What medication is used for VMS in menopause?

Vezoah is an FDA-approved non-hormone treatment for moderate-to-severe VMS. Trials of fezolinetant have shown that it can lead to reductions in VMS frequency and severity, as well as improvement in sleep patterns without negative side effects such as weight gain or decreased libido.

Is neurokinin 3 receptor antagonist for hot flashes?

While hormone replacement therapy (HRT) is an effective treatment for hot flashes, it carries risks and side effects that limit its suitability in many cases for women in menopause. NK3 receptor antagonists are a novel therapeutic path that leads to effective non-hormonal treatment for menopausal hot flashes.

What causes night sweats and hot flushes?

Hot flashes or flushes (HFs) and night sweats are menopausal symptoms that occur due to changes in gonadal hormones. They are known as vasomotor symptoms (VMS), commonly occurring with the onset of menopause. VMS are a form of temperature dysfunction.

What hormones change during menopause?

As a woman matures, the supply of eggs in the ovaries start to diminish and monthly ovulation becomes irregular. Estrogen and progesterone production falls off, and this decrease causes most of the symptoms of menopause.

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Home / Online Pharmacy / Veozah

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US Name:

Veozah
Alternative Names:

Veozah
Active Ingredients:

Fezolinetant
Brand Manufacturer:

Astellas
Manufacturer Location:
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Veozah ^*

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Veozah is a non-hormone treatment for moderate to severe vasomotor symptoms of menopause.

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Description
Side Effects
Indications
FAQ
Video

Veozah (fezolinetant) is a hormone-free treatment of moderate to severe vasomotor symptoms (VMS) due to menopause. The symptoms of VMS include hot flashes and night sweats.

Before the approval of Vezoah, the standard treatment for VMS has been hormone replacement therapy (HRT) using estrogen supplements. However, this path can negatively affect the heart and increases the risk of breast cancer. The FDA has now approved fezolinetant, a neurokinin receptor 3 antagonist (NK3), as a nonhormonal treatment for VMS.

Dosage

Take Vezoah as prescribed and follow the instructions supplied by the pharmacist. The usual oral dose is a single tablet taken at about the same time each day. Vezoah can be taken with or without food.

If a dose is forgotten, take the missed dose as soon as remembered on the same day. If there is less than 12 hours before the next scheduled dose, do not take the missed dose and continue with the regular schedule the following day. Do not double-dose to make up for the missed dose. If several doses are missed, consult a doctor for advice.

Storage

Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of that month. Read our helpful blog for tips on handling medicine safely.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.

Read the manufacturer’s information leaflet that comes with the medication.

The most commonly reported side effects of Vezoah are:

Diarrhea
Insomnia
Abdominal pain

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Veozah is the first FDA-approved non-hormonal treatment for the symptoms of menopause, including hot flashes and night sweats.

Menopause sees the body going through major hormonal changes. During perimenopause, there is a steady decrease in the amount of hormones produced in the ovaries, mainly estrogen and progesterone. Monthly periods become erratic and finally stop altogether. 12 months after the last period, a woman is in menopause.

When the ovaries no longer make enough estrogen and progesterone, it can result in the symptoms of hormone deficiency, which include vasomotor symptoms like hot flashes and night sweats. Other symptoms include headaches and migraines that are worse than usual, muscle aches and joint pains, changes in body shape, weight gain, skin changes including dry and itchy skin, vaginal dryness, pain, itching or discomfort during sex, and reduced libido (sex drive).

Vezoah is an FDA-approved non-hormone treatment for moderate-to-severe VMS. Trials of fezolinetant have shown that it can lead to reductions in VMS frequency and severity, as well as improvement in sleep patterns without negative side effects such as weight gain or decreased libido.

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