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  • US Name:


  • Israeli Names:


  • Active Ingredients:

    Lipase, Protease and Amylase

  • Brand Manufacturer:


  • Manufacturer Location:



Creon is used to treat deficient pancreatic enzyme secretions.
Creon 10,000 units does not require a Rx.
Creon 25,000 units is a prescription item.

BrandCreon 25 000 Units100 Capsules 99999 Abbott 1744
BrandCreon10,000 Units 100 Capsules8504 Solvay 1417

Creon® (lipase, protease, and amylase) is an combined enzyme replacement therapy for patients with deficient exocrine pancreatic secretions, cystic fibrosis, chronic pancreatitis, post-pancreatectomy, ductal obstructions caused by cancer of the pancreas, pancreatic insufficiency and for steatorrhea of malabsorption syndrome and post-gastrectomy (Billroth II and total).

Creon in Israel has a slightly different formulation than in the USA.  Below are the details with each enzyme so you can select the right product for you.

USP Units
Lipase Protease Amylase
Creon 12,000 USA 12000 38000 60000
Creon 10,000 Israel 10000 37500 33200
Creon 24,000 USA 24000 76000 120000
Creon 25,000 Israel 25000 62500 74700

Like all medicines, Creon can cause side effects (unwanted effects or reactions). But not everyone gets them. If you have severe or prolonged abdominal pain, contact your doctor immediately. Fibrosing colonopathy : A rare bowel disorder called fibrosing colonopathy was reported in a small number of children, with cystic fibrosis, taking large doses of both high and low-strength enzymes.

Creon is a high strength pancreatic enzyme supplement. Pancreatic enzyme supplements are used by people whose bodies do not make enough of their own enzymes to digest their food. How does it work? The enzymes in Creon work by digesting food as it passes through the gut. It is therefore essential that Creon is taken at the same time as eating a meal or a snack. This will allow the enzymes to mix thoroughly with the food.


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