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  • US Name:

    Denosumab Brand

  • Alternative Names:

    Denosumab Brand

  • Active Ingredients:

    Denosumab

  • Brand Manufacturer:

    Brand

  • Manufacturer Location:

    Netherlands

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Denosumab Brand *

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Denosumab Brand is prescribed to treat osteoporosis in people with prostate or breast cancer, bone loss that results from a reduction in testosterone, or systemic glucocorticoids therapy with prednisone.

 

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Denosumab Brand 60mg
1 Vial
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Our price: $480.00

*Please note all prices are in US dollars
Denosumab Brand (generic name: denosumab) is a human monoclonal antibody for the prevention of bone loss (osteoporosis) in postmenopausal women and in men who have a reduction in testosterone levels caused by surgery or treatment. It is also prescribed to prevent bone fractures in people with prostate or breast cancer who are undergoing treatment or with bone loss associated with long-term systemic glucocorticoid therapy with prednisone, where they are expected to remain on glucocorticoids for at least three months.

Caution

Women of childbearing age should use a barrier method of contraception while being treated with Denosumab Brand and for at least five months after stopping treatment. In case you become pregnant during treatment with Denosumab Brand or within five months after stopping treatment, please inform your doctor.

Dosage

Denosumab Brand is administered by professional healthcare providers. The recommended dosage is one dose administered once every six months as a single subcutaneous injection. Please follow the doctor’s instructions when ordering, and read the information in the manufacturer’s product leaflet that comes with the medication. Denosumab can carry serious health risks.

Storage

After receipt of the dose, it must be stored in the refrigerator at temperatures between 2°C/36°F and 8°C/47°F if it is not going to be administered within 30 days. Immediately before administration, it should be brought to room temperature (up to 25°C/77°F). As well, keep Denosumab Brand out of reach of babies and children. Please read our friendly tips on handling medicine safely

This text is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

Possible side effects of Denosumab include:

  • bone, joint, or muscle pain which can be severe
  • upper respiratory tract infection
  • constipation
  • back pain
  • muscle pain
  • pain in the arms and legs
  • anemia
  • diarrhea
  • hair loss (alopecia)
  • skin problems such as rash, itching, redness or eczema.

While taking Denosumab, there may be a greater likelihood of a severe infection, such as a skin, ear, stomach/gut, or bladder infection.

Inform a doctor immediately if there are signs of infection while taking the medication, such as:

  • fever/chills, night sweats
  • red/swollen/tender/warm skin
  • severe stomach or abdominal pain
  • ear pain or drainage, trouble hearing
  • frequent/painful/burning urination, or pink/bloody urine
  • severe itching, burning, rash, blistering, peeling, or dryness of the skin
  • cough or shortness of breath
  • pinpoint purple or red spots under your skin
  • flu symptoms
  • weight loss

Not all possible side effects can be listed here. If you experience any of these or other unexpected side effects, consult a healthcare provider immediately.

Denosumab Brand is a form of the generic drug denosumab that has been approved for the reduction of the risks of bone fractures in people with:

  • Postmenopausal osteoporosis
  • Osteoporosis in men treated with surgery or medication for prostate cancer with resulting androgen deprivation
  • Bone loss associated with long-term systemic glucocorticoid therapy
  • Bone loss in women with breast cancer due to aromatase inhibitor-induced estrogen depletion (low estrogen levels)

Postmenopausal women and men with reduced levels of testosterone have an increased risk of spinal, non-spinal, and hip fractures.

  • Can Denosumab Brand rebuild bone?
    In clinical trials, Denosumab Brand was shown to help strengthen bone and increase bone mass. It also helped to reduce the incidence of vertebral, nonvertebral, and hip fractures in postmenopausal women with osteoporosis.
  • When should the use of denosumab be avoided?
    It may be suggested to avoid the use of Denosumab during pregnancy as denosumab may cause some harm to a fetus. Advising the prescribing doctor of the possibility of pregnancy during the course of treatment is very important. Denosumab Brand has been reported as causing a severe condition of the jaw bone known as osteonecrosis of the jaw (ONJ). If dental surgery or treatment is scheduled while receiving this medication, the responsible healthcare professional should be informed in advance that this medication is currently being used.
  • What precautions are necessary when being treated with denosumab?
    The prescribing doctor should be aware of all other medications being taken (including over-the-counter drugs, vitamins, or herbal remedies). It’s crucial to not take aspirin or products containing it unless the doctor is aware and permits it.
  • Is pregnancy allowed while being treated with denosumab?
    The prescribing healthcare professional must be made aware before starting this treatment if you are pregnant or planning to become pregnant. Use of denosumab is permitted only if the benefit to the mother outweighs the risk to the fetus. Otherwise, both men and women should avoid conception while taking denosumab. The use of barrier methods of contraception, such as condoms, is recommended.
  • Is denosumab allowed while breastfeeding?
    It is not yet known whether denosumab is excreted into human milk. Because there may be a potential for severe adverse reactions in infants from denosumab, the decision should be to either discontinue nursing or discontinue the drug while taking into account the importance of denosumab to the mother.

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