What is the use of apalutamide?

Erleada (apalutamide) can treat adult men with prostate cancer that has begun to spread around the body and that responds to treatments that lower testosterone levels (androgen deprivation). It also treats non-metastatic prostate cancer (cancer that has not yet started to spread) but is resistant to hormone therapy.

What is the life expectancy with apalutamide?

Erleada does not cure prostate cancer, but has been shown in multiple studies to extend life expectancy by several years. It is also more effective than the alternative treatments available, and showed a statistically significant difference in survival rates. Additional treatments such as surgery or radiation therapy may also become necessary.

What happens when apalutamide stops working?

If apalutamide has been used to treat prostate cancer, and it is discontinued either because it has stopped working or due to adverse side effects, it may not be possible to switch to other hormone therapies. This includes abiraterone, enzalutamide, or darolutamide. Research suggests that anyone who has already had one of these drugs doesn't respond well to the other drugs.

Can I drink alcohol while taking apalutamide?

Drinking moderate amounts of alcohol does not appear to affect the safety or effects of Erleada.

How long is apalutamide treatment for?

Erleada is usually taken for as long as it is effective in slowing cancer growth, or side effects begin to make it unacceptable. In the clinical trials on adults with nmCRPC, some patients were using apalutamide for more than three years.

is erleada a form of chemotherapy

Erleada is not a chemotherapy drug. It is a form of hormone therapy that reduces the levels of androgen hormones (principally testosterone) in the body. Research has found that men with higher testosterone levels also had clinically elevated Prostate-Specific Antigen (PSA) levels, which is an indicator of prostate enlargement. On the other hand, chemotherapy drugs work by attacking cells that are growing rapidly.

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US Name:

Erleada
Alternative Names:

Erleada
Active Ingredients:

Apalutamide
Brand Manufacturer:

Janssen
Manufacturer Location:
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Erleada ^*

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Erleada treats adult men with metastatic prostate cancer that responds to androgen deprivation therapy and also to non-metastatic prostate cancer that is resistant to hormone therapy.

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Erleada Brand	60mg 120 Tablets	- Erleada – Brand, Erleada, 60mg, 120, Tablets, 99999, Janssen, 2125 + 0	Our price: $3,146.00

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Description
Side Effects
Indications
FAQ
Video

Erleada (apalutamide) is a medication used to treat men with certain types of prostate cancer. It treats metastatic hormone-sensitive prostate cancer (mHSPC), which is a form of cancer that originates in the prostate gland but has spread (metastasized) but still responds to hormone therapy that lowers testosterone levels (androgen deprivation therapy). It also treats prostate cancer that has not spread but does not respond to hormone therapy (non-metastatic castration-resistant prostate cancer, or nmCRPC).

Apalutamide belongs to a class of drugs known as anti-androgens (anti-testosterone). It works by blocking the effects of testosterone to slow the growth and spread of prostate cancer.

Dosage

The dosage and regimen are set by the prescriber. It is recommended to take the prescribed dose at the same time each day. If a scheduled dose is missed, it can be made up on the same day, but do not make up for a missed dose the following day by double-dosing. The tablets can be taken with or without food and should be swallowed whole, not chewed or crushed.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.

Read the information leaflet that comes with the medication.

If after taking Erleada there is a sudden allergic reaction (anaphylaxis), with symptoms like swelling of the face, tongue or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.

Most people who use Erleada do not experience any negative side effects. Doctors prescribe Erleada because they assess that the benefits that such treatment yields outweighs any likely unwanted effects.

Some of the side effects that have been reported include:

feeling exhausted
joint pain
rash
decreased appetite
weight loss
high blood pressure
hot flash
diarrhea

Less common but more serious side effects can include chest pain or discomfort; shortness of breath; numbness or weakness of the face, arm, or leg, especially on one side of the body; difficulty talking or understanding; visual disturbances; dizziness; loss of balance or coordination; or difficulty walking. If any of these side effects are felt, report to a doctor or clinic as soon as possible.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

Prostate cancer is common in adult men and may be diagnosed early. Diagnosis is done by a biopsy that returns one of two possible positive results:

Metastatic hormone-sensitive prostate cancer (mHSPC) is prostate cancer that has spread to other parts of the body, but which can still respond to medical or surgical treatment that lowers testosterone levels (androgen deprivation). The areas of the body where prostate cancer most often spreads to are the bones, adrenal glands, liver, and lungs.
Non-metastatic castration-resistant prostate cancer (nmCRPC) is prostate cancer that has not spread to other parts of the body, but no longer responds to a medical or surgical treatment that lowers testosterone.

The main symptoms of early prostate cancer can include a need to urinate more frequently during the night, with a need to rush to the toilet. There may be difficulty in starting to urinate, with straining or taking a long time along with a weak flow and being left with a feeling that the bladder has not emptied fully. There may also be traces of blood in the urine or semen.

Erleada (apalutamide) can treat adult men with prostate cancer that has begun to spread around the body and that responds to treatments that lower testosterone levels (androgen deprivation). It also treats non-metastatic prostate cancer (cancer that has not yet started to spread) but is resistant to hormone therapy.
Erleada is not a chemotherapy drug. It is a form of hormone therapy that reduces the levels of androgen hormones (principally testosterone) in the body. Research has found that men with higher testosterone levels also had clinically elevated Prostate-Specific Antigen (PSA) levels, which is an indicator of prostate enlargement. On the other hand, chemotherapy drugs work by attacking cells that are growing rapidly.

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