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Pitavastatin is a member of the blood cholesterol lowering medication class of statins. Like other statins, it is an inhibitor of HMG-CoA reductase, the enzyme that catalyses the first step of cholesterol synthesis.

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Livalo is an HMG-CoA reductase inhibitor known as a “statin.” It is used to treat patients with high blood cholesterol levels (hyperlipidemia) or imbalanced cholesterol and triglyceride levels. It is intended to be used in combination with a heart-healthy diet.    Livalo helps lower elevated total cholesterol (TC). In addition, it helps lower low-density lipoprotein cholesterol (LDL-C), also known as “bad” cholesterol, triglycerides (TG), apolipoprotein B (Apo B), and aids in increasing high-density lipoprotein cholesterol (HDL-C). Livalo can be used in patients 8 years or older with heterozygous familial hypercholesterolemia (HeFH), a type of high cholesterol that runs in the family.

Not all side effects are listed here. Consult a doctor or healthcare provider if you experience these or other unexpected effects. In addition, review the instructions included with the medication before starting treatment.


The most common side effects may include:

  • Constipation
  • Back pain
  • Diarrhea 
  • Myopathy (muscle pain, weakness, muscle spasms)
  • Rhabdomyolysis

Livalo is a medication used to lower LDL cholesterol levels and raise HDL cholesterol in patients with elevated cholesterol, imbalanced cholesterol, and triglycerides and patients with high cholesterol due to heterozygous familial hypercholesterolemia (HeFH). 


Livalo is a tablet taken orally once every day at the same time accompanied by food. Dosage varies between patients. 


Consult a doctor or healthcare provider before taking any medication, and inform them if any other medication is being taken. 

  • How much does Livalo lower cholesterol?
    Livalo (pitavastatin), taken along with a heart-healthy diet and regular exercise, will help improve overall cholesterol levels. In clinical trials, Livalo in 4 mg doses reduced LDL (bad) levels by up to 45%.
  • Do statins interfere with sleep?
    Researchers have found that fat-soluble statins like Livalo (pitavastatin) can cause insomnia or nightmares. They are able to more easily make their way across the blood-brain barrier, which isolates the brain from chemicals in the blood.
  • Can I take Livalo every other day?
    The maximum recommended dosage is 4 mg once daily, with or without food and at the same time. Lowering the dose without consulting a healthcare provider is not advised. If a dose is skipped or missed, it should be taken as soon as possible, but not double-dosed.
  • Will my cholesterol go up if I stop statins?
    If statin medication has been prescribed to lower cholesterol levels, it will probably be needed for life. Otherwise, cholesterol levels will likely go back up. Stopping the prescribed statin dosage can raise the risk of heart disease and other preventable health problems like stroke and heart attack.
  • What should you not take with Livalo?
    Discuss with a pharmacist or doctor when using Livalo in combination with other cholesterol drugs like niacin and fibrates. These may increase a patient's risk of serious muscle problems.
  • Can I drink coffee with statins?
    Caffeinated coffee blunts the myocardial protective effects of statins. Caffeine is a nonspecific adenosine receptor blocker, meaning drinking caffeinated coffee may block adenosine receptor activation.

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