The more common side effects of metformin include:
- stomach pain.
- nausea or vomiting.
- weight loss.
Type 2 Diabetes Mellitus
Adjunctive therapy to diet and exercise to improve glycemic control in adults with type 2 diabetes
Monotherapy or with sulfonylurea
Immediate-release tablet or solution
- Initial: 500 mg PO q12hr or 850 mg PO qDay with meals; increase dose in increments of 500 mg/week or 850 mg q2Weeks on the basis of glycemic control and tolerability
- Maintenance: 1500-2550 mg/day PO divided q8-12hr with meal
- Not to exceed 2550 mg/day
Extended-release tablet or suspension
- 500 mg PO qDay with dinner; titrate by 500 mg/day qWeek; not to exceed 2000 mg/day
Type 2 Diabetes Prevention (Off-label)
850 mg PO qDay
Target dosing: 850 mg PO q12hr