Free shipping on orders over $99*

Tel: 1-866-456-3768  Fax: 1-866-544-8993



  • US Name:


  • Generic Names:

    Trimix, Tri-Mix

  • Active Ingredients:

    Papaverine, Phentolamine, Prostaglandin E1

  • Brand Manufacturer:

    Custom Compound

  • Manufacturer Location:


  • Click here to view Product Insert

  • Click here to view Product Insert

  • Click here to view Product Insert


Prescription Required

Tri-Mix is prescribed to treat erectile dysfunction. It is custom compounded for each order based on the specific instructions from the physician.

Place your order

Tri-Mix Generic Various Strengths
1 mL
Our price: $120.00

*Please note all prices are in US dollars
Tri-mix is a compounded medication containing papaverine, phentolamine and alprostadil (prostaglandin E1) that can be injected directly into the penis to achieve erection for men who have erectile dysfunction.
Compounding medicines is a specialized practice where pharmacists create customized medications tailored to the specific needs of an individual patient. Tri-mix combines three chemicals to create a medication that meets the precise requirements of a prescription. Papavarine is a smooth muscle relaxant and vasodilator. Phentolamine causes blood vessels to expand, which increases blood flow. Alprostadil also acts as a smooth muscle relaxant and dilator of blood vessels. The three chemicals combine to create a more effective treatment for erectile dysfunction than each one individually.


Only use Tri-mix as prescribed. Usually, doctors will administer the first dose themselves, so that the proper use of the injectable can be demonstrated. The dose should be injected slowly into the base of the penis, allowing 5 to 10 seconds for it to be completely injected.  This will increase blood flow to the two hollow chambers (corpus caversnosa) that lie along the length of the shaft and results in an erection.
Do not inject more than once each day, more than two days in a row, or more than three times in one week, without first consulting with a doctor.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication. 

Most people who use the components of Tri-mix do not experience any negative side effects. Doctors prescribe Tri-mix because they assess that the benefits that such treatment yields outweighs any likely unwanted effects.

Most of the side effects that have been reported are transient and do not need medical attention, such as bruising or bleeding at the site of the injection, mild swelling at the place of injection, or difficulty ejaculating. See more about the side effects coming from alprostadil here.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.


Tri-mix is a new medication for the treatment of erectile dysfunction in adult men. Erectile dysfunction is defined as the persistent inability to achieve or maintain an erection sufficient for sexual intercourse through to orgasm.

It is a common condition that can affect men of all ages, and which has been found to affect more than one half of all men between the ages of 40 and 70, with the incidence increasing with age

  • Does Tri-mix work better than Caverject and Viagra?
    Caverject contains just alprostadil. Tri-mix contains alprostadil as well as papaverine and phentolamine. All three of these have a combinatorial effect, and produce full erections for more men than the three drugs can on their own. Viagra is an oral medication that only works for men who have some residual erectile function, whereas Tri-mix can produce an erection whether spontaneous erections are possible or not.
  • How long do erectile dysfunction injections last?
    Doctors adjust the dose and strength according to a patient's specific needs. With the use of Tri-mix, it has been established that an erection will normally be achieved within 10 minutes of the injection, and will last for between 30 minutes and one hour.
  • Are injections better than pills for erectile dysfunction?
    The choice of oral or injectable medication for treating erectile dysfunction can only be made by a doctor. Before choosing injectables, doctors will usually try one or more of the oral medications, but switching to injectables will be an option if the pills did not prove satisfactory, or caused unwanted side effects. Injectables may be the only choice if a man has no spontaneous erectile function.
  • Are compounded medications safe?
    The effects and effectiveness of compounded medications are generally the same as their mass-produced counterparts when prepared by reputable compounding pharmacies that can be relied on to ensure quality and safety.

Getting started with IsraelPharm


Send Your Prescription

Secure Payment

No Hidden Fees

Fast Shipping

Generally 7-10 Business Days

Fast delivery
Secure payment
Genuine brands
Pharmacist oversight
Proudly Israeli

Ordering is
simple and safe.

IsraelPharm has been delivering lost cost prescriptions from Israel for over 15 years worldwide. Daily flights allow us to get your medications dispatched fast! Delivery to the USA is under 10 days and you can track and trace every order.

Read more from our blog

close up of medical pills in a pill box on table
drug safety

Tips to prevent medication mishaps

As pharmacists, ensuring our patients understand proper medication use is part of our DNA. We empower them to manage their medications effectively once they leave our pharmacy. This drives our efforts to make sure that


Fast Delivery
Ships from Israel
Secure Payment
Genuine Brands
Pharmacist Oversight
Proudly Israeli
Free Shipping on orders over $99*

Having issues?

Daily from 9am-8pm EST.
IsraelPharm c/o SUBS Ltd. Ha'Uman 5 Bet Shemesh Israel, 9906105

Sign up for $10 off your first order!

Enjoy exclusive deals we only share via email