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Neupro is prescribed to treat Parkinson’s Disease and Restless Legs Syndrome

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Neupro Brand 8mg
30 Patches
Our price: $347.00
Neupro Brand 6mg
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Neupro Brand 4mg
30 Patches
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28 Patches
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Neupro Brand 2mg
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Our price: $209.00

*Please note all prices are in US dollars
Neupro (rotigotine) is prescribed to treat Parkinson’s Disease (PD) and moderate-to-severe Restless Legs Syndrome (RLS). It is a dopamine agonist that works on the nervous system. Dopamine agonists mimic how dopamine works in the brain, so it reacts as if it is receiving dopamine. This means Neupro can reduce the symptoms but is not a cure.
Neupro is especially useful for treating early PD and for patients with PD and motor fluctuations. It can also be combined with L-DOPA in the treatment of late-stage PD.


Rotigotine is applied as a patch (rotigotine transdermal system) daily and worn for 24 hours. It should be applied to clean, dry, and healthy skin on the stomach, thigh, shoulder or upper arm, or on the side of the body between the ribs and the pelvis. It must be applied in different places each day, switching between the right and left sides and the upper and lower body. Neupro should not be applied to the same skin area more than once every 14 days.

This text is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

Neupro exhibits a similar safety profile to other DA meds, with nausea, sleepiness (somnolence), dizziness and impairment of voluntary movement (dyskinesia). There can also be skin reactions at the site of the patch.

The exact cause of Parkinson’s Disease (PD) is still not fully understood. However, researchers have explored theories, such as neural damage, exposure to environmental toxins, genetic predisposition and the effects of aging as potential factors contributing to the development of the condition.

In the neurological system, dopamine plays a role in maintaining a delicate balance among neurotransmitters to facilitate nerve and muscle cells’ coordination for movement. When there is a deficiency in the supply of dopamine, this balance is disrupted, leading to symptoms like tremors (shaking in the hands, arms, legs and jaw), muscle stiffness (rigidity), slowed movements and difficulties, with balance and coordination – all signs associated with PD.

  • How long can you use the Neupro rotigotine patch?
    The Neupro rotigotine transdermal patch is usually well tolerated for a year or more for patients being treated for Parkinson's Disease. At a stable dose, it provides sustained benefits for patients with moderate-to-severe restless legs syndrome for up to five years.
  • Where is the best place to put a rotigotine patch?
    It is best to apply the patch to an area of hair-free and healthy skin that is clean, dry, and intact. This includes areas on the stomach, thigh, shoulder or upper arm, hip, and either side of the body between the ribs and the hip,. The area must not be very oily, and free of skin irritation, scars or cuts.
  • How long does it take for rotigotine to work?
    Doctors usually start on a low dose of Neupro, and then alter the dose on a weekly review basis until the proper dose required to control the symptoms is found. It may take several weeks before the dose that controls symptoms best is reached.
  • Can the Neupro patch cause insomnia?
    For people being treated for Restless Legs Syndrome, the most common side effects of a rotigotine patch are reactions at the application site, nausea, difficulty falling and staying asleep, drowsiness and headaches. Please take time to read the manufacturer's Product Insert that comes with the medication. Not all side effects are listed here. Consult a healthcare provider if you experience these or other unexpected effects.

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