Reported side effects include:
– menstrual cycle changes
– breast tenderness
– nausea or vomiting
– weight gain
– hair loss
– vaginal itching
– changes in skin color
The above may not be a complete list. Consult your doctor or contact us for other side effects. Your doctor expects that this treatment’s benefit is greater than the risk of side effects. Most people using this medication do not have serious or persistent side effects.
Estriol can also interact with grapefruit juice, and this may increase the risk of side effects.
There may be some irritation or itching of the skin in or around your vagina when you start to use Ovestin – this should clear up after a few days. If not, stop usage immediately and consult your doctor. If any of the above side-effects are persistent, stop the usage of Ovestin and consult with your medical practitioner.
Ovestin vaginal cream contains the active ingredient estriol, which is one of the naturally occurring forms of the primary female sex hormone estrogen (sometimes referred to as oestrogen) that is naturally found in the body. It is required for the treatment of vulvo-vaginal complaints related to estrogen deficiency.
Estrogens work by binding to estrogen receptors in the body. Estrogen receptor alpha (ERα) is primarily found in the vagina, breast tissue, and ovaries. Estriol can be used as hormone replacement therapy (HRT) for women after menopause, specifically targeting ERα receptors.