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Pimecrolimus is absorbed into the skin, where it works by blocking the production of inflammatory chemicals called cytokines. These are produced by white blood cells in the skin as part of the body’s immune response to allergy or irritation, and are part of a cascade of events in the skin that results in the irritated area becoming inflamed – red, swollen and itchy. As pimecrolimus stops the white blood cells in the skin from producing cytokines, it reduces inflammation in the skin. Pimecrolimus cream is used to reduce the inflammation of the skin seen in eczema (atopic dermatitis). This relieves the symptoms of this condition, such as redness and itching.
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