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Hydroxychloroquine is used to treat rheumatoid arthritis, It is a disease-modifying anti-rheumatic drugs (DMARDs)

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Unlike painkillers, DMARDs work in rheumatoid arthritis by suppressing the excessive activity of the immune system that causes the inflammation of the joints. This actually slows progression of the underlying disease. It is not fully understood how hydroxychloroquine works, but it reduces the inflammation in the joints and the associated swelling and pain . However, it doesn’t reverse any structural damage to the joints that has already occurred. DMARDs are used when painkillers called non-steroidal anti-inflammatory drugs do not provide sufficient relief from the pain of the arthritis. However, unlike NSAIDs, they can take up to six months to produce their full effect, so they don’t provide immediate relief from the pain.

Common side effects may include:
headache, dizziness, ringing in your ears;
nausea, vomiting, stomach pain;
loss of appetite, weight loss;
mood changes, feeling nervous or irritable;
skin rash or itching; or.
hair loss.Plaquenil is contraindicated in: • patients with pre-existing maculopathy of the eye • Hypersensitivity to the active substance or to any of the excipients listed in section 2. • in the presence of retinal or visual field changes attributable to any 4-aminoquinoline compound • long-term therapy in children • children under 6 years of age.

Plaquenil is indicated for the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, p. malaria. p. ovale and susceptible strains of p. falciparum. It is also indicated for the treatment of discoid and systemic lupus erythematosus and rheumatoid arthritis

  • What conditions can DMARDs treat?

    Palqenil belongs to the group of drugs known as disease-modifying antirheumatic drugs (DMARDs). This is a group of medications frequently used to treat people with rheumatoid arthritis. Some of these drugs can also be prescribed to treat other conditions, including ankylosing spondylitis, systemic lupus erythematosus and psoriatic arthritis.
  • What drugs slow down rheumatoid arthritis?

    Rheumatoid arthritis (RA) is believed to be incurable, but there are drugs available, like Palquenil, that research has shown can often slow down the rate of deterioration or even stop RA from getting worse. It interrupts the immune processes, which promote inflammation. It may take up to six months before the total effect is felt.
  • How do you reduce the side effects of DMARDs?

    The advice generally is to schedule taking DMARDs after eating so there will be less feeling of nausea. General advice is to avoid drinking alcohol both immediately before and for several hours after taking the dose of Palquenil. Many doctors advise that folic acid supplements can ease nausea and reduce mouth sores and liver problems.
  • What is the success rate of DMARDs?

    Clinical tests of treatment with DMARDs and biologics have shown that remission rates can exceed sixty percent. The rate of remission is also dependent on catching the symptoms early so that treatment can be started as soon as possible.
  • How long does it take for DMARDs to start working?

    DMARDs have a high rate of benefit for most people. They may take six weeks to three months to start to produce benefits. The main action of DMARDS in inflammatory arthritis is to shut down the inflammatory processes, and this can take a long time.


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