Liptruzet / Atozet (
generic names: ezetimibe/atorvastatin) is a prescription medication known as
antihyperlipidemic. These combinations typically include two or more medications from different drug classes, each working through a unique mechanism to lower cholesterol levels and reduce the risk of heart disease.
Liptruzet is prescribed for people with high cholesterol when single-drug therapy is not enough to achieve the desired lipid-lowering effect or when the patient has multiple risk factors for cardiovascular disease. It belongs to the pharmacological class of lipid-lowering agents and is often prescribed for long-term use under medical supervision.
Ezetimibe reduces the amount of cholesterol absorbed in the intestines. Atorvastatin, a statin, lowers cholesterol production in the liver. Together, these two mechanisms significantly decrease low-density lipoprotein (LDL) cholesterol, commonly known as “bad” cholesterol, and increase high-density lipoprotein (HDL) cholesterol, known as “good” cholesterol. Read more detail about the
benefits and dangers of cholesterol on our blog.
Liptruzet is usually prescribed for patients who have not achieved good cholesterol levels with just diet and exercise or who need additional lipid-lowering therapy to reduce their cardiovascular risk.
For further information on treating high cholesterol and using combination therapies, visit this respected
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Dosage
It is essential to follow the prescribing doctor’s instructions carefully. The usual starting dose of Liptruzet is one tablet daily, with or without food. The specific dose depends on the patient’s medical condition, response to treatment, and other medications they may be taking.
Storage
Store Liptruzet at room temperature, between 20-25°C (68-77°F), away from moisture and light. Keep the medication in its original container, tightly closed, and out of reach of children. Do not use Liptruzet past the expiration date printed on the packaging.
Please read our friendly tips on handling medicine safely.
FAQ
Is it safe to take Liptruzet during pregnancy?
Liptruzet should not be used during pregnancy as it can harm the fetus. Women of childbearing age should use effective contraception while taking this medication and should consult with a doctor if they become pregnant while taking Liptruzet..
Can Liptruzet interact with other medications?
Yes, Liptruzet can interact with several medications, including certain antibiotics, antifungals, and other cholesterol-lowering drugs. Always inform the prescribing healthcare provider of all medications that are being taken.
Is it necessary to follow a special diet while taking Liptruzet?
Yes, to maximize Liptruzet’s effectiveness, it is recommended that you follow a cholesterol-lowering diet. This typically includes a diet low in saturated fats and cholesterol.
This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.Â
Read the information leaflet that comes with the medication.
If after taking Liptruzet a sudden allergic reaction (anaphylaxis) occurs, with symptoms like swelling of the face, tongue, or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering, or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.
Most people who use Atozet do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.
Some of the side effects that have been reported include:
- Headache
- Diarrhea
- Muscle pain
- Fatigue
- Nausea
Warnings:
- Liptruzet can cause muscle problems, including myopathy and rhabdomyolysis, which can lead to kidney damage. Symptoms include unexplained muscle pain, tenderness, or weakness, particularly if accompanied by fever or dark-colored urine.
- This medication may cause liver problems, which could be indicated by symptoms such as jaundice (yellowing of the skin or eyes), dark urine, severe stomach pain, or unexplained nausea and vomiting.
If these side effects occur, contact a healthcare provider immediately.
Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.
Liptruzet is FDA-approved to lower elevated total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides in adults. It can be used as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or alone if such treatments are unavailable.
Liptruzet can also be prescribed off-label to help reduce the risk of heart attack, stroke, and other cardiovascular events in patients with high cholesterol and additional risk factors.