Schizophrenia
SAPHRIS is indicated for the treatment of schizophrenia in adults. The efficacy of SAPHRIS was established in two 6-week trials and one maintenance trial in adults Bipolar Disorder Monotherapy: SAPHRIS is indicated for the acute treatment of manic or mixed episodes associated with bipolar I disorder. Efficacy was established in two 3-week monotherapy trials in adults Adjunctive Therapy: SAPHRIS is indicated as adjunctive therapy with either lithium or valproate for the acute treatment of manic or mixed episodes associated with bipolar I disorder. Efficacy was established in one 3-week adjunctive trial in adults.
Saphris (asenapine) is an atypical antipsychotic psychiatric medication used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder). Common side effects of Saphris include:
- drowsiness,
- dizziness,
- numbness or tingling of the mouth,
- restlessness,
- constipation,
- dry mouth,
- sleep problems (insomnia),
- upset stomach, and
- weight gain.
Saphris may cause muscle/nervous system problems (extrapyramidal symptoms-EPS). Tell your doctor if you notice the following side effects of Saphris including:
- feelings of anxiety/agitation/jitteriness,
- drooling or trouble swallowing,
- constant need to move,
- shaking (tremor),
- shuffling walk,
- stiff muscles,
- severe muscle spasms or cramping (such as twisting neck, arching back, eyes rolling up), and
- mask-like expression of the face.