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Veltassa is used to treat adults with high potassium levels in their blood.

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30 sachets
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Veltassa (generic name: patiromer) is prescribed to treat adults with hyperphosphatemia (high levels of potassium in the blood). Veltassa binds to potassium in the gut before it can be absorbed and prevents the potassium from reaching the bloodstream. 


Veltassa is a powder in single-dose sachets containing 8.4 mg of patiromer sorbitex calcium. Follow the instructions from the prescribing healthcare provider and guidelines printed on the patient instruction leaflet included in the package.

If one dose is missed, take it as soon as possible on the same day. Do not double-dose the following day to compensate for the missed dose. If more than one dose has been missed in succession, contact a doctor immediately.

Caution: Valpressa contains sorbitol. If you are sensitive to this substance, make sure that the prescribing doctor or pharmacist is aware before starting treatment.

Veltassa may cause side effects in some users. They should be transient, but if they persist or worsen, a doctor should be consulted. The observed side effects include:

  • Constipation
  • Diarrhea
  • Abdominal pain
  • Flatulence


Low levels of magnesium may be measured in blood tests.

Hyperphosphatemia can have several possible common causes, including:

  • Advanced chronic kidney disease.
  • Hypoparathyroidism.
  • Lower-than-normal blood pH caused by respiratory or metabolic acidosis.


Rarely, hyperphosphatemia can also develop due to systemic problems, such as diabetes-related ketoacidosis, muscle damage (rhabdomyolysis), pseudohypoparathyroidism, sepsis, or a crush injury.

Excess dietary phosphates or receiving too much phosphate in an enema can be an external cause.

Blood tests may show elevated levels of potassium (hyperphosphatemia). The normal level is 4.5 milligrams per deciliter (mg/dL). Patients with hyperphosphatemia are in danger of weakness, cardiac problems, or paralysis. Elevated potassium levels in the blood can affect how nerves control the muscles.

High potassium levels can result in several heart conditions, such as abnormal heart rhythm, vascular calcification, and arteriosclerosis, producing systolic hypertension, and widened pulse pressure, which can cause left ventricular hypertrophy.

  • What is the mechanism of Veltassa?

    Veltassa (patiromer) increases fecal excretion of potassium through the binding of potassium in the lumen of the gastrointestinal tract. The binding of potassium reduces the concentration of free potassium in the gastrointestinal lumen, reducing blood potassium levels.
  • What is the indication of high potassium (hyperphosphatemia)?

    A routine blood test that shows a phosphate level greater than 4.5 milligrams per deciliter (mg/dL) indicates hyperphosphatemia. Doctors will routinely order additional tests to check for systemic conditions.
  • Can I take Veltassa every other day?

    Take Veltassa only as prescribed by the doctor. If Veltassa is stopped, even for a few days, potassium levels can increase rapidly.
  • What foods to choose if I have high potassium?

    Avoid dried beans, black-eyed peas, yams, cooked greens, spinach, and sweet potato pie, which are all high in potassium. The best low-potassium foods that help regulate potassium levels include fruits such as apples, most berries, cherries, grapes or grape juice, and cranberries or cranberry juice. Eggs are considered a low-potassium food (one large egg contains about 63 mg of potassium) but check with a doctor or dietitian to find out if there are other issues.
  • Can you eat after taking Veltassa?

    Patiromer is meant to be taken once per day with or without food. The powder must be mixed with water and stirred well. Drink all of it right away.


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