Spend $99, get free U.S. shipping*

Important Update: We’re open, but due to the security situation in Israel, some delays in shipping and customer support are expected.
We’ll keep things moving as best we can. Thanks for standing with us.

For visual reference only; actual product may vary

  • US Name:

    Efudix, Efudex

  • Alternative Names:

    Efudix Cream, Efudix Oint

  • Active Ingredients:

    Flourouracil

  • Brand Manufacturer:

    ICN pharma

  • Manufacturer Location:

    Germany

  • Click here to view Product Insert

  • Click here to view Product Insert

Efudix, Efudex *

For visual reference only; actual product may vary

Prescription Required
All third-party products, company names, and logos are trademarks™ or registered® trademarks are and remain the property of their respective holders. Their use does not imply any affiliation with or endorsement by them. All references on this site to third-party trademarks are intended to constitute nominative fair use under applicable trademark laws.

Efudex / Efudix Cream is used to treat skin growths and pre-cancerous conditions such as actinic keratoses and superficial basal cell carcinomas.

Place your order

Efudix Cream Brand 5%, 20gm
1 Tube
-
+
Our price:
$80.00

*Please note all prices are in US dollars

Efudex / Efudix Cream (generic name: fluorouracil) is a topical medication used to treat skin growths and pre-cancerous conditions such as actinic keratoses and superficial basal cell carcinomas.

Fluorouracil belongs to the class of anti-cancer agents known as pyrimidine analogues, which act by mimicking the building blocks of DNA. When applied to the skin, fluorouracil interferes with the synthesis of DNA in rapidly growing abnormal cells, causing them to die and eventually slough off. This interference stops abnormal skin cells from multiplying and causes them to die, allowing healthy skin to regenerate.

Efudex is primarily indicated for treating actinic keratoses, a skin condition caused by long-term exposure to ultraviolet radiation. Actinic keratoses typically appear as rough, scaly patches on sun-exposed areas of the body such as the face, scalp, and arms. These patches may remain flat or become raised and are considered pre-cancerous, with the potential to progress to squamous cell carcinoma if left untreated.

In addition to pre-cancerous lesions, Efudex is also used to manage certain types of superficial basal cell carcinoma, a common form of skin cancer that often occurs on areas of the body exposed to the sun. These lesions tend to grow slowly and may present as open sores, red patches, or shiny bumps. By targeting the abnormal cells at a molecular level, Efudex aids in their removal and encourages the replacement of damaged tissue with normal skin.

Because Efudex acts on the DNA of rapidly dividing cells, it is highly selective in targeting skin areas where abnormal cell growth is present. The medication is commonly used in dermatologic treatment plans as a non-surgical approach for managing early-stage skin abnormalities. Its use helps reduce the burden of visible and microscopic lesions that may not yet be apparent but are developing beneath the skin’s surface.

This treatment is not recommended for pediatric use. Patients with some metabolic conditions may be at increased risk for adverse responses and are typically evaluated before treatment is initiated.

Caution

Women who are pregnant or breastfeeding are advised to avoid the medication due to the potential risk of harm to the fetus or nursing infant. If pregnancy occurs while using Efudex, consult with a healthcare provider immediately.

Dosage

Follow the prescribing doctor’s dosage instructions which are printed on the label. Check with a doctor or pharmacist if there are any doubts regarding the proper dosage and treatment regimen.

Efudex Cream 5% is typically applied externally to affected skin once or twice daily for 3 to 4 weeks. Treatment should be limited to areas no larger than about 23 x 23 cm (9 x 9 inches) per session. A thin layer of cream is spread across the damaged skin using clean hands, and hands should be washed thoroughly afterward unless they are the treated area. Avoid covering treated areas with tight bandages or dressings, as this can increase skin irritation.

If a dose is missed, the cream should be applied as soon as remembered unless it is near the time for the next scheduled dose. In that case, skip the missed application and continue as normal. Do not apply extra amounts to compensate.

If accidental ingestion occurs or the cream gets into the eyes or mouth, rinse the area immediately and seek medical attention.

Storage

Store Efudix Cream at temperatures below 30 °C / 80 °F. Keep the tube tightly closed and protected from heat and light. Use the cream within three months of opening; record the opening date on the package.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication. 

Read the information leaflet that comes with the medication.

Most people who use Efudix / Efudex do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.

Some of the side effects that have been reported include redness, swelling, burning, itching, crusting, erosion, and discomfort in treated skin areas. These responses are expected and show that the cream is working. The skin may peel or form scabs during treatment.

Occasionally, serious reactions can occur, such as ulceration, blistering, extensive inflammation beyond treatment areas, or severe pain. Patients should seek immediate medical care if they experience persistent burning, swelling, fever, or signs of infection (e.g., oozing, increased redness).

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Efudex Cream is approved for treating actinic keratoses, which appear as rough, scaly patches caused by prolonged sun exposure. Common symptoms include dry, rough texture, redness, itching, or burning sensation on affected skin. These lesions have the potential to develop into squamous cell carcinoma, making treatment important.

The cream is also used for superficial basal cell carcinoma (BCC). BCC typically appears as pink or flesh-colored patches that may bleed or remain open, often occurring on sun-exposed areas like the face. Treatment with Efudix helps destroy these abnormal cells without the need for surgery in certain cases.

Off-label use can include treating other superficial skin cancers or sun-damaged areas. Patients using Efudex should receive regular skin checks from a dermatologist to monitor treatment effects and detect any new or recurring lesions.

  • Efudex targets abnormal skin cells by interfering with their DNA, causing them to die off and revealing healthy skin underneath. This process helps eliminate rough, scaly patches before they can develop into skin cancer. The skin may appear inflamed at first, which is an expected sign that the treatment is working. Over time, treated areas heal as healthy cells replace the damaged ones.

Getting started with IsraelPharm

Required

Send Your Prescription

Secure Payment

No Hidden Fees

Fast Shipping

Generally 7-10 Business Days

Fast delivery
Secure payment
Genuine brands
Pharmacist oversight
Proudly Israeli

Ordering is
simple and safe.

IsraelPharm has been delivering lost cost prescriptions from Israel for over 15 years worldwide. Daily flights allow us to get your medications dispatched fast! Delivery to the USA is under 10 days and you can track and trace every order.

Read more from our blog

Go Red for Women Heart Health

Go Red for Women Heart Health

In 2004, the American Heart Association (AHA) recognized a critical issue: cardiovascular diseases were claiming the lives of countless women in the United States each year, but the problem was largely unnoticed by the public.

Read More »

Login

Fast Delivery
Ships from Israel
Secure Payment
Genuine Brands
Pharmacist Oversight
Proudly Israeli
Free Shipping on orders over $99*

Having issues?

Daily from 9am-8pm EST.
IsraelPharm c/o SUBS Ltd. Ha'Uman 5 Bet Shemesh Israel, 9906105

Sign up for $10 off your first order!

Enjoy exclusive deals we only share via email