For visual reference only; actual product may vary
For visual reference only; actual product may vary
Evenity (romosozumab) is a prescription treatment for osteoporosis in postmenopausal women with a high risk for bone fractures. It works by both building new bone and decreasing bone loss to strengthen bones and help prevent fractures. This medication is given as two injections once a month.
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The most common side effects associated with Evenity treatment include joint pain and headaches. These symptoms often decrease over time.
Evenity may cause more serious side effects. Treatment carries an increased risk of heart attack, stroke, or death from a cardiovascular event. Seek emergency medical help if you experience:
Other serious side effects can occur. Contact your doctor immediately if you have signs of:
Evenity is a preventative treatment for osteoporosis in women after menopause. It is specifically for those who are at a high risk of bone fracture.
Osteoporosis is a condition where the body loses bone mass faster than it can be replaced. This leads to weak, brittle bones that can break easily. It is very common in women after menopause. Evenity helps by not only slowing down bone loss but also by actively building new bone to reduce the risk of fractures.
Evenity begins to increase bone formation shortly after you receive your first dose. Patients can see significant improvements in bone mineral density within the first few months. However, the full benefits of the treatment are realized after completing the entire 12-month course. The goal is to strengthen your bones over this period to provide long-term protection against fractures. Your doctor will monitor your progress throughout the treatment cycle.
The standard treatment duration for Evenity is twelve months. You will receive two injections from your healthcare provider once every month for a total of one year. It is crucial to complete the full 12-dose course to get the maximum benefit from the medication. After finishing the course, your doctor will switch you to a different osteoporosis medication to maintain the new bone you have built.
Evenity must be administered by a healthcare professional. It is given as two subcutaneous injections, one right after the other, to provide the full monthly dose. You cannot give these injections to yourself at home. They will be administered at your doctor’s office or another clinical setting. This ensures the medication is given correctly and safely every time you receive your monthly treatment.
Evenity requires a consistent monthly dosing schedule for the best results. If you miss a scheduled appointment for your Evenity injections, you should contact your healthcare provider as soon as possible to reschedule. They will help you get your next dose and adjust the schedule for future doses. Do not wait for your next regularly scheduled appointment, as this could reduce the treatment's effectiveness over time.
Evenity treatment works best when your body has enough calcium and vitamin D. Your doctor will instruct you to take daily supplements of both calcium and vitamin D throughout your 12-month treatment course. These nutrients are essential building blocks for forming new, strong bone tissue. Insufficient levels can limit the effectiveness of the medication. Follow your doctor's recommendation for specific supplement dosages.
Evenity could potentially harm an unborn baby and it is not known if it passes into breast milk. You should not use Evenity if you are pregnant, planning to become pregnant, or are currently breastfeeding. It is important to discuss your family planning and health status with your doctor before starting this treatment. They can advise you on the best course of action for your osteoporosis.
The most common side effects reported with Evenity treatment are joint pain (arthralgia) and headaches. These symptoms are usually mild to moderate and may become less frequent over time. If these side effects persist or become bothersome, you should speak with your healthcare provider. They can help you manage these symptoms while you continue your treatment for osteoporosis.
Evenity treatment has a boxed warning for an increased risk of heart attack, stroke, and death from cardiovascular causes. You should not take Evenity if you have had a heart attack or stroke within the previous year. Your doctor will evaluate your cardiovascular risk before prescribing this medication. It is essential to discuss your heart health and any related conditions with them.
Evenity has been linked to a rare but serious jaw problem called osteonecrosis of the jaw (ONJ). For this reason, it is crucial that you inform your dentist that you are being treated with Evenity before any dental procedures. It is also recommended to practice good oral hygiene, including regular brushing, flossing, and dental check-ups, to help minimize your risk while on this medication.
Evenity must be kept refrigerated at a temperature of 36°F to 46°F (2°C to 8°C). It should be stored in its original carton to protect it from light. Do not freeze or shake the medication. Before an injection, the carton can be left at room temperature for at least 30 minutes to make the injection more comfortable, but it should not be left out for more than 30 days.
Evenity is not known to have a direct interaction with alcohol. However, healthcare providers generally recommend moderation. Chronic and heavy alcohol consumption is a known risk factor for osteoporosis and can increase the risk of falls, which could lead to fractures. It is best to discuss your alcohol consumption with your doctor before starting treatment to ensure it does not interfere with your health goals.
After you complete your 12-month Evenity treatment course, your doctor will transition you to a different type of osteoporosis medication. This is usually an anti-resorptive drug, which helps maintain the new bone density you have gained and prevents future bone loss. Evenity builds the bone, and the next medication helps to preserve it. This follow-up treatment is a critical step in a long-term strategy to manage osteoporosis.
Evenity should not be given to patients who currently have low blood calcium, a condition known as hypocalcemia. Before you start your treatment, your doctor will test your blood to ensure your calcium levels are normal. They must correct any low calcium levels before your first injection. You will also be advised to take calcium and vitamin D supplements during your treatment to prevent this issue.
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