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  • US Name:


  • Israeli Names:


  • Active Ingredients:

    Brimonidine-0.2% and Timolol-0.5%

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Combigan is a combination therapy for Glaucoma.

BrandCombigan1 - 5ml Bottle86189Allergan781

Combigan eye drops contain two active ingredients, brimonidine tartrate and timolol maleate. These are both medicines that decrease raised pressure within the eye. They work in different ways to produce a combined effect greater than either medicine produces on its own.

As with any medicine, use of Combigan may cause side effects in some users. Do not be alarmed by
the list of side effects. You may not experience any of them.
In clinical trials of 12 months duration with COMBIGAN®, the most frequent reactions associated
with its use occurring in approximately 5% to 15% of the patients included:
• red enlarged blood vessels in the eye
• burning sensation
• stinging sensation
• itchy eye
• allergic reaction in the eye
• inflammation of the eyelid
The following adverse reactions were reported in 1% to 5% of patients:
• watery eyes
• redness of the inner surface of the eye and eyelid
• eye pain
• eye dryness
• visual disturbance
• foreign body sensation in the eye
• eye discharge
• swollen eyelid
• itchy eyelid
• eye irritation
• Small abrasions of the surface of the eye
• headache
• feeling weak
• depression
• high blood pressure
• dry mouth
• feeling drowsy.

Combigan is used to reduce high pressure in the eye in patients with open-angle glaucoma or ocular hypertension. The medicine contains two active ingredients: brimonidine, which belongs to a group of medicines called alpha-adrenergic receptor agonists, and timolol which belongs to a group of medicines called beta-blockers. Both of these active ingredients reduce pressure in the eye.


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