Dovato (generic names: dolutegravir and lamivudine) is an antiviral medication that is prescribed to treat human immunodeficiency virus 1 (HIV-1) in adults and in adolescents (12 years of age and older) who weigh at least 90 pounds (40 kilos.) Dovato contains two active ingredients. Dolutegravir belongs to a group of anti-retroviral medicines that block the enzyme HIV integrase, which is necessary for the HIV virus to invade the cell’s DNA and for the infected cells to spread. Lamivudine belongs to a group of anti-retroviral medicines called nucleoside analog reverse transcriptase inhibitors (NRTIs). Dovato does not cure HIV infection; it keeps the amount of virus in the body at a low level. This helps maintain the number of CD4 cells in the blood. CD4 cells are a type of white blood cells that are important in helping the body fight infection.

Dosage

The dosage and regimen are set by the prescribing doctor, and it is important to adhere to this plan. The usual dose is one tablet, which can be taken with or without food.

Caution

Avoid running out of this medication. Without the regular dose, there may be a flare-up in which symptoms worsen. Dovato should be taken at least two hours before or six hours after using antacids, laxatives, or other medications containing aluminum, magnesium, or buffered compounds. Calcium supplements, iron supplements, and multivitamins should be taken alongside Dovato, preferably with a meal.

Storage

Store at or below 30°C / 88ºF, protected from light and moisture.  Read our tips on handling medicine safely. FAQ

What happens when you stop taking Dovato?

Stopping Dovato use abruptly, without the proper medical checkups, could cause the viral load to become worse than before.

Can I drink alcohol when on Dovato?

Consult with a healthcare practitioner or pharmacist to find out more about the implications of alcohol while taking Dovato.

What does it mean to be undetectable with Dovato?

This means the blood’s viral load is below the levels a lab test detects.