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  • US Name:

    Saphris

  • Israeli Names:

    Saphris

  • Active Ingredients:

    Asenapine as Maleate

  • Brand Manufacturer:

    Lundbeck

  • Manufacturer Location:

    Ireland

Saphris

Indicated in the treatment of schizophrenia and bipolar disorder

This product is not currently available

Schizophrenia

SAPHRIS is indicated for the treatment of schizophrenia in adults. The efficacy of SAPHRIS was established in two 6-week trials and one maintenance trial in adults Bipolar Disorder Monotherapy: SAPHRIS is indicated for the acute treatment of manic or mixed episodes associated with bipolar I disorder. Efficacy was established in two 3-week monotherapy trials in adults Adjunctive Therapy: SAPHRIS is indicated as adjunctive therapy with either lithium or valproate for the acute treatment of manic or mixed episodes associated with bipolar I disorder. Efficacy was established in one 3-week adjunctive trial in adults.

Saphris (asenapine) is an atypical antipsychotic psychiatric medication used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder). Common side effects of Saphris include:

  • drowsiness,
  • dizziness,
  • numbness or tingling of the mouth,
  • restlessness,
  • constipation,
  • dry mouth,
  • sleep problems (insomnia),
  • upset stomach, and
  • weight gain.

Saphris may cause muscle/nervous system problems (extrapyramidal symptoms-EPS). Tell your doctor if you notice the following side effects of Saphris including:

  • feelings of anxiety/agitation/jitteriness,
  • drooling or trouble swallowing,
  • constant need to move,
  • shaking (tremor),
  • shuffling walk,
  • stiff muscles,
  • severe muscle spasms or cramping (such as twisting neck, arching back, eyes rolling up), and
  • mask-like expression of the face.

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