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  • US Name:

    Pentasa, Canasa

  • Israeli Names:

    Pentasa, Pentasa SR, Rafasal

  • Active Ingredients:

    Mesalamine 5Asa

  • Brand Manufacturer:


  • Manufacturer Location:


Pentasa, Canasa

Mesalazine is a type of medicine called an aminosalicylate. It is used to reduce inflammation in the intestines in a condition called ulcerative colitis.

Prescription Required
1 gr
28 Suppositories
1 gr SR
60 Tablets
Pentasa SR
1 gr SR
100 Granules
Pentasa SR
500mg SR
100 Tablets
1gr Cap
30 Capsules
4gr Enema
7 Bottle
500mg Caps
60 Caplets
*Please note all prices are in US dollars

Pentasa (generic: mesalamine 5-ASA) affects a substance in the body that causes inflammation, tissue damage, and diarrhea. Mesalamine is used to treat ulcerative colitis, chron’s, proctitis, proctosigmoiditis and other inflammatory bowel diseases. Mesalamine is also used to prevent the symptoms of ulcerative colitis from recurring.

Pentasa Side Effects by Likelihood and Severity
Inflammation Of The Tissue Lining The Sinuses.
Stomach Cramps.

Treatment of mild to moderate ulcerative colitis and Crohn’s disease

  • Is mesalamine a steroid?

    Pentasa and Canasa (mesalamine 5-ASA) do not have the same action as steroids. The designed effect of mesalamine is to reduce swelling and inflammation in the gut so as to treat inflammatory bowel disease, including ulcerative colitis. That is also what some steroids, such as Prednisone, are meant to do. Pentasa belongs to a separate class of medication known as aminosalicylates.
  • Is mesalamine the same as aspirin?

    Mesalamine 5-ASA is a chemical derivative of aspirin (acetylsalicylic acid). It has been reformulated to act in the large intestine. It is meant to provide an anti-inflammatory effect that should help to heal the lesions caused by colitis and Crohn’s Disease that are responsible for symptoms. Aspirin itself doesn’t provide any relief in cases of ulcerative colitis and may actually aggravate it.
  • What happens when you stop Pentasa?

    Symptoms may worsen if the prescribed medication is suddenly stopped. If there are unexpected side effects or a lack of relief of the symptoms, it should be discussed with a doctor or pharmacist as soon as possible. The medication should be continued even if symptoms start to recede, and changes should only be undertaken under the guidance of a medical practitioner.
  • Should Pentasa be taken in the morning or night?

    The schedule should be discussed with the prescribing healthcare provider with further input from a pharmacist. They should be taken at the same time each day. The extended-release capsules of Pentasa can be taken with or without food. The granules should be taken from the sachet straight onto the tongue and washed down with water or juice whole without chewing or crushing. After inserting a suppository, it’s advisable to lie or sit still for roughly fifteen minutes, allowing the suppository to soften from body heat.
  • What to avoid when taking mesalamine?

    Exposure to intense ultraviolet light, such as from sunlamps and tanning beds, should be avoided since this medicine can create serious unwanted skin reactions, especially if there are preexisting skin problems like atopic dermatitis or atopic eczema. Common OTC antacids can counteract the wanted effect of Canasa by inhibiting the amount of the drug that is released. If any dental or surgical procedures are due, it is essential to inform the doctor or dentist that mesalamine is being taken.


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