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  • US Name:

    Xgeva

  • Generic Names:

    Xgeva

  • Active Ingredients:

    Denosumab

  • Brand Manufacturer:

    Amgen

  • Manufacturer Location:

    Netherlands

  • Click here to view Product Insert

  • Click here to view Product Insert

  • Click here to view Product Insert

Xgeva

Prescription Required

Xgeva is used to prevent bone fractures in people with bone cancer caused by solid tumors or with multiple myeloma.

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Xgeva Brand 120mg
1 Vial
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Our price: $954.00

*Please note all prices are in US dollars
Xgeva (generic name: denosumab) is a human monoclonal antibody prescribed to prevent bone fractures in people with bone cancer caused by solid tumors or in people with multiple myeloma. It is also used to treat Giant Cell tumors, which are a type of bone tumor when they cannot be removed with surgery, and high blood calcium levels that are caused by cancer that has not improved after taking a bisphosphonate drug.

Caution

Women of childbearing age should use effective methods of contraception while being treated with Xgeva and for at least 5 months after stopping treatment. In case you become pregnant during treatment with Xgeva or within 5 months after stopping treatment, please inform your doctor immediately.

Dosage

Xgeva is administered only by professional healthcare providers. Please read the information on the manufacturer’s Product leaflet that comes with the medication and follow the doctor’s instructions. The usual recommended dosage is a single subcutaneous injection administered once every 6 months.

This text is for informational purposes only. Please consult your doctor or pharmacist before using any medication.

Possible side effects of Xgeva include:

  • low calcium levels (especially if you have kidney problems)
  • weakness
  • constipation
  • back pain
  • muscle pain
  • pain in the arms and legs
  • anemia
  • diarrhea
  • skin problems (eczema, blisters, dry skin, peeling, redness, itching, small bumps)

There may be a greater likelihood of a severe infection, such as skin, ear, stomach/gut, or bladder infection while taking Xgeva.

Inform a doctor immediately if there are signs of infection while taking the medication, such as:

  • fever/chills, night sweats
  • red/swollen/tender/warm skin
  • severe stomach or abdominal pain
  • ear pain or drainage, trouble hearing
  • frequent/painful/burning urination, or pink/bloody urine
  • severe itching, burning, rash, blistering, peeling, or dryness of the skin
  • cough or shortness of breath
  • pinpoint purple or red spots under your skin
  • flu symptoms
  • weight loss

 

Please take time to read the manufacturer’s Product Insert that comes with the medication. Not all side effects are listed here. Consult a healthcare provider if you experience these or other unexpected effects.

Xgeva is used to treat people who have been diagnosed with Giant Cell bone tumor, which is a fast-growing noncancerous tumor if it cannot be removed with surgery. It is also used to prevent bone fractures in people with bone cancer caused by solid tumors or multiple myeloma, and to lower calcium levels in the blood caused by various bone cancers.

  • What does Xgeva do to bones?
    Xgeva (denosumab) helps treat serious bone problems in people with multiple myeloma. Xgeva works to slow bone breakdown in people with bone cancer caused by solid tumors, and treats high calcium levels in the blood due to cancer, and bone tumors.
  • Does Xgeva have long-term side effects?
    Xgeva have long-term side effects. It can lead osteonecrosis (loss of bone cells) in the jaw and a high risk of serious infections, such as pneumonia
  • What happens if you stop taking denosumab abruptly?
    Discontinuing treatment with denosumab may be risky. A rebound in bone turnover with subsequent bone loss and a possibility of multiple vertebral fractures. can result from the rapid reversal following cessation.
  • Who should not be treated with denosumab?
    Doctors will not normally prescribe denomusab for patients with who are pregnant or planning to become pregnant; breastfeeding or planning to breastfeed; have a low blood calcium level; have kidney problems; have a planned dental procedure, including dental surgery.

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