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For visual reference only; actual product may vary

  • US Name:

    Osphena

  • Alternative Names:

    Osphena

  • Active Ingredients:

    Ospemifene

  • Brand Manufacturer:

    Duchesnay

  • Manufacturer Location:

    Canada

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Osphena *

For visual reference only; actual product may vary

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Osphena is a selective estrogen receptor modulator used to treat vaginal dryness caused by vulvar and vaginal atrophy in postmenopausal women.

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Osphena Brand 60mg
30 Tablets
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Our price:
$90.00

*Please note all prices are in US dollars
Osphena (generic name: ospemifene) is a selective estrogen receptor modulator (SERM) used to treat vaginal dryness caused by vulvar and vaginal atrophy (VVA) in postmenopausal women. These symptoms result from reduced estrogen levels, leading to vaginal tissue thinning and increased discomfort. One of the main results of VVA is moderate to severe dyspareunia (pain during sexual intercourse.)

Osphena works by mimicking estrogen’s effects on vaginal tissues, increasing their thickness and reducing fragility. This helps relieve pain and discomfort during intercourse. Unlike traditional hormone replacement therapies, Osphena is a non-hormonal oral treatment.

Clinical studies have demonstrated Osphena’s effectiveness in improving vaginal tissue health and alleviating related symptoms. However, it is not suitable for all women, and risks such as increased blood clot risk should be discussed with a healthcare provider.

Dosage

The usual recommended dose is one 60 mg tablet taken orally once daily with food. Consistency is important. Take the tablet at the same time each day. If a dose is forgotten, take it as soon as remembered unless it’s almost time for the next dose. Do not double-dose to make up for a missed dose.

Storage

Store Osphena at room temperature (20°-25°C / 68°-77°F). Keep it in the original packaging to protect from heat, moisture and light.

Common Questions About Osphena

How long does Osphena take to work?

Some women notice improvements within a few weeks, but full benefits may take up to 12 weeks. Results vary depending on individual health factors.

Can I take Osphena with other medications
Some medications, including estrogen therapies and blood thinners, may interact with Osphena. Always consult a healthcare provider before combining medications.
What causes vulvar and vaginal atrophy (VVA)?
VVA occurs when estrogen levels drop after menopause, causing thinning, dryness, and inflammation of vaginal tissues. This leads to pain during intercourse and daily discomfort.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication. 

Read the information leaflet that comes with the medication.

Most people who use Osphena do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.

Some of the side effects that have been reported include hot flashes, vaginal discharge, muscle spasms, and excessive sweating.

Less common side effects are increased risk of blood clots, stroke, or uterine cancer. Seek immediate medical attention for symptoms like chest pain, shortness of breath, or leg swelling or any unusual vaginal bleeding.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Osphena is FDA-approved for treating symptoms associated with vulvar and vaginal atrophy (VVA) in postmenopausal women, including:

  • Moderate to severe dyspareunia (pain during intercourse)

    • Caused by thinning vaginal tissues due to estrogen decline.
    • Osphena helps restore vaginal tissue thickness, reducing pain.
  • Vaginal dryness
    • Leads to irritation, burning, and discomfort in daily activities.
    • Osphena improves vaginal moisture and elasticity.

Some doctors may prescribe Osphena off-label for other menopausal symptoms. Osphena is not for use in pregnant or breastfeeding women.

  • Is Osphena a hormone replacement therapy (HRT)?
    No, Osphena is not a traditional hormone replacement therapy (HRT). It is a selective estrogen receptor modulator (SERM) that mimics estrogen’s effects only in vaginal tissues.
  • Does Osphena cause weight gain?
    Weight gain is not a common side effect, but some women may experience bloating or water retention. Discuss any concerns with your doctor.
  • Can Osphena treat other menopausal symptoms?
    Osphena is only approved for vaginal atrophy symptoms and does not treat hot flashes, mood swings, or osteoporosis. Other treatments may be needed for those symptoms.
  • Is Osphena safer than traditional estrogen therapy?
    Osphena is a non-hormonal treatment, making it a safer alternative for some women who cannot take traditional estrogen therapy. However, it still has risks, such as blood clots and uterine cancer.
  • Can Osphena be used long-term?
    Long-term use should be evaluated by a doctor, as risks may increase over time. Regular medical checkups are essential to monitor for potential side effects

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