Savella ^*

Savella may begin to improve fibromyalgia symptoms within the first one to two weeks of treatment. However, it can take up to a month or longer for you to feel the full therapeutic benefits. The exact timeline varies for each person. Consistent daily use as prescribed by your healthcare provider is essential to achieve the best results for pain and fatigue reduction.

Savella can cause liver damage, and drinking alcohol may increase this risk. It is strongly recommended to limit or avoid alcohol consumption while taking this medication. Combining alcohol with Savella might also worsen side effects like dizziness and drowsiness. Always consult your doctor about alcohol use to ensure your safety and the effectiveness of your treatment plan.

Savella is not an opioid or a narcotic. It belongs to a class of drugs called serotonin-norepinephrine reuptake inhibitors (SNRIs). Unlike opioids, Savella is not considered to have a high potential for addiction. It works by changing the levels of neurotransmitters in the brain to manage pain perception, rather than blocking pain signals like opioid medications do.

Savella can affect individuals differently. While it aims to reduce fatigue from fibromyalgia, some people may feel drowsy. Conversely, others might experience insomnia. If you experience significant fatigue, discuss it with your doctor. They may adjust your dosing schedule or suggest other strategies to manage this effect. This ensures the treatment remains effective for you.

You should not stop taking Savella abruptly, as this can lead to withdrawal symptoms. These symptoms may include dizziness, anxiety, nausea, headache, and electric shock-like sensations. Your doctor will provide a plan to gradually decrease your dose over time to minimize these effects. This tapering process ensures your body can adjust safely. Always follow medical advice when discontinuing this medication.

Savella can be taken with some other pain medications, but you must consult your doctor first. Combining Savella with NSAIDs (like ibuprofen) or blood thinners can increase the risk of bleeding. Taking it with other antidepressants or triptans can lead to a serious condition called serotonin syndrome. Your doctor will review all your current medications to prevent harmful interactions.

Savella is not commonly associated with significant weight gain. In clinical trials, weight changes were not a prominent side effect, with some patients even reporting slight weight loss. However, medication effects can vary from person to person. If you notice any significant changes in your weight, you should discuss them with your healthcare provider to monitor your health properly.

Savella is typically prescribed to be taken twice daily, once in the morning and once in the afternoon. Taking it at the same times each day helps maintain a consistent level of the medication in your body. Because it can sometimes cause insomnia, it is generally not recommended to take the second dose too close to bedtime. Your doctor will give you specific instructions.

Savella should be stored at room temperature, between 68°F to 77°F (20°C to 25°C). Keep the medication in its original container, tightly closed, and away from moisture, heat, and direct sunlight. It is also important to store Savella in a safe place where children and pets cannot access it to prevent accidental ingestion.

Savella is not approved by the FDA for the treatment of depression in the United States. Its primary approved use is for the management of fibromyalgia. While the active ingredient, milnacipran, is approved for depression in some other countries, using Savella for depression in the US is considered an off-label use. This must be supervised by a healthcare professional.

Savella is generally not recommended for use during pregnancy unless the potential benefit justifies the risk to the fetus. Taking this medication during the third trimester may increase the risk of complications for the newborn. If you are pregnant or planning to become pregnant, it is crucial to discuss the risks and benefits with your doctor to make an informed decision.

If you miss a dose of Savella, you should take it as soon as you remember. However, if it is almost time for your next scheduled dose, you should skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time to make up for a missed one, as this can increase your risk of side effects.

Savella can cause an increase in both blood pressure and heart rate. Your doctor will likely monitor your blood pressure before you start treatment and periodically while you are taking the medication. If you have a history of hypertension or heart problems, it is especially important to discuss this with your doctor. They will determine if Savella is a safe option.