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  • US Name:


  • Israeli Names:

    Cymbalta, Yentreve

  • Active Ingredients:


  • Brand Manufacturer:


  • Manufacturer Location:



This drug is used to treat depression and anxiety.

Prescription Required
28 Capsules
28 Capsules
56 Capsules
56 Capsules
*Please note all prices are in US dollars

Cymbalta® (duloxetine) is an antidepressant that affects chemicals in the brain that may become unbalanced. It is part of a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs).

Cymbalta can cause some minor side effects, including dry mouth, drowsiness, tired feeling, mild nausea or loss of appetite or constipation. If these persist or get worse, talk to a healthcare provider of pharmacist.

If you have any of the folloing signs of an allergic reaction show, seek emergency help immediately and tell the doctors that you are taking duloxetine medication:

  • skin rash or hives
  • difficulty breathing
  • swelling of your face, lips, tongue, or throat.

Any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself should be reported to the prescribing doctor.

Pay attention to the “Black Box Warning” in the Cymbalta package. Like most antidepressants, Cymbalta may trigger suicidal thoughts and behavior in children, adolescents and adults under the age of 24. Therefore, patients should be monitored closely for changes in mood and behavior and the emergence of such symptoms.

Failure to read and follow the information on the manufacturer’s Product Insert leaflet that comes with the medication can carry serious health risks. Please be aware that not all possible side effects can be listed here. If you experience any of these or other unexpected side effects, consult a healthcare provider immediately.

Cymbalta is indicated for the treatment of major depressive disorder (MDD)and Cymbalta is indicated for the treatment of generalized anxiety disorder Cymbalta is indicated for the management of neuropathic pain (DPNP) associated with diabetic peripheral neuropathy Cymbalta is indicated for the management of fibromyagia and the management of chronic musculoskeletal pain

  • What is Cymbalta usually prescribed for?

    Cymbalta (duloxetine) is usually prescribed to treat MDD (major depressive disorder) and some forms of long-term pain in adults. Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SNRI) that blocks the uptake of both serotonin and norepinephrine, chemicals that may trigger depression.
  • Does Cymbalta make you gain weight?

    Weight gain is a recorded side effect of Cymbalta in long-term treatment. It can, however, also cause weight loss during the first few months. Doctors advise patients to manage their weight while taking Cymbalta by using healthy lifestyle choices.
  • Can I have alcohol with Cymbalta?

    Cymbalta and other SSNRI drugs should not be taken with alcohol. Combining an antidepressant with alcohol can have very serious side effects.
  • What happens if I miss a day of Cymbalta?

    It’s recommended to take the prescribed dose of duloxetine once a day at a regular time. If a dose is missed, it should be taken as soon as possible after the scheduled time, but not less than 12 hours before the next dose. In that case, the dose should be skipped, and only a regular dose should be taken at the scheduled time. It should not be made up with double-dosing.
  • Will Cymbalta keep me awake at night?

    Insomnia is one of the common side effects of Cymbalta. If the difficulty persists or worsens, report this to a healthcare professional for advice.


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