Taltz (generic name: ixekizumab) is a prescription medication used to treat several inflammatory conditions:
- Moderate to severe cases of plaque psoriasis in adults and children aged 6 years and older.
- Active cases of psoriatic arthritis in adults.
- Active cases of ankylosin spondylitis in adults.
- Active cases of non-radiographic axial spondyloarthritis in adults with objective signs of inflammation.
Ixekizumab is a monoclonal antibody that targets interleukin-17A (IL-17A), a protein involved in inflammatory processes. By inhibiting IL-17A, Taltz helps reduce inflammation and alleviate symptoms associated with these conditions.
For more information, refer to the page on Taltz from the
Americal College of Rheumatology.
Dosage
Taltz is administered via subcutaneous injection. Patients should follow their healthcare provider’s instructions on proper injection techniques and must take care to adhere to the dosing schedule. The usual prescribed doses are:
- For plaque psoriasis (adults): An initial dose of 160 mg (two 80 mg injections) followed by 80 mg every two weeks for 12 weeks, then 80 mg every four weeks.
- For plaque psoriasis (children ≥6 years): Dosing is based on body weight.
- For psoriatic arthritis: An initial dose of 160 mg, then 80 mg every four weeks.
- For ankylosing spondylitis and non-radiographic axial spondyloarthritis: An initial dose of 160 mg, then 80 mg every four weeks.
If a dose is missed, it should be taken as soon as possible, and subsequent doses should be spaced as originally scheduled.
Storage
Store Taltz in the refrigerator at 2°-8°C (36°-46°F) in its original carton to protect from light. Do not freeze. If necessary, Taltz can be stored at room temperature up to 30°C (86°F) for a maximum of 5 days. Once stored at room temperature, do not return it to the refrigerator. Keep out of reach of children. For more information, read our article on drug storage.
Common Questions About Taltz
Can I self-inject Taltz at home?
Yes, after proper training from your healthcare provider, you can self-inject Taltz at home.
Can Taltz be used for other conditions besides psoriasis and arthritis?
Taltz is primarily approved for specific inflammatory conditions. Use for other conditions should be discussed with your healthcare provider.
What are monoclonal antibodies?
Monoclonal antibodies are lab-made proteins that can bind to specific targets in the body, such as IL-17A, to modulate immune responses.
This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.
Read the information leaflet that comes with the medication.
Most people who use Taltz do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.
Some of the side effects that have been reported include injection site reactions (such as redness or pain), upper respiratory tract infections, nausea, and fungal infections. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, swelling, or severe abdominal pain.
Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.
The main uses of are for the treatment of:
- Plaque psoriasis, which is a chronic autoimmune condition characterized by red, scaly skin patches.
- Psoriatic arthritis, an inflammatory arthritis associated with psoriasis, causes joint pain and swelling.
- Ankylosing spondylitis, an inflammatory disease affecting the spine, leading to pain and stiffness.
- Non-radiographic axial spondyloarthritis, a form of spondyloarthritis without visible radiographic damage but with clear signs of inflammation.