What is Relistor?
Relistor is a brand-name prescription medication containing the active ingredient methylnaltrexone bromide. It is designed specifically to treat a type of constipation called opioid-induced constipation (OIC) in adults. This condition is a common side effect of taking opioid medications for chronic pain. Relistor is administered as an injection just under the skin (subcutaneously). It provides relief by targeting the underlying cause of OIC without impacting the pain-relieving effects of the opioid.
How does Relistor work?
Relistor works as a peripherally acting mu-opioid receptor antagonist. Opioid pain medications bind to receptors throughout the body, including in the gut. This binding slows down bowel movements, leading to hard, dry stools that are difficult to pass. Relistor selectively blocks these opioid receptors in the gastrointestinal tract. However, it does not cross the blood-brain barrier. This means it can reverse constipation without interfering with the pain relief provided by the opioid medication in the central nervous system.
Who is Relistor for?
Relistor is for adults who are experiencing constipation caused by long-term use of opioid medications for chronic non-cancer pain. It is a suitable treatment option when standard laxative treatments have not provided adequate relief. This medication is intended for patients who need to continue their opioid therapy for pain management but suffer from its gastrointestinal side effects. A doctor will determine if Relistor is the right choice based on a patient’s medical history and current condition. It is not intended for other types of constipation.
Dosage and administration
Relistor dosage and administration should be followed exactly as prescribed by your healthcare provider. The typical dose is an injection given under the skin of the thigh, abdomen, or upper arm. Patients are often started on a 12 mg dose administered as needed, but at least once daily. After an injection, a bowel movement can occur quickly, sometimes within 30 minutes to a few hours. For this reason, it is recommended to be near a toilet after administering the dose. Relistor comes in pre-filled syringes for ease of use. Always follow the instructions provided with the medication for proper injection technique.
Side effects
Relistor may cause certain unwanted side effects, though not everyone will experience them. The most common side effects are related to the digestive system as the medication begins to work. You should discuss potential side effects with your doctor before starting treatment.
- Abdominal pain or cramping
- Nausea
- Diarrhea
- Excessive sweating (hyperhidrosis)
- Hot flushes
- Tremors or shivering
- Chills
In rare cases, more serious side effects can occur. These include symptoms of opioid withdrawal or a tear in the stomach or intestinal wall (gastrointestinal perforation). Contact your doctor immediately if you experience severe stomach pain that does not go away, anxiety, or persistent diarrhea.
Why buy from IsraelPharm?
IsraelPharm offers a reliable and cost-effective way to get the medications you need. We are a licensed pharmacy providing authentic, brand-name drugs like Relistor sourced from regulated international distributors. Our streamlined online platform allows you to order your prescription with ease from the comfort of your home. We pride ourselves on excellent customer service, ensuring your privacy and providing support throughout the ordering process. By removing intermediaries, we offer significant savings on your essential medications without compromising on quality or safety.
Most individuals using Relistor experience minimal side effects. However, some common reactions may occur, including:
- Stomach pain, nausea, or diarrhea
- Hot flashes or flushing
- Tremors and chills
- Increased sweating
Consult your doctor if these symptoms persist or worsen. Seek immediate medical attention for severe, worsening abdominal pain, as this could signal a rare but serious condition. This is not a complete list of all possible side effects.
Relistor is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic, non-cancer related pain. This specific type of constipation occurs when opioid painkillers slow down the normal movement of the intestines, making stools hard and difficult to pass. It is used when conventional laxative therapies have not been effective.