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    Estradiol / Norgestrel

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Progyluton is a form of hormone replacement therapy that supplements estrogen levels for women entering or already in menopause.

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Progyluton Brand 2mg / 0.5mg
21 Tablets
Our price: $15.00

*Please note all prices are in US dollars
Progyluton (estradiol) is a hormonal replacement therapy (HRT) that treats irregularities in the menstrual cycle and pre-menstrual disturbance. It is not a contraceptive.
Progyluton acts as an estrogen supplement that boosts the levels of this sex hormone that declines as women age and pass from pre-menopause into full menopause. Lower estrogen levels can also be caused by ovarian disorders, pituitary gland misfunction, or from surgical removal of the ovaries (hysterectomy or oophorectomy). Along with estrogen, Progyluton supplied small quantities of progesterone, which are required to lower the risk of ovarian cancer that accompanies estrogen supplements.


The dose and regimen is set by the prescribing doctor. The usual dose is one tablet each day for 21 days, in the sequence of days-of-the week as determined by the first day on which the dosage is started. . The tablets are color-coded so that white tablets are taken on days 1-11, followed by brown tablets for the next 11 days. After 21 days, there is a 7 days rest. It is also important to set a timetable and adhere to the set time.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication. 

Read the information leaflet that comes with the medication. It contains important information relating to the dosage and how the tablets should be taken.

Most people who use Progyluton do not experience any negative side effects. Doctors prescribe Progynova because they assess that the benefits that such treatment yields outweighs any likely unwanted effects.

Some of the side effects that have been reported include:

  • Bleeding irregularities and spotting.
  • Mood changes.
  • Breast tenderness, slight bloating or fluid retention.
  • Nausea and vomiting.
  • Headache.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Falls in estrogen levels can come as a direct outcome of aging (pre-menopause followed by menopause) or as a result of ovarian conditions, thyroid deficiencies, and surgical removal of the ovaries. The main symptoms of low estrogen are hot flashes, night sweats, bloating, vaginal changes, hair thinning, and mood changes. The early signs of premenopause are irregular periods and spotting.

Menopause typically begins around the ages of 45 to 50, but it can also occur earlier, possibly due to conditions like premature ovarian insufficiency. Anyone who notices symptoms of menopause before the age of 45 is advised to consult a healthcare professional for a proper diagnosis and explore available treatment choices.

Important Information Regarding Hormone Replacement Therapy (HRT):

HRT medications are powerful tools for managing hormonal changes. To ensure the medication’s safety and effectiveness, it’s important to understand who can benefit from it most. According to the Israeli Ministry of Health regulations, Progyluton is currently only prescribed for individuals assigned female at birth.

  • Can you replace estrogen during menopause?
    Progyluton is a form of hormone replacement therapy (HRT) that is most often used to treat menopausal symptoms, which can include hot flashes, mood changes and vaginal discomfort. Hormone replacement therapy contains the female hormone estrogen, together with progesterone, which offsets the risk of ovarian cancer that estrogen on its own carries.
  • What are the signs of low estrogen?
    The common signs of low estrogen include dry skin, tender breasts, trouble concentrating, mood changes, irritability, vaginal dryness or atrophy, hot flashes, night sweats. During pre-menopause, the main symptoms are irregular periods.
  • Is it too late to take estrogen after menopause?
    Hormone therapy can prevent changes to bone health in women aged up to 60 years. Some women may be advised to continue HRT after that age, considering their general health and bone density or in case of a history of fracture.
  • Do people who take HRT look younger?
    Progyluton boosts estrogen levels back to where they were before menopause set in. It can slow down changes in the skin that come as a result of aging, by improving skin elasticity and thickness, along with raising collagen and water content. These improve the appearance of the skin.

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