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  • US Name:

    Nexavar

  • Generic Names:

    Nexavar

  • Active Ingredients:

    Sorafenib

  • Brand Manufacturer:

    Bayer

  • Manufacturer Location:

    Germany

  • Click here to view Product Insert

  • Click here to view Product Insert

Nexavar

Prescription Required

Nexavar is prescribed to treat patients with advanced kidney, liver or thyroid cancers.

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Nexavar Brand 200mg
112 Tablets
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Our price: $1,980.00

*Please note all prices are in US dollars
Nexavar (generic name: sorafenib) is an oral medication that can be prescribed to treat:
  • A type of liver cancer called hepatocellular carcinoma (HCC) that cannot be removed by surgery
  • A type of kidney cancer called renal cell carcinoma (RCC)
  • A type of thyroid cancer called differentiated thyroid carcinoma (DTC) that can no longer be treated with radioactive iodine and is progressing

Dosage

Follow the prescribing doctor’s instructions. The usual dosage of Nexavar is 400 mg orally twice daily without food (at least 1 hour before or 2 hours after a meal)

This information is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

Please read the manufacturer’s information leaflet that comes with the medication before using it. Please bear in mind that not all possible side effects can be listed. 

Some of the side effects that have been reported when taking Nexavar include:

  • Diarrhea
  • Hair thinning or patchy hair loss
  • Tiredness or fatigue
  • Weight loss
  • Nausea/vomiting
  • Loss of appetite
  • Changes in taste
  • Dry skin
  • Mouth sores
  • Voice changes
  • Bleeding gums

If you experience any of these or any other unexpected side effects, seek medical attention from your prescribing physician.

Nexavar is prescribed to treat patients with a variety of advanced cancers. The main targets for treatment are:

  • Hepatocellular carcinoma (HCC), a type of liver cancer that primarily originates in the hepatocytes, which are the main functional cells of the liver. It is one of the most serious cancers in adults and requires careful management and treatment. Nexavar is prescribed when the tumors cannot be removed by surgery
  • Renal cell carcinoma (RCC), which is a type of kidney cancer that originates in the renal cortex. It is responsible for about 80% of all primary renal cancers. It is characterized by the uncontrolled growth of cells in the lining of the small tubes in the kidney, known as renal tubules.
  • Differentiated thyroid cancer (DTC), which includes papillary thyroid cancer and follicular thyroid cancer. Papillary thyroid cancer is the most common form of thyroid cancer in both children and adults and represents about 85 to 90 percent of all DTC diagnoses. Nexavar can be prescribed for adults in whom the cancer is progressing and who can no longer be treated with radioactive iodine.

Nexavar is only approved for adults and has not been tested on children.

  • What is the purpose of using Nexavar?
    Nexavar (sorafenib) is a medication that inhibits the growth of cancer cells. It is effective in treating liver, kidney and thyroid cancers. This oral tablet should be taken with water as prescribed.
  • Is Nexavar considered a TKI chemotherapy drug?
    Nexavar (sorafenib) does not fall under the chemotherapy category; however, it is utilized for cancer treatment. It is classified as targeted therapy. Administered orally in tablet form. Targeted therapies, like this specifically, combat certain types of cancer cells.
  • Under what drug category does sorafenib fall?
    Sorafenib belongs to a group of drugs known as kinase inhibitors. Its mechanism involves blocking a protein that triggers the proliferation of cancer cells, thereby impeding their growth and spread.
  • Can sorafenib reduce tumor size?
    Yes. MRI scans have demonstrated reduction in tumor size with early sorafenib treatment (nearly 40% by week 5 and up to 97% by week 15). This suggests that rapid tumor shrinkage on imaging serves as another indication of sorafenib's benefits.

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