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For visual reference only; actual product may vary
US Name:
Combigan
Alternative Names:
Combigan
Active Ingredients:
Brimonidine-0.2% and Timolol-0.5%
Brand Manufacturer:
Allergan
Manufacturer Location:
USA
Click here to view Product Insert
Click here to view Product Insert
For visual reference only; actual product may vary
Combigan is a prescription eye drop combining brimonidine and timolol to lower elevated intraocular pressure (IOP). It is used to treat open-angle glaucoma and ocular hypertension, reducing the risk of optic nerve damage. This dual-action formula offers greater pressure reduction than either medicine used alone.
| Combigan Brand | 0.2%, 0.5% 1 - 5ml Bottle |
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Our price: $43.00 |
Combigan is a combination prescription eye drop used to lower intraocular pressure (IOP) in people with open-angle glaucoma or ocular hypertension. It contains two active ingredients, brimonidine tartrate and timolol maleate, which work together to reduce the high pressure inside the eye. By controlling eye pressure, Combigan helps to prevent damage to the optic nerve and potential vision loss, which are the primary risks associated with untreated glaucoma.
Combigan works by combining two different medications that decrease the amount of fluid in the eye and reduce pressure. The first ingredient, brimonidine, is an alpha-adrenergic agonist that both reduces the production of the eye’s natural fluid (aqueous humor) and increases its outflow. The second ingredient, timolol, is a beta-blocker that primarily works by decreasing the production of aqueous humor. This dual mechanism makes Combigan more effective at lowering IOP than either medication used on its own, providing comprehensive pressure control.
Combigan is for adults diagnosed with open-angle glaucoma or ocular hypertension who need to lower their intraocular pressure. It is often prescribed when a single medication has not been effective enough at controlling a patient’s IOP. A healthcare provider or optometrist diagnoses these conditions by measuring eye pressure. This medication is intended for patients who can safely tolerate both active ingredients and do not have contraindications related to beta-blockers or alpha-agonists, such as certain respiratory or heart conditions.
The standard dosage for Combigan is one drop in the affected eye or eyes twice a day, administered approximately 12 hours apart, or as directed by your doctor. To apply the drops correctly, first wash your hands. Tilt your head back, look up, and gently pull down your lower eyelid to create a small pocket. Squeeze one drop into this pocket without letting the dropper tip touch your eye, eyelid, or any other surface. After instilling the drop, close your eye and gently press your finger against the inside corner for 1-2 minutes to prevent the medication from draining into your tear duct. If you use other eye drops, wait at least five minutes between applications.
The most common side effects of Combigan include temporary eye redness, burning, stinging, itching, and a feeling of something being in the eye. Because the active ingredients can be absorbed into the bloodstream, some people may also experience systemic effects such as dry mouth, drowsiness, or fatigue. Other ocular effects can include inflammation of the eyelid or visual disturbances. Most side effects are mild and temporary. However, if you experience severe discomfort, an allergic reaction (intense itching and swelling), or persistent symptoms, you should consult your doctor immediately.
IsraelPharm offers a safe, affordable, and convenient way to purchase your Combigan prescription online from a trusted source. We provide access to genuine, brand-name medications like Combigan from leading manufacturers such as Allergan at competitive prices, helping you save money on your essential treatments. Our licensed pharmacists ensure every prescription is reviewed for safety and accuracy. With our user-friendly online platform and reliable international shipping, you can have your medication delivered directly to your door, ensuring you never miss a dose.
While many users do not experience issues, Combigan can cause side effects. The most common effects are typically localized to the eye:
Because the active ingredients can be absorbed systemically, other effects are possible. Contact your doctor if you experience any persistent or bothersome side effects. This is not a complete list.
Combigan is indicated for the treatment of elevated intraocular pressure (IOP) in patients with:
It is used to reduce the risk of optic nerve damage and potential vision loss associated with these conditions.
You should notice a reduction in eye pressure within a few hours of the first dose. The peak effect of Combigan typically occurs about two hours after administration. Consistent twice-daily use is necessary to maintain a stable, lower intraocular pressure and effectively manage your condition over the long term.
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular schedule. Do not double up by instilling extra drops to make up for the missed dose, as this can increase the risk of side effects.
Yes, but you must space them out correctly. If you are using other eye medications, wait at least 5 minutes between applying each type of drop. This prevents one medication from washing out the other and ensures that both can work effectively. Always follow your doctor's specific instructions for your treatment regimen.
Temporary blurred vision can be a side effect of Combigan, especially right after you apply the drops. This usually resolves within a few minutes. For your safety, avoid driving or operating heavy machinery until your vision has cleared. If blurred vision is persistent or severe, you should contact your healthcare provider.
Store Combigan at room temperature, between 59-77°F (15-25°C), in an upright position. Keep the bottle tightly closed in a clean, dry place away from direct heat and light. Do not freeze the medication. As with all medicines, be sure to keep it safely out of the reach of children and pets.
No, Combigan is not known to cause changes in iris color. This side effect is associated with a different class of glaucoma medications called prostaglandin analogs. The active ingredients in Combigan, brimonidine and timolol, work through different mechanisms and do not typically affect the pigmentation of the eye.
You should remove your contact lenses before applying Combigan drops. The preservative in the medication can be absorbed by soft contact lenses and may cause irritation. Wait at least 15 minutes after using the drops before reinserting your lenses. This helps ensure both comfort and effectiveness of the treatment.
Combigan and Lumigan are both used to treat glaucoma but work differently. Combigan is a combination drop (brimonidine/timolol) that reduces eye pressure by decreasing fluid production. Lumigan (bimatoprost) is a prostaglandin analog that works primarily by increasing the outflow of fluid from the eye. Your doctor chooses the best one for you.
Yes, drowsiness and fatigue are possible side effects of Combigan. This is because the active ingredients, particularly the beta-blocker timolol, can be absorbed into the bloodstream and have systemic effects. If you experience significant tiredness, be cautious when driving or performing other tasks that require alertness.
An allergic reaction to Combigan typically involves symptoms in and around the eye. You might experience intense itching, persistent redness that worsens over time, and swelling of the eyelids. If you notice these symptoms, especially after starting treatment, stop using the drops and contact your doctor immediately.
Glaucoma is often a chronic condition that requires long-term management to prevent vision loss. If Combigan is effective for you, your doctor will likely recommend continuing it indefinitely. Regular check-ups are essential to monitor your eye pressure and ensure the treatment remains appropriate for you. Never stop treatment without consulting your doctor.
Combigan contains timolol, which is a beta-blocker. In eye drop form, timolol works to lower intraocular pressure by significantly reducing the production of aqueous humor—the fluid inside your eye. This action is a key part of how Combigan effectively manages conditions like open-angle glaucoma and ocular hypertension.
Combigan is dosed twice daily, about 12 hours apart. Most people establish a routine of one drop in the morning and one drop in the evening. This consistent schedule ensures stable control over your eye pressure throughout the day and night. Follow the specific schedule recommended by your healthcare provider.
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