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What Causes Irregular Periods (and What They Can Mean)

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picture of ovariesGrowing up in a family where I was the only girl, amongst a brood of older and younger brothers, I felt quite lost as I moved into puberty and on through my teenage years, because I was experiencing a problem that wasn’t shareable around the dinner table. Chatting behind closed doors with my Mom didn’t bring me a lot of cheer, because I was experiencing something that was quite strange to her, and she had no personal experience of the symptoms and could only suggest that I make an appointment to see a gynecologist to find out more.

The problem was that I had never experienced a regular pattern of monthly periods, and it was made worse because my circle of girl friends were almost all able to predict to within a couple of days at most when their monthly cycle would begin, and they could plan their activities ahead of time so that they never experienced embarrassing moments when unexpected changes started. In my case, there could be delays of days or even weeks, and too often monthly periods were skipped altogether.

Luckily, I was connected with a female gynecologist who was able to explain that irregular monthly cycles were far more common than most women thought, and that it wasn’t always a sign that something was “wrong”. She suggested a few simple things, starting with some blood screening tests and a full examination, but one of the most helpful suggestions was for me to keep a detailed diary, to take the guess-work out of diagnosing my condition. Not just start of bleeding, or other things directly related to the monthly cycle, but more subtle things like my general moods, energy levels, appetite swings, quality of sleep and even body temperature were all things that could pinpoint for her what may have been thrown off-balance in my body, resulting in irregular periods.

What is a normal monthly cycle

causes of irrregular periods

The idea of a single “normal” period schedule is misleading. A healthy monthly cycle can range from about 21 to 35 days. The often-quoted 28-day cycle is only an average, not a rule.

What matters more than exact timing is consistency. Someone who bleeds every 30 days with only small variations may be more regular than someone whose cycle shifts widely from month to month. When periods arrive unpredictably, skip months, or change dramatically in length, this pattern is often described as irregular periods.

Throughout the cycle, hormone levels rise and fall in a careful sequence. The hormones estrogen and progesterone help prepare the uterus for a possible pregnancy and then reset the system if pregnancy does not occur. When this balance is disrupted, timing and flow can change.

Cycle patterns also evolve across life stages:

  • Before puberty, periods have not yet begun
  • During puberty, cycles are often irregular as hormones settle
  • In reproductive years, cycles are usually more predictable
  • During perimenopause, hormone shifts often cause timing changes
  • Menopause marks the natural end of menstrual cycles

Common causes of irregular periods

Periods may lose their rhythm for many different reasons. These causes often overlap and may change over time.

Hormonal imbalances

Hormones act like messengers between the brain, ovaries, and uterus. When those signals fall out of sync, ovulation may not happen regularly.

  • Polycystic ovary syndrome (PCOS) can interfere with ovulation, leading to infrequent or missed periods
  • Thyroid disorders affect how the body uses energy and hormones overall
    • Hypothyroidism may cause heavier or less frequent bleeding
    • Hyperthyroidism may lead to lighter or more frequent periods
  • Changes in prolactin levels can suppress ovulation
  • Primary ovarian insufficiency occurs when ovarian function declines earlier than expected
  • All of these can disrupt overall hormonal balance

Life stage changes

Some irregularity is expected during natural transitions:

  • Puberty, when hormone signals are still maturing
  • Pregnancy, when periods stop completely
  • Breastfeeding, which can delay ovulation
  • Perimenopause, when hormone levels fluctuate before menopause

Lifestyle factors

The body responds quickly to physical and emotional stressors.

  • Emotional stress can disrupt brain–ovary signaling
  • Physical stress from illness or lack of sleep can delay ovulation
  • Sudden weight gain or weight loss may alter hormone production
  • Excessive exercise can suppress reproductive hormones

Reproductive organ conditions

Structural or inflammatory conditions can affect bleeding patterns.

  • Uterine fibroids may cause heavy or prolonged bleeding
  • Endometriosis can lead to pain and irregular flow
  • Polyps may cause spotting between periods
  • Pelvic inflammatory disease (PID) can disrupt normal uterine function

Medications

Some medications influence hormones or bleeding directly.

  • Starting or stopping hormonal birth control
  • Blood thinners that increase bleeding
  • Some antidepressants
  • Some antipsychotics that raise prolactin levels
  • Medications that affect ovulation or hormone signaling

Any concerns should be discussed with a qualified healthcare provider.

How gynecologists address monthly irregularity

When irregular cycles persist, gynecologists usually focus on identifying the underlying cause rather than treating symptoms alone.

  • Hormonal therapies may be used to create more predictable bleeding patterns
  • Thyroid medications may be considered when thyroid disorders are present
  • Insulin-sensitizing drugs are sometimes used in people with PCOS
  • Lifestyle adjustments may support hormone regulation
  • Surgical procedures may be considered for fibroids, polyps, or severe endometriosis
  • Existing medications may be reviewed or adjusted

Therapies

Since there are many possible different causes of irregular periods, doctors will tailor the therapy to match the most predominant ones.

  • PCOS: Metformin is an effective treatment for restoring regular menstrual cycles in women with Polycystic Ovary Syndrome, particularly those with insulin resistance. It works by reducing high insulin and androgen levels, which promotes ovulation. Results often appear within 3-6 months, with improvements in, or normalization of, menstrual cycles for many users. Metformin is not FDA-approved for the treatment of PCOS, but gynecologists routinely prescribed it off-label.
  • Uterine fibroids: While there are no cures for uterine fibroids, gonadotropin-releasing hormone (GnRH) agonists such as Lucrin and nonsteroidal anti-inflammatory drugs (NSAIDs) such as Nurofen can help manage the symptoms.
  • Fertility: Irregular periods can sometime cause problems when a woman is trying to fall pregnant, since timing of ovulation can be a key factor. One simple path to increasing fertility is by making sure that the body’s supply of vitamins is optimized, especially vitamins B and D.
  • PID treatment focuses on antibiotics to cure the infection, often a combination of injections and oral meds like Rocephin, Vibramycin, and Flagyl.
  • Hormone imbalances can be treated with oral medication, intra-uterine devices, vaginal creams and gels. The exact choice can only be made by a healthcare provider who is fully aware of all of the factors that have caused menstrual irregularity.

When to consult with a gynecologist

Medical evaluation is recommended when cycle changes are persistent or severe.

  • Periods missing for three months or longer
  • Bleeding between periods or after sex
  • Extremely heavy bleeding
  • Severe pelvic pain or cramping
  • Sudden or dramatic changes in cycle patterns

Takeaway Regular periods reflect overall body balance

Irregular periods are common and often manageable, but persistent changes deserve attention. Keeping a simple cycle diary can help identify patterns and support productive medical conversations.

Frequently asked questions about irregular periods

Can irregular periods happen even when someone feels healthy?

Yes. Many people with irregular periods feel otherwise well. Hormone fluctuations can occur quietly, without obvious symptoms. Stress, travel, weight changes, or early life-stage transitions can all affect timing without causing illness. However, ongoing irregularity can still provide useful information about how the body is functioning. That is why tracking patterns over time and discussing them with a healthcare provider can be helpful, even when no other symptoms are present.

Is a perfect schedule necessary for a healthy cycle?

No. A perfect schedule is not required for good reproductive health. Cycles naturally vary by a few days. What matters more is whether the pattern is generally predictable for that individual. Large swings in timing, skipped months, or sudden changes may signal hormone shifts or life-stage transitions. A healthcare provider can help determine whether variation is within a healthy range or worth investigating further.

How does PCOS affect the monthly cycle?

PCOS affects how the ovaries release eggs. When ovulation does not happen regularly, periods may be infrequent or absent. Hormone levels, including androgens, may also be higher than usual. PCOS presents differently in each person, which is why diagnosis usually involves symptom review, hormone testing, and sometimes imaging. Understanding the condition helps explain why cycles may not follow a predictable pattern.

Why do thyroid disorders change period timing?

The thyroid helps regulate metabolism and hormone use throughout the body. In Hypothyroidism, slower metabolism may lead to heavier or less frequent periods. In Hyperthyroidism, faster metabolism can shorten cycles or reduce bleeding. Because thyroid hormones interact closely with reproductive hormones, even mild thyroid imbalances can affect menstrual timing.

Are irregular periods common during perimenopause?

Yes. Perimenopause is known for unpredictable cycles. Hormone levels rise and fall unevenly, which can lead to missed periods, shorter cycles, or heavier bleeding. These changes are part of a natural transition, but unusually heavy bleeding or severe pain should still be evaluated to rule out other conditions.

When should irregular periods not be ignored?

Irregular periods should be evaluated when they persist, worsen, or are accompanied by pain, heavy bleeding, or bleeding between cycles. Sudden changes can signal hormone shifts or structural conditions that benefit from early attention. Even when causes are benign, understanding what is happening can provide reassurance and help guide future health decisions.

Picture of Linda Aarons

Linda Aarons

Linda is a seasoned health writer, parent, and grandparent who divides her time between the U.S. and Israel. Passionate about travel and wellness, she brings valuable insights and a personal perspective to her writing.
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