Gynoflor (generic name: Estriol and Lactobacillus) is a vaginal tablet formulated to address specific gynecological conditions. It combines estriol, a natural estrogen hormone, with Lactobacillus, a probiotic bacteria. Estriol helps restore hormonal balance by compensating for estrogen deficiency, particularly in postmenopausal women. Lactobacillus, on the other hand, promotes a healthy vaginal flora by maintaining an optimal pH (acidic level)and preventing harmful bacterial overgrowth.

This combination is primarily prescribed for the treatment of atrophic vaginitis, a condition characterized by thinning and inflammation of the vaginal walls due to reduced estrogen levels which is typical in menopause. Additionally, it supports the regeneration of the vaginal epithelium and replenishment of the natural microbiota, creating a protective environment against infections. Gynoflor belongs to the pharmacological class of hormone-replacement therapies combined with probiotics.

For further details on estriol-based therapies and their applications, refer to this overview.

Dosage

The typical dosage of Gynoflor involves the insertion of one tablet daily into the vagina, ideally at bedtime, for an initial period of 6 to 12 days. Afterward, the dosage may be reduced to one tablet twice a week for maintenance, depending on the patient’s response and the physician’s recommendations.

It is important to insert the tablet gently into the vaginal canal. If a dose is missed, it should be taken as soon as remembered, unless it is close to the next scheduled dose. Doubling doses should be avoided to prevent complications.

Storage

Gynoflor requires refrigeration to maintain the viability of the Lactobacillus cultures. Store it in a refrigerator between 2°-8°C (36°-46°F) but do not freeze. Ensure it is kept away from direct sunlight. Once opened, it is advised to use the medication within the period specified by the manufacturer to maintain effectiveness.

Common Questions About Gynoflor

Can Gynoflor treat bacterial vaginosis?

Gynoflor is not a primary treatment for bacterial vaginosis but can help restore healthy vaginal flora after infections or antibiotic therapy.

How long should Gynoflor be used?

The duration depends on the condition being treated. A typical course is 6-12 days, followed by fortnightly maintenance. Always follow the doctor’s advice.

Can Gynoflor be used during pregnancy?

Its use during pregnancy is not standard and should be evaluated by a healthcare provider based on potential risks and benefits.