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  • US Name:


  • Generic Names:

    Glucomin, Glucophage, Metformin, Glumetza

  • Active Ingredients:


  • Brand Manufacturer:


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Prescription Required

Metformin hydrochloride. It is used to help control blood sugar levels in people with type 2 or non-insulin dependent diabetes.

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Glumetza Extended Release Brand 1000mg
90 Tablets
Our price: $193.00
Metformin Generic 500mg
100 Tablets
Our price: $41.00
Glucophage Brand 1000mg
100 Tablets
Our price: $60.00
Glucomin Generic 850mg
30 Tablets
Our price: $16.00
Metformin Generic 850mg
30 Tablets
Our price: $16.00

*Please note all prices are in US dollars
Metformin is used as a first line treatment of type 2 diabetes in people who are overweight. It is used when diet and exercise have failed to control blood sugar levels. It can also be used in combination with other antidiabetic medicines to provide better control of blood sugar. Metformin in Israel is only available as a 850mg slow release tablet.
The more common side effects of metformin include:
  • heartburn.
  • stomach pain.
  • nausea or vomiting.
  • bloating.
  • gas.
  • diarrhea.
  • constipation.
  • weight loss.

Type 2 Diabetes Mellitus

Adjunctive therapy to diet and exercise to improve glycemic control in adults with type 2 diabetes

Monotherapy or with sulfonylurea

Immediate-release tablet or solution

  • Initial: 500 mg PO q12hr or 850 mg PO qDay with meals; increase dose in increments of 500 mg/week or 850 mg q2Weeks on the basis of glycemic control and tolerability
  • Maintenance: 1500-2550 mg/day PO divided q8-12hr with meal
  • Not to exceed 2550 mg/day

Extended-release tablet or suspension

  • 500 mg PO qDay with dinner; titrate by 500 mg/day qWeek; not to exceed 2000 mg/day

Type 2 Diabetes Prevention (Off-label)

850 mg PO qDay

Target dosing: 850 mg PO q12hr

  • What is metformin mainly used for?
    Metformin is mainly used to treat type 2 diabetes and gestational diabetes. Currently, metformin is the only recommended treatment for people at higher risk of developing diabetes.
  • How does Metformin work?
    Metformin works by increasing insulin sensitivity and decreasing the amount of glucose produced in the liver.
  • What happens if you take metformin without having diabetes?
    The off-label prescription of Metformin for non-diabetics comes from evidence that it can decrease inflammation. It has also been shown to protect against cardiovascular disease, cognitive impairment, to minimize cancer risk and progression, and so to prolong life.
  • How long can you stay on metformin?
    Treatment for type 2 diabetes with metformin is usually for life. If there are signs of kidney damage, doctors may switch to a different medicine. Do not stop taking metformin without talking to a doctor.
  • How quickly will you lose weight on metformin?
    Metformin can cause modest weight reductions when used regularly and for extended periods. In one trial, the average weight loss was between 4-7 pounds for each year of treatment. In another larger trial, it was found that metformin produced a roughly five pounds weight loss over the four-year period.
  • What is metformin used off-label for?
    Metformin also has several non-FDA-approved indications, including gestational diabetes, management of antipsychotic-induced weight gain, and the treatment and prevention of polycystic ovary syndrome (PCOS). Currently, metformin is the only ADA-recommended treatment for pre-diabetics.

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