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Verquvo Brand 10mg
28 Tablets
Our price: $179.00
Verquvo Brand 5mg
14 Tablets
Our price: $98.00
Verquvo Brand 2.5mg
14 Tablets
Our price: $98.00

*Please note all prices are in US dollars
Verquvo (generic name: vericiguat) is an oral medication prescribed for adults with chronic heart failure symptoms classified as HFrEF (ejection fraction less than 45%.) Vericiguat is a novel drug that acts as a soluble guanylate cyclase (sGC) stimulator. It increases cyclic guanosine monophosphate (cGMP) levels, leading to vasodilation and improved cardiac function. It is used primarily to reduce the risk of severe cardiovascular events leading to hospitalization for heart failure. Heart failure is when the heart is weak and cannot pump enough blood to the body. Patients with HFrEF can exhibit symptoms like shortness of breath, fatigue, reduced capacity to exercise, fluid retention (edema), and accelerated heartbeat.


Verquvo comes in three strengths. The prescribing doctor will determine the dose and how it should be taken. The recommended starting dose is one tablet of 2.5 mg daily. The doctor will adjust the dose depending on how well it is tolerated during treatment. The dose will usually be increased after two weeks to one tablet of 5 mg daily and after two weeks up to the maximum of one tablet of 10 mg daily. If symptoms of low blood pressure are felt while taking Verquvo, this can cause dizziness and light-headedness, in which case the doctor may temporarily reduce the dose or halt treatment with Verquvo. Take one tablet at the same time each day with food. If you cannot swallow the tablet, you may crush it and mix it with water. Take this mixture immediately after preparing it. Do not exceed the recommended dose.  

This is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

Patients taking Verquvo have experienced symptoms coming from low blood pressure (hypotension), such as blurry vision, confusion, dizziness, syncope (fainting), lightheadedness, nausea or vomiting, or sleepiness.

Some other less common side effects include anemia (reduced number of red blood cells), indigestion (dyspepsia), or heartburn (gastro-oesophageal reflux).

If these persist or worsen, consult with a doctor or pharmacist.

Heart failure develops because the muscles in the heart become weak or stiff, reducing the ability to pump blood through the blood vessels normally. Congestive heart failure develops from the accumulation of blood and fluid in the lungs, and the body doesn’t get enough oxygen-rich blood to work properly.

Heart failure is most often caused by other heart conditions, including

  • Atherosclerosis (coronary artery disease or CAD)
  • Heart attack
  • High blood pressure
  • Arrhythmia (where the heart rhythm is irregular)
  • Heart valve problems

Doctors diagnose heart failure by measuring the percentage of blood the heart can pump with each beat, measured by a unit called ejection fraction, or EF. This measures how strongly the left ventricle squeezes blood out of the heart. For a healthy heart, the EF reading is between 55% and 75%. If the EF measure is below 40%, it indicates that the ventricle isn’t ejecting enough blood to the body, and this is heart failure with a reduced ejection fraction (HFrEF).

Patients with HFrEF typically exhibit symptoms such as shortness of breath, fatigue, reduced exercise tolerance, edema (fluid retention), and rapid heartbeat.

Medications and lifestyle modifications such as dietary changes, exercise, and fluid management may be crucial in managing HFpEF.

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