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Eucrisa is a topical ointment for atopic dermatitis in adults and children aged three months and older.

Prescription Required
Staquis Ointment
60 Grams
*Please note all prices are in US dollars

Eucrisa (generic name: crisabole) is a 100% steroid-free ointment for people with mild-to-moderate atopic dermatitis (eczema). It can be prescribed for adults and pediatric patients three months of age and older. 

Crisaborole acts deep within skin cells to target PDE4 (phosphodiesterase 4). It is a PDE4 inhibitor.


Follow the doctor’s instructions and refer to the enclosed Patient Information leaflet for more information.

The standard dosage is to apply a thin layer twice daily to affected areas. Once the desired clinical effect is achieved, a doctor may reduce the dosage to once daily.

Eucrisa is for topical (external) use only. Do not use it in the eyes, mouth, or vagina.

Some people have reported skin sensations such as burning or stinging at the application site. If this persists or worsens, consult with a healthcare provider.

Reactions such as contact urticaria (hives), severe itching, swelling, and abnormal redness at the application site or another site may be symptoms of hypersensitivity to crisabole. If these occur, discontinue Eucrisa immediately and consult with a healthcare provider, informing them that crisabole has been used.

Please note that not all possible side effects can be listed. If you experience any of these or any other unexpected side effects, seek medical attention promptly. 

Symptoms of atopic dermatitis (eczema) include severe itching, red and dry patches of skin, rashes that may ooze, weep a clear fluid, or bleed when scratched. Eczema is visible on the skin’s surface, but there may also be irritation below that can’t be seen. Eucrisa works both above and below the skin to treat eczema.

  • Is Eucrisa a steroid?

    Eucrisa (crisabole) is a 100% steroid-free topical ointment. It was the first steroid-free ointment treating people with mild-to-moderate eczema for adults and kids as young as three months old. It is for topical use only.
  • What does a PDE4 inhibitor do?

    PDE4 inhibitors like crisabole work to reduce inflammation. As a treatment, it is beneficial for people with eczema to manage inflammation, making outbreaks less frequent and severe.
  • What topical phosphodiesterase 4 inhibitors are used for atopic dermatitis?

    The FDA has approved Eucrisa as the only topical PDE-4 inhibitor for atopic dermatitis. It's available as an ointment in a 2% concentration. The ointment also helps keep the affected skin areas moisturized.
  • Why should you avoid steroids for eczema?

    Topical steroids may increase the likelihood of skin infections because they inhibit some immune functions in the skin. Eucrisa is the only topical PDE-4 inhibitor for atopic dermatitis that is completely steroid-free.


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