Israel.
Is Motilium legal in the US?
Domperidone is not currently approved for use in the US and is not approved for importation or distribution for personal use. However, doctors can still prescribe it off-label when they feel that the benefits outweigh any associated risks for their patients. IsraelPharm can supply Motilium when it’s been prescribed by your doctor.
Can you get Motilium in the United States?
Motilium is not available directly from pharmacies in the United States, but it may be available through special access programs for patients with certain medical conditions. It can be prescribed off-label by US physicians, and we are able to supply such orders ourselves.
Is Motilium available in the US?
No, Motilium is not currently available directly in the US, but can be sourced from us when prescribed by your doctor.
What is the alternative to domperidone in the USA?
There are several alternatives to domperidone in the US, including other medications such as Pramin (metoclopramide) and Zofran (ondansetron), which may be used to treat similar conditions.