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  • US Name:

    Trelegy Ellipta

  • Generic Names:

    Trelegy Ellipta

  • Active Ingredients:

    Fluticasone & Umeclidinium & Vilanterol

  • Brand Manufacturer:


  • Manufacturer Location:


  • Click here to view Product Insert

  • Click here to view Product Insert

Trelegy Ellipta

Prescription Required

Trelegy Ellipta is a 3-in-1 inhaler for long-term treatment of asthma  and COPD.  It is not intended to treat sudden attacks of breathing problems, for which a quick-acting rescue inhaler should be used.

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Trelegy Ellipta (30 doses) Brand 184/55/22
1 Inhaler
Our price: $237.00
Trelegy Ellipta (30 doses) Brand 92/55/22
1 Inhaler
Our price: $142.00

*Please note all prices are in US dollars
Trelegy Ellipta is a medication that contains three active ingredients: fluticasone, umeclidinium, and vilanterol. Trelegy Ellipta is used as a maintenance medication for asthma and moderate to severe chronic obstructive pulmonary disease (COPD). It helps to keep the airways less reactive and reduces the frequency and severity of asthma attacks. Fluticasone belongs to a class of medications known as inhaled corticosteroids (ICS). It works by reducing swelling and inflammation in the airways of the lungs, which are often inflamed in people with asthma and COPD. This drug helps to prevent and control symptoms like difficulty breathing, chest tightness, wheezing, and coughing. Bronchodilators like umeclidinium and vilanterol are medications used to help people with asthma and COPD. Umeclidinium is a long-acting muscarinic antagonist (LAMA). Vilanterol is a long-acting beta2-adrenergic agonist (LABA). They help to widen the air passages (bronchodilation), making it easier for individuals with asthma and COPD to breathe and reduce the symptoms of bronchoconstriction. Trelegy Ellipta inhaler comes in two strengths. Trelegy Ellipta 92/55/22 in Israel is the equivalent of 100/62.5/25 in the US. Trelegy Ellipta 184/55/22 in Israel is the equivalent of 200/62.5/25 in the US. It is intended for long-term maintenance treatment of asthma in patients aged 18 years and older who can’t be adequately controlled on other maintenance asthma medication. Trelegy Ellipta is not intended to relieve acute breathing problems caused by asthma. Trelegy Ellipta inhaler in the 92/55/22 mcg strength is intended for the maintenance treatment of moderate to severe chronic obstructive pulmonary disease (COPD) in adults who can’t be treated by other medications. This medicine is not intended for children or adolescents below the age of 18 years.


Trelegy Ellipta should be used every day as prescribed. It should not be used to relieve a sudden attack of breathlessness or wheezing brought on by an asthma attack or other symptoms of COPD. In such instances, it is necessary to use a quick-acting rescue inhaler (such as Ventolin). The recommended dosage for asthma and COPD is one inhalation of Trelegy Ellipta each day at the same time. The medicine’s effects last for 24 hours. Do not exceed the recommended dose. If you forgot to inhale the medicine at the required time, do not inhale twice to compensate for the forgotten dose. Inhale the usual dose at the proper time. If you become wheezy or breathless, use your rescue inhaler (such as salbutamol) and seek medical advice.

The information here is for informational purposes only. Please consult your doctor or pharmacist before using Trelegy Ellipta.  

Please read the manufacturer’s Product Insert that comes with the medication. Not all side effects are listed here. Consult a healthcare provider if you experience these or other unexpected effects.

One of the side effects reported in COPD patients is the development of pneumonia following a common cold. Consult with your physician if you have any of the following symptoms using Trelegy Ellipta, as these could be symptoms of a lung infection:

  •     Fever or chills
  •     Increased mucus production or change in mucus color
  •     Increased cough or increased breathing difficulties.

Other common side effects include:

  •     Sore, raised patches in the mouth or throat caused by a fungal infection (candidiasis).
  •     Infection of the nose, sinuses or throat
  •     Infection of the upper airways
  •     Itchy, runny, or blocked nose
  •     Pain in the back of the mouth and throat
  •     Inflammation of the sinuses
  •     Inflammation of the lungs (bronchitis)
  •     Flu (influenza)
  •     Headache
  •     Cough
  •     Hoarseness.

If these persist or worsen, consult with a healthcare provider.

If you experience either of the following reactions immediately after using the Trelegy Ellipta inhaler, stop using the medicine and seek medical help immediately, as you may have a serious condition:

  •     Tightness of the chest, coughing, wheezing or breathlessness (may be signs of paradoxical bronchospasm).
  •     Eye pain or discomfort, temporary blurring of vision, seeing halos or colored images, and red eyes (may be signs of an acute attack of narrow-angle glaucoma).

Asthma is a condition that inflames and narrows (broncho constricts) the lungs’ airways. It can lead to difficulty breathing and impaired lung function. Symptoms are sporadic, including shortness of breath, wheezing, chest tightness, and cough.

Chronic obstructive pulmonary disease (COPD) is characterized by breathing difficulties. It is a long-term condition that slowly gets worse. In COPD, the muscles around the airways tighten, making breathing difficult.

This medicine widens the muscles in the lungs, reduces the swelling and irritation in the small air passages, and makes it easier for air to pass in and out of the lungs. Regular use can help control breathing difficulties and reduce the effects of COPD.

  • What happens if you drink water after using an inhaler?
    Users of a corticosteroid inhaler such as Trelegy Ellipta should gargle and rinse out their mouth with water immediately after use. It is advisable not to swallow the water since that will increase the chance that the medicine will get into the bloodstream and increase the likelihood of side effects.
  • What are the long-term effects of steroid inhalers?
    If taking a high dose for a long time, there is a slight chance of some of the same side effects as steroid tablets. These include increased appetite, mood changes and insomnia. Taking high doses for a long time has been shown to affect the growth of children and teenagers.
  • Can Trelegy affect your voice?
    The corticosteroid (fluticasone) in Trelegy Ellipta is reported to cause hoarseness (dysphonia) as a fairly common side effect.
  • How long should you wait to eat or drink after using an inhaler?
    The inhaler should be used at least one hour before eating. Afterward, eating slowly while sitting up can ease pressure on the lungs and help them expand more easily.
  • Is Trelegy bad for your heart?
    Trelegy Ellipta has been reported to cause some heart problems, including a rapid pulse and high blood pressure. The risk is higher for people with a history of heart problems or high blood pressure. Medical attention should be sought immediately if there is any chest pain or a fast or irregular heartbeat.

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