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Steglatro is an oral medication for treating Type 2 Diabetes.

Prescription Required
28 Tablets
28 Tablets
*Please note all prices are in US dollars

Steglatro (generic name: ertugliflozin) is a sodium-glucose cotransporter 2 (SGLT2) inhibitor.

Ertugliflozin acts as a blocker for the SGLT2 protein in the kidney tubules, whose primary function is to reabsorb the glucose from the filtered liquid back into the body. By doing this, the drug ensures that glucose is expelled through urine instead and not taken back into the bloodstream.

As well as this effect on glucose, Steglatro also affects the handling of salt in the kidneys. The effects of this include reducing the heart’s workload and decreasing the internal pressure inside the kidney’s filtering units.

The benefits include:

  • An improvement in glycemic control for adults with type 2 diabetes
  • A reduction in the risk of sustained kidney damage from high salt excretion
  • A reduction in the risks of heart failure for adult patients suffering from kidney failure


The prescribing doctor sets the dosage based on each patient’s underlying condition. It is essential to follow the prescribing doctor’s instructions. Read the Patient Information leaflet that comes with the package.

Some side effects have been reported:

  • Vaginal yeast infections in women can develop a vaginal odor, white or yellowish vaginal discharge, or vaginal itching.
  • Yeast infection of the skin around the penis (balanitis)
  • Nasopharyngitis
  • Urinary tract infections.

If these fail to clear up after a few days or worsen, consult with a physician or pharmacist.

Please read the manufacturer’s Patient Leaflet that comes with the medication. Not all side effects are listed here. Consult a healthcare provider if you experience these or other unexpected effects.

Steglatro can be prescribed for:

  • glycemic control in adults with type 2 diabetes mellitus, as an adjunct to diet and exercise
  • reducing the risk of kidney function decline and end-stage kidney disease
  • reducing risks of heart failure in adults with chronic kidney disease or type 2 diabetes
  • Can ertugliflozin be taken with metformin?

    Combining ertugliflozin and metformin, along with proper diet and exercise, is used to treat high blood sugar levels caused by type 2 diabetes in patients who do not have control of their blood sugar on ertugliflozin or metformin alone.
  • What class of drug is ertugliflozin?

    Steglatro is a sodium-glucose co-transporter 2 inhibitor (SGLT2i), which lowers blood sugar levels by causing the kidneys to excrete more glucose in the urine. Together with diet and exercise, Steglatro is prescribed to lower blood sugar in adults with type 2 diabetes. It can also be prescribed off-label to prevent heart failure.
  • Does ertugliflozin affect weight?

    Metformin and Steglatro prescribed together are associated with mild and sustained weight loss in patients with type 2 diabetes.
  • Why is SGLT2 contraindicated in patients with renal failure?

    Because SGLT2 inhibitors can cause blood volume contraction, inhibitors such as Steglatro can cause acute kidney injury (AKI). Physicians will consider factors that might increase the risk of acute kidney injury, including hypovolemia, chronic renal insufficiency, and chronic heart failure, before prescribing Steglatro.
  • Can you drink alcohol while taking ertugliflozin?

    Patients with type 2 diabetes taking Steglatro are usually advised to limit their alcohol intake. Alcohol can cause either hypoglycemia or hyperglycemia in patients with diabetes, depending on the timing and quantity. Hypoglycemia (low sugar) can occur if the consumption of alcohol coincides with taking the medication.


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