What is Tagrisso?
Tagrisso is a prescription oral medication used to treat specific types of non-small-cell lung cancer (NSCLC). This medicine is a form of targeted therapy known as a kinase inhibitor. It is designed for lung cancers that have abnormal epidermal growth factor receptor (EGFR) genes. Tagrisso precisely targets the cancer cells with these mutations. This action helps to slow or stop the growth of the tumor. It is a third-generation EGFR inhibitor, often effective when others are not.
How does Tagrisso work?
Tagrisso works by specifically targeting and blocking mutated EGFR proteins found in certain cancer cells. In some lung cancers, a mutated EGFR gene is always active. This sends constant signals for cells to grow and divide uncontrollably. Tagrisso attaches to this specific mutated protein. It effectively turns off the signal that promotes cancer cell growth. This targeted action avoids harming healthy cells as much as traditional chemotherapy might. It helps manage the cancer’s progression with high precision.
Who is Tagrisso for?
Tagrisso is for adults diagnosed with non-small-cell lung cancer that has spread to other parts of the body. A doctor must first confirm the presence of specific EGFR mutations through a genetic test. It can be prescribed as a first-line treatment for patients with certain EGFR mutations. It is also used for patients whose cancer has progressed after treatment with other EGFR-targeting drugs. This medication is suitable for those whose tumors have developed a specific T790M resistance mutation.
Dosage and administration
Tagrisso is typically taken as an 80 mg tablet once each day. Your doctor will determine the correct dose for your specific situation. You can take the tablet with or without a meal. It is important to swallow the tablet whole with a glass of water. Do not crush or chew it. If you have trouble swallowing, the tablet can be dissolved in water. Always follow your healthcare provider’s instructions carefully for the best results. Treatment often continues as long as the medication is effective or until side effects become unmanageable.
Side effects
Tagrisso may cause side effects, but not everyone will experience them. It is important to discuss potential risks with your doctor. Some patients may experience mild to moderate side effects.
- Diarrhea
- Skin rash and dryness
- Nail problems, including infection or tenderness
- Mouth sores (stomatitis)
- Low blood cell counts (platelets, white cells)
In rare cases, Tagrisso can cause more severe problems. A serious lung condition called interstitial lung disease (ILD) is a risk. Symptoms of ILD include new or worsening cough, fever, and trouble breathing. Heart problems and eye issues can also occur. Contact your doctor immediately if you experience any of these serious symptoms.
Why buy from IsraelPharm?
IsraelPharm offers a trustworthy and cost-effective way to get your prescribed Tagrisso medication. We understand the high cost of cancer treatment. We are committed to making it more affordable. You can save significantly compared to average U.S. retail prices. We ensure you receive genuine, brand-name medication directly from the manufacturer. Our streamlined ordering process and international delivery provide a simple and secure way to access your vital treatment from home. Our customer service team is ready to assist you with any questions.
Tagrisso can cause side effects ranging from mild to severe. You should review the full patient information leaflet included with your medicine. Contact your doctor if you experience concerning symptoms.
Common Side Effects
- Diarrhea
- Rash, dry skin, or acne
- Pain, redness, or infection around fingernails or toenails
- Mouth sores
- Fatigue
- Changes in blood counts (low platelets or white blood cells)
Serious Side Effects
- Lung Problems: A severe condition called interstitial lung disease (ILD) with symptoms like shortness of breath, cough, and fever.
- Heart Conditions: Irregular heartbeats (QTc prolongation) and heart failure.
- Eye Problems: Inflammation of the cornea (keratitis).
- Skin Reactions: Severe skin rashes, including Stevens-Johnson syndrome.
Tagrisso (osimertinib) is a targeted therapy used to treat certain types of non-small-cell lung cancer (NSCLC). Its use is specific to cancers with particular genetic characteristics.
- First-Line Treatment: For patients with metastatic NSCLC whose tumors have specific epidermal growth factor receptor (EGFR) gene mutations (exon 19 deletions or exon 21 L858R mutations).
- Second-Line Treatment: For patients with metastatic NSCLC whose disease has progressed on or after previous EGFR tyrosine kinase inhibitor (TKI) therapy and whose tumors have the T790M mutation.
- Adjuvant Therapy: To treat patients with early-stage EGFR-mutated NSCLC after the tumor has been surgically removed.