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Pristiq is used for symptomatic relief in patients with major depressive disorder

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Pristiq Brand 50mg
30 Tablets
Our price: $120.00
Pristiq Brand 100mg
30 Tablets
Our price: $120.00

*Please note all prices are in US dollars
Pristiq is an antidepressant medication that contains the active ingredient desvenlafaxine succinate. Desvenlafaxine succinate works by increasing levels of norepinephrine and serotonin in the brain, and is part of the drug group called ‘serotonin and norepinephrine reuptake inhibitors’ (SNRIs).  Pristiq is a medication used to treat major depressive disorder in adults as a symptomatic reliever and is usually not used as a long-term treatment. For dosing and duration of treatment, consult with a doctor or healthcare provider. Do not stop taking this medication without a doctor’s supervision. 

When taking Pristiq it is important to monitor behavior and contact a doctor immediately if there are signs of suicidal thoughts or behaviors, self harm, changes in behavior such as anger and agitation. 


Most common side effects may include:

  • Dry mouth, abdominal pain, diarrhea, constipation, bloating, nausea, vomiting
  • Dizziness, headache, vertigo
  • Chills
  • Lack of energy, sleeping problems or sleepiness
  • Coldness in the extremities (hands and feet)
  • Flu like symptoms
  • Changes in appetite and weight
  • Excessive sweating, rash or sensitivity to light
  • Yawning
  • Prickling sensation in the arms, hands, legs or feet
  • Hot flashes
  • Hair loss


Not all side effects are listed here. For further information, refer to the manufacturer’s product insert that comes with this medication.

Consult a doctor or healthcare provider before using this medication.

Pristiq is used to treat adult patients with major depressive disorder. It is a SNRIs inhibitor which helps increase the levels of serotonin and norepinephrine in the brain, resulting in an uplifting of mood and feeling.

  • What is the most common side effect of Pristiq?
    The most common side effects of Pristiq are nausea, vomiting, abdominal pain, diarrhea, constipation, feeling bloated, dry mouth. For further information regarding side effects, read the product insert and consult with a healthcare provider.
  • Is Pristiq a high risk medication?
    Pristiq comes with a box warning. A box warning is the highest form of a safety related warning that a medication can have issued by the FDA. When taking Pristiq there is a high risk of suicidal thoughts and behaviors, self harm and a risk of harm to others. It is important to monitor patients taking this medication and other forms of antidepressants.
  • Does Pristiq make you sleepy?
    Pristiq may cause sleepiness and drowsiness as a side effect. Other common side effects may include nausea, vomiting, constipation, diarrhea, dry mouth, dizziness. For further information regarding side effects, it is advised to consult with a doctor.
  • What to avoid while on Pristiq?
    While taking Pristiq it is advised not to drive or operate machinery. Also, it is advised not to drink alcohol while taking Pristiq. There are certain drugs that interact with Pristiq, therefore it is important to tell the prescribing doctor what other medications are being taken and what the patient's medical history is.
  • Does Pristiq cause weight gain?
    Pristiq may cause changes in the patient's appetite. This may cause weight gain in patients who have lost their appetite as a result of depression, or weight loss as a result of a decrease in the need to emotionally eat. This side effect may vary between patients. Overall, studies showed that the increase in weight as a side effect of taking Pristiq was not very significant.

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