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  • US Name:


  • Generic Names:


  • Active Ingredients:

    Formoterol Fumarate; Glycopyrronium; Budesonide

  • Brand Manufacturer:

    Astra Zeneca

  • Manufacturer Location:

  • Click here to view Product Insert

  • Click here to view Product Insert


Prescription Required

Breztri / Trixeo Aerosphere is a maintenance treatment for adult patients with moderate to severe chronic obstructive pulmonary disease (COPD)

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Trixeo Aerosphere Brand 5mcg/7.2mcg/160mcg
120 Doses
Our price: $121.00

*Please note all prices are in US dollars
Breztri / Trixeo Aerosphere (budesonide + glycopyrronium + formoterol fumarate) is prescribed as a maintenance treatment for adult patients with moderate to severe chronic obstructive pulmonary disease (COPD) who are not adequately treated by a combination of long-acting beta2-agonists and either corticosteroids or long-acting muscarinic antagonists. Formoterol fumarate and glycopyrronium belong to the group of medicines known as bronchodilators. Budesonide is a corticosteroid. Breztri is intended for the long-term maintenance treatment for COPD. It should not be used for sudden attacks of breathing problems. It also does not treat people with asthma. People with COPD or asthma should have a quick-relief inhaler such as Ventolin on hand at all times.


Only use Trixeo Aerosphere according to the doctor’s instructions. The usual dose is two inhalations twice a day, in the morning and evening. Use Trixeo Aerosphere every day, even if there are no symptoms of COPD. To remove any medicine which is left in the mouth, rinse it out with water after using Trixeo Aerosphere and spit the water out. Do not swallow.

This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication. 

Read the information leaflet that comes with the medication.

Most people who use Trixeo Aerosphere do not experience any negative side effects. Doctors prescribe Trixeo Aerosphere because they assess that the benefits that such treatment yields outweighs any likely unwanted effects.

If after taking a puff of Trixeo Aerosphere a sudden allergic reaction (anaphylaxis) occurs, with symptoms like swelling of the face, tongue or throat making it difficult to breathe or swallow, or there is wheezing, hives, rash, blistering or peeling of the skin, call a doctor or 911 right away, or go to an emergency room immediately.

Some of the side effects that have been reported include:

  • A fungal infection in the mouth (thrush). Rinsing the mouth out immediately after using Trixeo Aerosphere may help prevent this
  • Feeling anxious
  • Difficulty sleeping
  • Nausea
  • Headache
  • Coughing or a hoarse voice
  • Muscle cramps
  • Palpitations (awareness of your heart beating)
  • Painful and frequent urination (which may be signs of a urinary tract infection)
  • Pneumonia.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.

The most common symptoms of chronic obstructive pulmonary disease (COPD) are shortness of breath, coughing that brings up mucus or phlegm, wheezing or chest tightness, constant fatigue or tiredness. People with COPD are subject to reoccurring lung infections such as acute bronchitis or pneumonia. A firm diagnosis of COPD can only be given after a test called a spirometry test has been performed. The test measures how much air a person can breathe in and out, as well as how easily and fast the subject can blow air out of their lungs.

  • What stage of COPD requires an inhaler?
    Treatment of chronic obstructive pulmonary disease (COPD) is graded according to the symptoms. In stage 1, doctors usually prescribe a bronchodilator like Trixeo Aerosphere. It can open up the airways in the lungs and relieve symptoms, but it is not a cure. There is no cure for COPD.
  • Does Breztri improve lung function?
    The combination of budesonide, glycopyrronium and formoterol fumarate in Breztri improves lung function and makes it easier to breathe. Breztri Aerosphere can reduce the number of COPD flare-ups and lower the risk of hospitalization. Breztri Aerosphere only treats COPD and is not used to treat asthma.
  • Does Trixeo Aerosphere have a steroid in it?
    Breztri inhaler combines an anticholinergic (glycopyrronium), a corticosteroid (ICS) (budesonide), and a long-acting beta2-adrenergic agonist (LABA) (formoterol fumarate) in one inhaler.
  • Can you just stop using Trixeo Aerosphere?
    Do not change the dose, either by using the inhaler more often, or by stopping using it, without first consulting a doctor. The condition will not improve any faster, and the risk of side effects will increase.

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