Azilect (rasagiline) is used on its own to treat early Parkinson’s Disease and can be combined with levodopa for the treatment of advanced Parkinson’s. Rasagiline is a monoamine oxidase-B (MAO-B) inhibitor. It works by increasing the levels of neurotransmitters like dopamine, norepinephrine, and serotonin in the brain.
Dosage
The dosage and regime is set by the prescribing physician. The usual recommended dose in monotherapy is 1 mg once daily, or 0.5 mg when combined with levodopa. The dose may be increased to 1 mg once daily if the response is inadequate.
This text is for informational purposes only. Please consult with a doctor or pharmacist before using any medication. Doctors prescribe rasagiline because they have judged that the benefits outweigh the risks of any side effects.
Mild side effects like drowsiness or dizziness, joint pain, abdominal pain, heartburn or nausea, or dry mouth may occur.
People can reduce the risk of dizziness and lightheadedness by getting up slowly from sitting or lying, especially when starting on Azilect.
Not all possible side effects can be listed here. If any of these or other unexpected side effects persist or worsen, consult a doctor or pharmacist.
Parkinson’s Disease typically starts with subtle symptoms that gradually worsen. The ones commonly observed are:
- Tremors which mainly start in one hand, known as “resting tremors.”
- Bradykinesia (slowness of movement), which shows up as a reduction in spontaneous movement.
- Persistent stiffness in the limbs and trunk (muscle rigidity).
- Balance problems and increased risk of falls (postural instability).
Parkinson’s Disease is not curable and is usually progressive over time. It cannot be directly diagnosed by blood tests or imaging. Doctors try to make a clinical diagnosis primarily based on medical history, an assessment of motor skills, balance, coordination, and reflexes. A specialized imaging test (DaTscan) that looks at the dopamine system in the brain can distinguish between Parkinson’s and other neurological disorders.