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Motegrity is a medication used to treat chronic idiopathic constipation in adults (CIC)

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Motegrity Brand 2mg
28 Tablets
Our price: $220.00
Motegrity Brand 1mg
28 Tablets
Our price: $143.00

*Please note all prices are in US dollars
Motegrity is a medication used to treat chronic idiopathic constipation (CIC) in adults. This type of constipation has an unknown cause. Motegrity contains Prucalopride, an active ingredient that is a selective serotonin type 4 (5-HT4) receptor agonist. It works by helping improve the movement of food during digestion from the stomach and intestines through the bowels.  

Motegrity side effects may include:

  • Abdominal pain and bloating in the stomach
  • Nausea 
  • Diarrhea 
  • Headache
  • Gas
  • Tiredness
  • Dizziness 

One side effect of Motegrity may be unusual changes in behavior and mood that manifest as depression, suicidal thoughts, and thoughts of hurting yourself. If you experience this, stop taking Motegrity immediately and contact the prescribing doctor. 

Motegrity may be prescribed to treat adult patients with chronic idiopathic constipation (CIC).

Motegrity is an oral tablet meant to be taken once a day with or without food or as advised by a doctor or healthcare provider. 

  • What does the drug Motegrity do?
    Motegrity is a medication used to treat chronic constipation of unknown cause when other treatments haven't been useful. It works by helping ease the movement of food in the digestive system during digestion.
  • Is Motegrity an SSRI?
    Motegrity is not an SSRI. Motegrity contains Prucalopride, a selective serotonin type 4 (5-HT4) receptor agonist.
  • How many days does it take for Motegrity to work?
    Motegrity usually takes up to a day to work. Studies showed that patients experienced a bowel movement after their first dose, while a few only experienced relief of symptoms after a few days of treatment.
  • Why is Motegrity so expensive?
    Motegrity is very expensive because it is a brand-name drug, not a generic drug, which tends to be less expensive.
  • How much is a 30-day supply of Motegrity?
    The cost of Motegrity varies according to the pharmacy. As of this publication (April 2024), the average price for a 30-day supply of the 1 mg oral tablet is $568. Currently, IsraelPharm sells 28 tablets of the 1 mg oral tablet for $130. *Prices are subject to change.

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