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  • US Name:

    Estrogel Topical Gel

  • Israeli Names:

    Oestrogel Topical Estradiol Gel

  • Active Ingredients:

    Estradiol (E2)

  • Brand Manufacturer:


  • Manufacturer Location:


Estrogel Topical Gel

Estradiol is the natural hormone estrogen. Recommended areas for application: arm, shoulder or the middle inner thigh. The gel should be applied either on the outer arm and shoulder of both arms, or in the inner middle area of both thighs. Avoid applying near the breasts and genital area.

Prescription Required
Oestrogel Topical Cream
1 80g Tube
*Please note all prices are in US dollars

EstroGel is a topical gel for women suffering from more postmenopausal severe symptoms due to hormone deficiency. It is an alcohol-based gel, specially formulated for topical use, prescribed as a supplement to replace falling estrogen hormone levels. EstroGel topical gel contains estradiol – the most potent form of the hormone estrogen.

The main ingredient in EstroGel is estradiol, which helps reduce the symptoms of menopause. It is absorbed directly through the skin at the applied site. Estradiol has a direct effect on the cervix, vagina, and vulva.

Reported side effects of EstroGel include:
– nausea or vomiting
– loss of appetite
– swollen breasts
– acne or skin color changes
– vaginal pain, dryness or discomfort
– decreased sex drive or difficulty having an orgasm
– swelling
– weight gain
– migraine headaches
– dizziness
– depression
– break-through bleeding
– vaginal itching or discharge

The above is not a complete list of side effects, and others may occur. Talk to your doctor or call us for advice about side effects. Do not use EstroGel if you are pregnant or breastfeeding. Your doctor expects that this treatment’s benefit is greater than the risk of side effects. Most people using this medication do not have serious or persistent side effects.

There may be some irritation or itching of the skin in or around your vagina when you start to use EstroGel – this should clear up after a few days. If not, stop usage immediately and consult your doctor. If any of the above side-effects are persistent, stop the usage of EstroGel and consult with your medical practitioner.

EstroGel is a recommended hormonal replacement therapy (HRT) treatment for more severe vulvo-vaginal complaints related to estrogen deficiency in menopausal women.

It also has benefits in preventing postmenopausal osteoporosis, which carries an increased risk for bone fractures. EstroGel is not to be applied to the vagina or breasts.

  • What does estrogel gel do?

    Estrogel Topical Gel (estradiol) supplies the female hormone estrogen. The hormone is absorbed through the skin. Estrogel Topical Gel is used by women to help reduce some symptoms of menopause, such as vaginal dryness and hot flashes.
  • When should I apply estrogel gel?

    Estrogel Topical Gel should be applied after a bath or shower. It is recommended to leave as much time as possible between applying the gel and swimming.
  • Where should I put my estrogel gel?

    Apply Estrogel Topical Gel to clean, dry, and unbroken skin. Spread it thinly over the inside and outside of the upper arm or shoulder. Do not apply the gel directly on the breasts or in or around the vagina.
  • How quickly does estrogel gel work?

    Estrogel Topical Gel can start to relieve the symptoms of menopause, which are caused by an estrogen deficiency, within a few weeks. Full benefits may take several months.
  • What happens if you use too much estrogel gel?

    The effects of overdosing with Estrogel Topical Gel could be breast tenderness, nausea and vaginal bleeding. If these symptoms persist or worsen, discontinue use and consult with a doctor immediately.


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