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OTC: No Prescription Required

Optalgin is an over-the-counter medication used to treat pain and fever

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Optalgin (dipyrone) can be used to relieve moderate to severe pain such as headaches, toothache, and menstrual pain. It can also be used to reduce high fevers that are not responding to other medication.


Dipyrone has a similar mechanism of action to acetaminophen and should not be used in conjunction with other painkillers that contain it, such as Panadol and Tylenol.


If Optalgin is being taken after consultation with a doctor, take it only as directed. Otherwise, the recommended dose for people over the age of 15 is one to two caplets up to 4 times per day, with a maximum of 8 on any single day. Pregnant women should not take more than six caplets on one day if they are past week 28.

If it is being taken in liquid form (Optalgin Drops), the recommended dosage for people over the age of 15 is 20-40 drops up to 3 times each day. The doses for children under the age of 15 are printed on the information leaflet that comes with the medications.

This text is for informational purposes only. Please consult with a doctor or pharmacist before using any medication. 

Optalgin does not produce adverse side effects in the majority of people who take it. When there are adverse effects, they may be experienced as nausea, vomiting, headache, weakness, fever or abdominal pain.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Optalgin can be taken to relieve moderate to severe pain, fever, and pain caused by muscle spasms.

  • What is another name for dipyrone?
    Dipyrone is marketed under a number of different names in various countries. It is incorrectly classified as a non-steroidal anti-inflammatory drug (NSAID). But instead, it is a non-opioid analgesic in the metamizole drug class.
  • What is the drug dipyrone used for?
    Optalgin is an antipyretic (fever reducing) and analgesic (pain relieving) drug. It has good gastrointestinal tolerability and also does not produce the effect of aspirin, which can cause excessive bleeding.
  • When was dipyrone banned in the US?
    Metamizole-class drugs were banned by the FDA in the 1970s after it was associated with the development of agranulocytosis, which is a life-threatening blood disorder. However, the incidence of this was low and it is still a matter of scientific research whether dipyrone should not be readmitted. It is still allowed in many countries, including France, Germany, Brazil, Hungary, Israel, Spain, Sweden, and Thailand.

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