Metoclopramide is commonly used to treat nausea and vomiting associated with conditions such as uremia, radiation sickness, cancer and the effects of chemotherapy, labor, infection, migraine headaches, and emetogenic drugs. In the setting of painful conditions such as migraine headaches, metoclopramide may be used in combination with paracetamol (acetaminophen) or in combination with aspirin. It is also used preventatively by some EMS providers when transporting people who are conscious and spinally immobilized.
Side effects of Pramin
- Drowsiness;
- Fatigue, tiredness;
- Anxiety, restlessness, agitation;
- Trouble sleeping;
- Diarrhoea, constipation, bowel irregularities;
- Headache, dizziness;
- Breast enlargement, unusual secretion of breast milk.
Metoclopramide is an antiemetic and stimulates GI motility.
Pramin is indicated in adults for:
- Prevention of postoperative nausea and vomiting (PONV)
- Prevention of delayed nausea and vomiting caused by chemotherapy (delayed CINV)- Prevention of nausea and vomiting caused by radiation therapy
- Symptomatic treatment of nausea and vomiting, including nausea and vomiting caused by migraine attack. In migraine attacks, metoclopramide can be used concomitantly with oral analgesics to improve their absorption.
- Diabetic gastroparesis Pediatric population
Pramin is indicated in children aged 1 to 18 years for
- Second line-therapy: Treatment of established postoperative nausea and vomiting (PONV)
- Second-line therapy: Prevention of delayed nausea and vomiting caused by chemotherapy (delayed CINV)