Remeron, Zisprin ^*

This text is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

The most common side effects of  Remeron include:

• increased appetite and weight gain
• sleep disorders like sleepiness, drowsiness, fatigue, vivid dreams,
• headaches
• dry mouth
• tremors
• instability
• stomach upsets (diarrhea, constipation, abdominal pain)
• skin rash
• arthritis
• back pain
• dizziness
• hypotension while standing
• swelling in the feet and ankles.

If these persist or worsen, consult with a doctor or pharmacist.

There are some rare but serious side effects that require immediate medical attention.

• Hypersensitivity: rash, itching, redness, swelling of the skin, possibly accompanied by fever; swelling of the face, eyelids, lips, tongue, and throat; shortness of breath; feeling of suffocation in the throat.
• Stevens-Johnson syndrome or TENS syndrome: rash, blisters on the skin or mouth, red and irritated eyes, itchy or peeling skin.
• Serotonin syndrome: diarrhea, abdominal pain, nausea, restlessness, nervousness, irritability, rapid heartbeat, muscle pain, tremors, high fever, increased sweating.
• Hyponatremia (low levels of sodium in the blood): headaches, difficulty concentrating, forgetfulness, confusion, difficulty maintaining balance.
• Inflammation of the liver: weakness, fatigue, lack of appetite, nausea and vomiting, severe abdominal pain, dark urine, and jaundice in the skin or the white part of the eyes.
• Mania: elation, feeling of superiority, fast and loud talking, restlessness, hyperactivity.
• Aggravation of the state of depression, especially with suicidal thoughts (thoughts of death and self-harm), changes in behavior, worsening of depression, withdrawal, aggressive behavior, and inability to control anger.
• Immune system suppression: high fever, sore throat, appearance of ulcers in the oral cavity,  pain in the mouth, convulsions, rapid heartbeat, fainting, dizziness.

Remeron is FDA-approved for the treatment of unipolar major depressive disorder (MDD).

Depression can arise from an imbalance of brain chemicals along with contributing factors. It often runs in families. It can be triggered by life events or certain health conditions. Sometimes, depression can emerge without a cause.

What are the signs of depression?

While symptoms may vary from person to person, the main indicators of depression are;

• Persistent feelings of sadness, anxiety or emptiness
• Loss of interest in most activities
• Changes in appetite and weight
• Shifts in sleep patterns, such as insomnia or excessive sleeping
• Slowed physical movements or speech and thinking
• Restlessness 
• Increased irritability and agitation
• Decreased energy levels and feeling consistently fatigued or sluggish
• Continual feelings of worthlessness or excessive guilt
• Difficulty focusing or making decisions
• Recurring thoughts about death or suicide, or suicide attempts (Note: Immediate intervention is necessary)

If you experience five or more of these symptoms for two weeks, you may receive a diagnosis of depression. 

Off-label Clinical Uses

• Insomnia
• Panic disorder
• Prophylaxis of chronic tension-type headache
• Social anxiety disorder
• Post-traumatic Stress Disorder(in combination with SSRI)
• Fibromyalgia