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For visual reference only; actual product may vary
For visual reference only; actual product may vary
Kevzara (sarilumab) is an injectable prescription medicine for adults with moderate to severe rheumatoid arthritis (RA). It is used when other treatments, known as DMARDs, have not worked well enough. It helps reduce joint pain and inflammation.
Kevzara requires cold shipping. An additional fee is applied at checkout.
| Kevzara Brand | 150mg 2 Pre-Filled Pen |
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Our price: $1,795.00 |
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| Kevzara Brand | 200mg 2 Pre-Filled Pen |
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Our price: $1,795.00 |
Kevzara is an injectable prescription medication used to treat adults with moderate to severe rheumatoid arthritis. It is often prescribed when other common treatments have not provided enough relief. Kevzara belongs to a class of drugs known as biologics. Specifically, it is a human monoclonal antibody. This protein targets a specific part of the immune system. The goal is to reduce the inflammation that causes arthritis symptoms. By managing these symptoms, Kevzara can improve a person’s quality of life. It helps lessen joint pain, swelling, and stiffness. This can lead to better physical function for daily activities.
Kevzara works by blocking the activity of a protein called interleukin-6, or IL-6. This protein plays a key role in the inflammatory process of rheumatoid arthritis. In RA, the immune system mistakenly attacks healthy joints. IL-6 is one of the signals that promotes this inflammation. This inflammation leads to joint pain, swelling, and potential long-term damage. Kevzara specifically binds to the IL-6 receptor. By blocking this receptor, it interrupts the inflammatory signal. This action helps to calm the immune response in the joints. As a result, patients experience less inflammation and fewer arthritis symptoms.
Kevzara is intended for adults who have a diagnosis of moderate to severe rheumatoid arthritis. It is specifically for patients who have tried other medications first. These other drugs are called disease-modifying antirheumatic drugs (DMARDs), like methotrexate. If a patient has not responded well or is intolerant to these drugs, Kevzara may be an option. It can be used alone as a monotherapy. More commonly, it is used in combination with methotrexate for greater effect. A rheumatologist will determine if Kevzara is the right choice for a patient’s treatment plan.
Kevzara is administered as an injection just under the skin, which is called a subcutaneous injection. The standard dosing schedule is typically once every two weeks. Your doctor will prescribe the exact dose that is right for you. Patients can be taught how to inject the medicine themselves. Common injection sites include the thigh, abdomen, or the back of the upper arm. It is important to rotate injection sites with each dose. Do not inject into skin that is tender, bruised, red, or hard. Always follow your healthcare provider’s instructions for administration.
Kevzara may cause some side effects, although not everyone will get them. The most common side effects are related to the immune system. These can include a runny or stuffy nose, sore throat, or sinus infections. Other reported side effects are urinary tract infections and cold sores. Because Kevzara affects the immune system, it can increase your risk of serious infections. Your doctor will monitor you for any signs of infection. Your blood may also be tested regularly. This checks for changes in liver enzymes, cholesterol, and blood cell counts. Tell your doctor about any side effect that bothers you.
IsraelPharm offers a reliable and convenient way to purchase your prescription medications like Kevzara. We provide authentic brand-name drugs sourced from trusted manufacturers, ensuring you receive the highest quality treatment. Our streamlined online ordering process is simple and secure. We are committed to making your medication more affordable. You can save money compared to high US pharmacy prices. Our customer service team is available to help with your order. We also ensure that temperature-sensitive medications like Kevzara are shipped with proper cold-chain packaging to maintain their effectiveness during transit.
Most patients using Kevzara do not have serious side effects. However, some common adverse effects have been reported. Contact your doctor if these symptoms persist or worsen.
Because Kevzara can lower your ability to fight infections, you should tell your doctor immediately if you develop a fever, chills, or other signs of an infection.
Kevzara is primarily used for the treatment of moderate to severe rheumatoid arthritis (RA) in adult patients. It is indicated for individuals who have had an inadequate response or intolerance to one or more disease-modifying antirheumatic drugs (DMARDs).
Kevzara may begin to relieve rheumatoid arthritis symptoms within a few weeks of starting treatment. Some patients report feeling better after the first few injections. However, it can take up to three months to experience the full benefits of the medication. The response time varies for each individual. Your doctor will monitor your progress to see how well the treatment is working for you.
Kevzara should not be started if you have an active, serious infection. Because this medication affects your immune system, it can make it harder for your body to fight the infection. Before starting treatment, your doctor will screen you for any existing infections, including tuberculosis (TB). If you develop signs of an infection while on Kevzara, contact your doctor immediately.
While taking Kevzara, your doctor will order regular blood tests to monitor your health. These tests are important for your safety. They typically check your white blood cell count (neutrophils), platelet count, liver enzyme levels, and cholesterol levels. Kevzara can sometimes cause changes in these lab results. The tests are usually done before starting treatment and then every 4 to 8 weeks.
Kevzara is not commonly associated with weight gain as a direct side effect in clinical trials. However, rheumatoid arthritis and its treatments can affect people differently. Some individuals might experience changes in weight due to improved appetite or reduced inflammation and pain, which allows for more activity. If you notice significant, unexplained weight changes while taking Kevzara, you should discuss it with your healthcare provider.
Kevzara is very frequently prescribed in combination with methotrexate for treating rheumatoid arthritis. Studies have shown that using these two medications together can be more effective at controlling RA symptoms than using either one alone. If you cannot take methotrexate due to side effects or other reasons, your doctor may prescribe Kevzara as a standalone therapy (monotherapy).
Kevzara must be stored in the refrigerator between 36°F and 46°F (2°C and 8°C). Keep it in its original carton to protect it from light. Do not freeze the medication. Before an injection, you can let it sit at room temperature for about 30 minutes. Once a pen or syringe has been stored at room temperature, it must be used within 14 days and not put back in the fridge.
If you miss a dose of Kevzara, you should take it as soon as you remember. After that, take your next dose at your regularly scheduled time. Do not take two doses at once to make up for a missed one. If you are unsure what to do, it is best to contact your doctor or pharmacist for guidance on how to get back on your dosing schedule.
Kevzara may weaken your immune system, so you should not receive live vaccines while taking it. Live vaccines contain a weakened form of a virus or bacteria. Examples include the measles, mumps, rubella (MMR) and chickenpox vaccines. It is recommended to have all your necessary vaccinations up to date before you start your Kevzara treatment. Always talk to your doctor before getting any vaccine.
Yes, Kevzara is a type of medication known as a biologic. Biologics are complex proteins made from living sources, such as cells. Kevzara is a specific type of biologic called a monoclonal antibody. It is designed to target a very specific part of the immune system—the interleukin-6 (IL-6) receptor—to reduce the inflammation that drives rheumatoid arthritis symptoms and joint damage.
Kevzara is currently only approved by the FDA for the treatment of moderate to severe rheumatoid arthritis in adults. It has not been approved for other types of arthritis, such as osteoarthritis or psoriatic arthritis. The mechanism of blocking IL-6 is specific to the inflammatory pathways involved in RA. Your doctor will determine the best treatment for your specific condition.
There is no direct interaction listed between Kevzara and alcohol a Cautious consumption is advised. Both alcohol and Kevzara can potentially affect the liver. Your doctor will monitor your liver function with blood tests. Heavy alcohol use is not recommended. It is always best to discuss your alcohol consumption with your doctor before starting any new medication to ensure it is safe for you.
Your healthcare provider will teach you how to properly inject Kevzara at home. The injection is given under the skin (subcutaneously) in your thigh or abdomen. You should rotate the injection site each time to avoid irritation. Let the pre-filled pen or syringe warm to room temperature for 30 minutes before use to make the injection more comfortable. Always follow the specific instructions provided.
Kevzara can cause an increase in blood cholesterol levels in some patients. This was a side effect noted during clinical trials. Because of this, your doctor will perform blood tests to check your cholesterol and other lipid levels before you start taking Kevzara. They will continue to monitor these levels periodically during your treatment to ensure they stay within a healthy range.
Yes, you can travel with your Kevzara medication. It is a temperature-sensitive drug, so it must be kept cold. You will need to transport it in a travel cooler with ice packs to maintain the required temperature. Be sure to keep the medication in its original packaging with the prescription label. Always carry a letter from your doctor explaining your need for the medication, especially when flying.
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